| Assay ID | Title | Year | Journal | Article |
|---|
| AID550209 | Antimitotic activity against Paracentrotus lividus embryo assessed as cleavage alteration after 2.5 to 6 hrs post fertilization by sea urchin embryo assay | 2010 | Journal of natural products, Nov-29, Volume: 73, Issue:11
| Synthesis of antimitotic polyalkoxyphenyl derivatives of combretastatin using plant allylpolyalkoxybenzenes. |
| AID391280 | Cytotoxicity against human H460 cells by sulforhodamine B test | 2008 | Journal of medicinal chemistry, Oct-09, Volume: 51, Issue:19
| Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity. |
| AID421860 | Antitumor activity against human NCI-H460 cells by sulforhodamine B assay | 2009 | Journal of natural products, Mar-27, Volume: 72, Issue:3
| Antineoplastic agents. 578. Synthesis of stilstatins 1 and 2 and their water-soluble prodrugs. |
| AID214341 | Percent inhibitory activity (2 uM) against colchicine binding to tubulin in mitosis in MCF-7 breast cancer cells | 2003 | Journal of medicinal chemistry, Feb-13, Volume: 46, Issue:4
| Antineoplastic agents. 487. Synthesis and biological evaluation of the antineoplastic agent 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene and derived amino acid amides. |
| AID550211 | Antimitotic activity against Paracentrotus lividus embryo assessed as embryo spinning after 0.5 to 20 hrs post dose by sea urchin embryo assay | 2010 | Journal of natural products, Nov-29, Volume: 73, Issue:11
| Synthesis of antimitotic polyalkoxyphenyl derivatives of combretastatin using plant allylpolyalkoxybenzenes. |
| AID45939 | Inhibitory activity against CNS SF-295 cell line | 2003 | Journal of medicinal chemistry, Feb-13, Volume: 46, Issue:4
| Antineoplastic agents. 487. Synthesis and biological evaluation of the antineoplastic agent 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene and derived amino acid amides. |
| AID99250 | Inhibitory activity against leukemia P388 cell line | 2003 | Journal of medicinal chemistry, Feb-13, Volume: 46, Issue:4
| Antineoplastic agents. 487. Synthesis and biological evaluation of the antineoplastic agent 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene and derived amino acid amides. |
| AID391278 | Cytotoxicity against BMEC by sulforhodamine B test | 2008 | Journal of medicinal chemistry, Oct-09, Volume: 51, Issue:19
| Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity. |
| AID421862 | Antitumor activity against human DU145 cells by sulforhodamine B assay | 2009 | Journal of natural products, Mar-27, Volume: 72, Issue:3
| Antineoplastic agents. 578. Synthesis of stilstatins 1 and 2 and their water-soluble prodrugs. |
| AID214345 | Percent inhibitory activity (5 uM) against colchicine binding to tubulin in mitosis in MCF-7 breast cancer cells | 2003 | Journal of medicinal chemistry, Feb-13, Volume: 46, Issue:4
| Antineoplastic agents. 487. Synthesis and biological evaluation of the antineoplastic agent 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene and derived amino acid amides. |
| AID421857 | Antitumor activity against human BxPC3 cells by sulforhodamine B assay | 2009 | Journal of natural products, Mar-27, Volume: 72, Issue:3
| Antineoplastic agents. 578. Synthesis of stilstatins 1 and 2 and their water-soluble prodrugs. |
| AID1068638 | Microtubule destabilizing activity in sea urchin free-swimming blastula assessed as embryo spinning treated at 9 to 10 hrs post-fertilization measured after 0.15 to 15 hrs | 2014 | European journal of medicinal chemistry, Feb-12, Volume: 73 | 3-(5-)-Amino-o-diarylisoxazoles: regioselective synthesis and antitubulin activity. |
| AID1064436 | Antimitotic activity against sea urchin embryo model assessed as cleavage alteration of fertilized egg compound treated at 8 to 20 mins post-fertilization and 45 to 55 mins prior to first mitotic cycle completion measured 2.5 to 5.5 hrs post-fertilization | 2014 | Bioorganic & medicinal chemistry, Jan-15, Volume: 22, Issue:2
| Synthesis and antiproliferative activity of conformationally restricted 1,2,3-triazole analogues of combretastatins in the sea urchin embryo model and against human cancer cell lines. |
