Page last updated: 2024-11-04

chlamydocin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

chlamydocin: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID2706
MeSH IDM0049826

Synonyms (3)

Synonym
chlamydocin
(3s,9s,12r)-3-benzyl-6,6-dimethyl-9-[6-[(2s)-oxiran-2-yl]-6-oxohexyl]-1,4,7,10-tetrazabicyclo[10.3.0]pentadecane-2,5,8,11-tetrone
BS-1305

Research Excerpts

Overview

Chlamydocin is a cyclic tetrapeptide containing an epoxyketone moiety in the side chain. This makes it an irreversible inhibitor of HDACs.

ExcerptReferenceRelevance
"Chlamydocin is a cyclic tetrapeptide containing an epoxyketone moiety in the side chain that makes it an irreversible inhibitor of HDAC."( Chlamydocin-hydroxamic acid analogues as histone deacetylase inhibitors.
Jose, B; Kato, T; Komatsu, Y; Nishino, N; Shinta, R; Yoshida, M, 2004
)
2.49
"Chlamydocin is a cyclic tetrapeptide containing an epoxyketone surrogate in the side chain which makes it irreversible inhibitor of HDACs, whereas apicidins are a class of cyclic tetrapeptides that contain an ethylketone moiety as zinc ligand."( Chlamydocin analogs bearing carbonyl group as possible ligand toward zinc atom in histone deacetylases.
Bhuiyan, MP; Kato, T; Maeda, S; Nishino, N; Nishino, TG; Okauchi, T; Yoshida, M, 2006
)
2.5
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (18)

TimeframeStudies, This Drug (%)All Drugs %
pre-19905 (27.78)18.7374
1990's2 (11.11)18.2507
2000's7 (38.89)29.6817
2010's3 (16.67)24.3611
2020's1 (5.56)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 31.44

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index31.44 (24.57)
Research Supply Index3.00 (2.92)
Research Growth Index4.76 (4.65)
Search Engine Demand Index39.34 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (31.44)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other19 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]