| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
nickel
Nickel: A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.. nickel ion : A nickel atom having a net electric charge.. nickel atom : Chemical element (nickel group element atom) with atomic number 28. | 2.07 | 1 | 0 | metal allergen;
nickel group element atom | epitope;
micronutrient |
phosphorylcholine
Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.. phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family. | 2.01 | 1 | 0 | phosphocholines | allergen;
epitope;
hapten;
human metabolite;
mouse metabolite |
alanine
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.. alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2. | 2.72 | 3 | 0 | alanine zwitterion;
alanine;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid | EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
fundamental metabolite |
copper gluconate
Gluconates: Derivatives of gluconic acid (the structural formula HOCH2(CHOH)4COOH), including its salts and esters. | 2.07 | 1 | 0 | organic molecular entity | |
uridine diphosphate n-acetylglucosamine
Uridine Diphosphate N-Acetylglucosamine: Serves as the biological precursor of insect chitin, of muramic acid in bacterial cell walls, and of sialic acids in mammalian glycoproteins. | 1.99 | 1 | 0 | | |
vancomycin
Vancomycin: Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to RISTOCETIN that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear.. vancomycin : A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile. | 8.25 | 6 | 0 | glycopeptide | antibacterial drug;
antimicrobial agent;
bacterial metabolite |
palladium
Palladium: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.. palladium : Chemical element (nickel group element atom) with atomic number 46. | 2.07 | 1 | 0 | metal allergen;
nickel group element atom;
platinum group metal atom | |
glycidyl nitrate
glycidyl nitrate: a nitric oxide donor; structure in first source. peptidoglycan : A peptidoglycosaminoglycan formed by alternating residues of beta-(1->4)-linked N-acetylglucosamine and N-acetylmuramic acid {2-amino-3-O-[(S)-1-carboxyethyl]-2-deoxy-D-glucose} residues. Attached to the carboxy group of the muramic acid is a peptide chain of three to five amino acids. | 3.25 | 6 | 0 | | |
lanthionine
lanthionine: a thioether analogue of cystine; RN given refers to (DL)-isomer; structure; a component of lantibiotics (BACTERIOCINS). lanthionine : An alanine derivative in which two alanine residues are linked on their beta-carbons by a thioether linkage. | 2.72 | 3 | 0 | alanine derivative;
non-proteinogenic alpha-amino acid;
organic sulfide | bacterial metabolite |
2-oxo-3-deoxygalactonic acid
2-dehydro-3-deoxy-D-galactonic acid : The 2-dehydro-3-deoxy derivative of D-galactonic acid. | 2.07 | 1 | 0 | hexonic acid;
ketoaldonic acid | Escherichia coli metabolite |
flavin-adenine dinucleotide
Flavin-Adenine Dinucleotide: A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) | 2.01 | 1 | 0 | flavin adenine dinucleotide;
vitamin B2 | cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prosthetic group |
dodecylphosphocholine
dodecylphosphocholine: phospholipase A2 inhibitor; RN refers to chloride. dodecylphosphocholine : A phosphocholine that is the monododecyl ester of phosphocholine | 7.01 | 1 | 0 | phosphocholines | detergent |
2-keto-3-deoxy-6-phosphogluconate
2-keto-3-deoxy-6-phosphogluconate: structure given in first source; an intermediate in glucose metabolism. 2-dehydro-3-deoxy-6-phospho-D-gluconic acid : The 5-phospho derivative of 2-dehydro-D-gluconic acid. | 2.07 | 1 | 0 | ketoaldonic acid phosphate | Escherichia coli metabolite |
cysteine
Cysteine: A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.. L-cysteinium : The L-enantiomer of cysteinium.. cysteine : A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3. | 7.74 | 3 | 0 | cysteinium | fundamental metabolite |
udp-n-acetylmuramic acid pentapeptide
[no description available] | 1.99 | 1 | 0 | | |
gardimycin
gardimycin: a globular type B lantibiotic; from actinoplanes | 2.72 | 3 | 0 | | |
uridine diphosphate n-acetylmuramic acid
Uridine Diphosphate N-Acetylmuramic Acid: A nucleoside diphosphate sugar which is formed from UDP-N-acetylglucosamine and phosphoenolpyruvate. It serves as the building block upon which peptidoglycan is formed.. UDP-N-acetyl-alpha-D-muramate(3-) : A UDP-N-acetyl-D-muramate(3-) in which the anomeric centre of the pyranose fragment has alpha-configuration. | 4.38 | 6 | 0 | UDP-N-acetylmuramate(3-) | |
epidermin
epidermin: a linear type A lantibiotic; tetracyclic 21-peptide amide antibiotic produced by Staphylococcus epidermis. epidermin : A type A lantibiotic that is a tetracyclic 21-amino-acid peptide which contains meso-lanthionine, 3-methyllanthionine, and S-(2-aminovinyl)-D-cysteine. It is obtained from Staphylococcus epidermidis Tue 3298 and exhibits antibiotic activity against many Gram-positive bacteria. | 3.78 | 3 | 0 | macrocycle;
type A lantibiotic | antibacterial agent;
metabolite |
mannopeptimycin
mannopeptimycin: structure in first source | 3.13 | 1 | 0 | | |
undecaprenyl diphosphate-(n-acetylglucosaminyl)(1-4)-n-acetylmuramoyl pentapeptide
undecaprenyl diphosphate-(N-acetylglucosaminyl)(1-4)-N-acetylmuramoyl pentapeptide: murein precursor | 2.4 | 2 | 0 | | |
daptomycin
[no description available] | 7.41 | 2 | 0 | | |
lanthiopeptin
lanthiopeptin: Isolated from Streptoverticillium griseoverticillatum; contains 15 amino acids; structure given in first source. cinnamycin : A type B lantibiotic consisting of a 19 amino acid tetracyclic polypeptide produced by Streptomyces cinnamoneus. | 1.98 | 1 | 0 | heterodetic cyclic peptide;
L-cysteine thioether;
macrocycle;
type B lantibiotic | |
planosporicin
planosporicin: isolated from Planomonospora; structure in first source | 2.03 | 1 | 0 | | |
gallidermin
gallidermin: lanthionine-containing peptide antibiotic (lantibiotic); from Staphylococcus gallinarum; structure given in first source | 2.42 | 2 | 0 | | |