2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 43264 |
| CHEMBL ID | 79720 |
| SCHEMBL ID | 1370802 |
| MeSH ID | M0096111 |
| Synonym |
|---|
| CHEMBL79720 , |
| 2,4,6-cycloheptatrien-1-one, 2-methoxy-5-(2,3,4-trimethoxyphenyl)- |
| 2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone |
| brn 4324860 |
| nsc-367601 |
| nsc367601 |
| 60423-21-4 |
| 2-methoxy-5-(2,3,4-trimethoxyphenyl)cyclohepta-2,4,6-trien-1-one |
| 2-methoxy-5-(2,3,4-trimethoxyphenyl)- |
| 2-methoxy-5-(2,3,4-trimethoxy-phenyl)-cyclohepta-2,4,6-trienone |
| bdbm50279934 |
| 2-methoxy-5-(2,3,4-trimethoxyphenyl)-2,4,6-cycloheptatrien-1-one |
| nsc 367601 |
| unii-xlq3sgl8dp |
| xlq3sgl8dp , |
| SCHEMBL1370802 |
| DTXSID40209176 |
| 8wb , |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID288670 | Displacement of MTC from tubulin | 2007 | Journal of medicinal chemistry, Jun-14, Volume: 50, Issue:12 | Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studies. |
| AID1178971 | Immunosuppressive activity in B cells (unknown origin) assessed as inhibition of LPS-induced cell proliferation at 3 to 30 ng/mL | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Discovery of structurally simplified analogs of colchicine as an immunosuppressant. |
| AID1178972 | Immunosuppressive activity in T cells (unknown origin) assessed as inhibition of Con A-induced cell proliferation at 3 to 30 ng/mL | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Discovery of structurally simplified analogs of colchicine as an immunosuppressant. |
| AID1714650 | Binding affinity to calf brain tubulin assessed as compound-protein complex stoichiometry ratio of 1:1 in absence of Mg2+ by spectrofluorometry analysis | 2018 | Journal of natural products, 03-23, Volume: 81, Issue:3 | Zampanolide Binding to Tubulin Indicates Cross-Talk of Taxane Site with Colchicine and Nucleotide Sites. |
| AID1714649 | Binding affinity to zampanolide-modified calf brain tubulin | 2018 | Journal of natural products, 03-23, Volume: 81, Issue:3 | Zampanolide Binding to Tubulin Indicates Cross-Talk of Taxane Site with Colchicine and Nucleotide Sites. |
| AID1714651 | Binding affinity to zampanolide-modified calf brain tubulin assessed as compound-protein complex stoichiometry ratio of 1:1 in absence of Mg2+ by spectrofluorometry assay | 2018 | Journal of natural products, 03-23, Volume: 81, Issue:3 | Zampanolide Binding to Tubulin Indicates Cross-Talk of Taxane Site with Colchicine and Nucleotide Sites. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 11 (36.67) | 18.7374 |
| 1990's | 10 (33.33) | 18.2507 |
| 2000's | 5 (16.67) | 29.6817 |
| 2010's | 3 (10.00) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (3.23%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 30 (96.77%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||