| AID103372 | Percent inhibitory activity (5 uM) against colchicine binding to tubulin in mitosis in MCF-7 breast cancer cells | 2003 | Journal of medicinal chemistry, Feb-13, Volume: 46, Issue:4
| Antineoplastic agents. 487. Synthesis and biological evaluation of the antineoplastic agent 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene and derived amino acid amides. |
| AID157512 | Inhibitory activity against pancreatic BXPC-3 cell line | 2003 | Journal of medicinal chemistry, Feb-13, Volume: 46, Issue:4
| Antineoplastic agents. 487. Synthesis and biological evaluation of the antineoplastic agent 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene and derived amino acid amides. |
| AID550210 | Antimitotic activity against Paracentrotus lividus embryo assessed as cleavage arrest after 2.5 to 6 hrs post fertilization by sea urchin embryo assay | 2010 | Journal of natural products, Nov-29, Volume: 73, Issue:11
| Synthesis of antimitotic polyalkoxyphenyl derivatives of combretastatin using plant allylpolyalkoxybenzenes. |
| AID421856 | In vivo antitumor activity against mouse P388 cells | 2009 | Journal of natural products, Mar-27, Volume: 72, Issue:3
| Antineoplastic agents. 578. Synthesis of stilstatins 1 and 2 and their water-soluble prodrugs. |
| AID43452 | Inhibitory activity against breast MCF-7 cell line | 2003 | Journal of medicinal chemistry, Feb-13, Volume: 46, Issue:4
| Antineoplastic agents. 487. Synthesis and biological evaluation of the antineoplastic agent 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene and derived amino acid amides. |
| AID481679 | Antimitotic activity against Paracentrotus lividus embryo assessed as cleavage arrest after 10 to 15 mins fertilization 45 to 60 mins before first mitotic cycle completeion | 2010 | European journal of medicinal chemistry, May, Volume: 45, Issue:5
| Novel derivatives of 1,3,4-oxadiazoles are potent mitostatic agents featuring strong microtubule depolymerizing activity in the sea urchin embryo and cell culture assays. |
| AID1068640 | Antimitotic activity in sea urchin fertilized egg assessed as cleavage alteration treated at 8 to 20 mins post-fertilization measured at 2.5 to 5.5 hrs post-fertilization | 2014 | European journal of medicinal chemistry, Feb-12, Volume: 73 | 3-(5-)-Amino-o-diarylisoxazoles: regioselective synthesis and antitubulin activity. |
| AID102527 | Inhibitory activity against lung NSC NCI-H460 cell line | 2003 | Journal of medicinal chemistry, Feb-13, Volume: 46, Issue:4
| Antineoplastic agents. 487. Synthesis and biological evaluation of the antineoplastic agent 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene and derived amino acid amides. |
| AID1068639 | Antimitotic activity in sea urchin fertilized egg assessed as cleavage arrest treated at 8 to 20 mins post-fertilization measured at 2.5 to 5.5 hrs post-fertilization | 2014 | European journal of medicinal chemistry, Feb-12, Volume: 73 | 3-(5-)-Amino-o-diarylisoxazoles: regioselective synthesis and antitubulin activity. |
| AID421861 | Antitumor activity against human KM20L2 cells by sulforhodamine B assay | 2009 | Journal of natural products, Mar-27, Volume: 72, Issue:3
| Antineoplastic agents. 578. Synthesis of stilstatins 1 and 2 and their water-soluble prodrugs. |
| AID421858 | Antitumor activity against human MCF7 cells by sulforhodamine B assay | 2009 | Journal of natural products, Mar-27, Volume: 72, Issue:3
| Antineoplastic agents. 578. Synthesis of stilstatins 1 and 2 and their water-soluble prodrugs. |
| AID481678 | Antiproliferative activity against Paracentrotus lividus embryo assessed as cleavage alteration after 10 to 15 mins fertilization 45 to 60 mins before first mitotic cycle completeion | 2010 | European journal of medicinal chemistry, May, Volume: 45, Issue:5
| Novel derivatives of 1,3,4-oxadiazoles are potent mitostatic agents featuring strong microtubule depolymerizing activity in the sea urchin embryo and cell culture assays. |
| AID391279 | Cytotoxicity against human HT29 cells by sulforhodamine B test | 2008 | Journal of medicinal chemistry, Oct-09, Volume: 51, Issue:19
| Novel A-ring and B-ring modified combretastatin A-4 (CA-4) analogues endowed with interesting cytotoxic activity. |
| AID481680 | Cytotoxicity against Paracentrotus lividus embryo assessed as embryo spinning after 9 to 12 hrs fertilization and 0.5 to 20 hrs treatment | 2010 | European journal of medicinal chemistry, May, Volume: 45, Issue:5
| Novel derivatives of 1,3,4-oxadiazoles are potent mitostatic agents featuring strong microtubule depolymerizing activity in the sea urchin embryo and cell culture assays. |
| AID103369 | Inhibitory activity against tubulin (1.0 mg/mL) assembly was determined | 2003 | Journal of medicinal chemistry, Feb-13, Volume: 46, Issue:4
| Antineoplastic agents. 487. Synthesis and biological evaluation of the antineoplastic agent 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene and derived amino acid amides. |
| AID580346 | Antiproliferative activity against sea urchin embryo assessed as cleavage alteration after 10 to 15 mins fertilization 45 to 60 mins before first mitotic cycle completion | 2011 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 21, Issue:6
| Application of plant allylpolyalkoxybenzenes in synthesis of antimitotic phenstatin analogues. |
| AID161225 | Inhibitory activity against prostate DU145 cell line | 2003 | Journal of medicinal chemistry, Feb-13, Volume: 46, Issue:4
| Antineoplastic agents. 487. Synthesis and biological evaluation of the antineoplastic agent 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene and derived amino acid amides. |
| AID90279 | In vitro antitumor activity against human tumor cancer cell lines | 1995 | Journal of medicinal chemistry, May-12, Volume: 38, Issue:10
| Antineoplastic agents. 291. Isolation and synthesis of combretastatins A-4, A-5, and A-6(1a) |
| AID1064434 | Antimitotic activity against sea urchin embryo free-swimming blastula model assessed as embryo spinning compound treated at 8 to 10 hrs post-fertilization measured after 0.25 to 20 hrs | 2014 | Bioorganic & medicinal chemistry, Jan-15, Volume: 22, Issue:2
| Synthesis and antiproliferative activity of conformationally restricted 1,2,3-triazole analogues of combretastatins in the sea urchin embryo model and against human cancer cell lines. |
| AID397287 | Cytotoxicity against human NCI60 cells | 2009 | Journal of medicinal chemistry, Jul-23, Volume: 52, Issue:14
| Isocombretastatins a versus combretastatins a: the forgotten isoCA-4 isomer as a highly promising cytotoxic and antitubulin agent. |
| AID580347 | Antiproliferative activity against sea urchin embryo assessed as cleavage arrest after 10 to 15 mins fertilization 45 to 60 mins before first mitotic cycle completion | 2011 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 21, Issue:6
| Application of plant allylpolyalkoxybenzenes in synthesis of antimitotic phenstatin analogues. |
| AID1064435 | Antimitotic activity against sea urchin embryo model assessed as cleavage arrest of fertilized egg compound treated at 8 to 20 mins post-fertilization and 45 to 55 mins prior to first mitotic cycle completion measured 2.5 to 5.5 hrs post-fertilization | 2014 | Bioorganic & medicinal chemistry, Jan-15, Volume: 22, Issue:2
| Synthesis and antiproliferative activity of conformationally restricted 1,2,3-triazole analogues of combretastatins in the sea urchin embryo model and against human cancer cell lines. |
| AID580348 | tubulin-destabilizing activity in sea urchin embryo assessed as embryo spinning treated immediately 8 to 10 hrs after fertilization | 2011 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 21, Issue:6
| Application of plant allylpolyalkoxybenzenes in synthesis of antimitotic phenstatin analogues. |
| AID50589 | Inhibitory activity against colon KM2OL2 cell line | 2003 | Journal of medicinal chemistry, Feb-13, Volume: 46, Issue:4
| Antineoplastic agents. 487. Synthesis and biological evaluation of the antineoplastic agent 3,4-methylenedioxy-5,4'-dimethoxy-3'-amino-Z-stilbene and derived amino acid amides. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |