ascidiacyclamide: structure given in first source; isolated from the marine tunicate Ascidian [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 163527 |
| CHEMBL ID | 1778796 |
| CHEBI ID | 80067 |
| SCHEMBL ID | 2930454 |
| MeSH ID | M0204130 |
| Synonym |
|---|
| ascidiacyclamide |
| 86701-12-4 |
| CHEMBL1778796 |
| chebi:80067 , |
| ulithiacyclamide, 1,15-de(dithiobis(methylene))-8,22-bis(1-methylethyl)-1,15-bis(1-methylpropyl)- |
| cyclo(thiazole-d-valyl-oxazoline-l-isoleucyl)2 |
| cyclo(thiazole-d-val-oxazoline-l-ile)2 |
| SCHEMBL2930454 |
| Q27149219 |
| (4s,7r,8s,11r,18s,21r,22s,25r)-4,18-bis[(2s)-butan-2-yl]-7,21-dimethyl-11,25-di(propan-2-yl)-6,20-dioxa-13,27-dithia-3,10,17,24,29,30,31,32-octazapentacyclo[24.2.1.15,8.112,15.119,22]dotriaconta-1(28),5(32),12(31),14,19(30),26(29)-hexaene-2,9,16,23-tetron |
| 6,20-dioxa-13,27-dithia-3,10,17,24,29,30,31,32-octaazapentacyclo[24.2.1.15,8.112,15.119,22]dotriaconta-5(32),12(31),14,19(30),26(29),28-hexaene-2,9,16,23-tetrone, 7,21-dimethyl-11,25-bis(1-methylethyl)-4,18-bis[(1s)-1-methylpropyl]-, (4s,7r,8s,11r,18s,21r |
| Class | Description |
|---|---|
| cyclic peptide | |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID599007 | Cytotoxicity against mouse P388 cells after 72 hrs by MTT assay | 2011 | Bioorganic & medicinal chemistry, Jun-01, Volume: 19, Issue:11 | The square conformation of phenylglycine-incorporated ascidiacyclamide is stabilized by CH/π interactions between amino acid side chains. |
| AID1367068 | Cytotoxicity against mouse P388 cells after 72 hrs by MTT assay | 2017 | Bioorganic & medicinal chemistry, 12-15, Volume: 25, Issue:24 | Conformational properties of ascydiacyclamide analogues with cyclic α-amino acids instead of oxazoline residues. |
| AID599008 | Cytotoxicity against human HL60 cells after 72 hrs by MTT assay | 2011 | Bioorganic & medicinal chemistry, Jun-01, Volume: 19, Issue:11 | The square conformation of phenylglycine-incorporated ascidiacyclamide is stabilized by CH/π interactions between amino acid side chains. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 8 (47.06) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (11.96) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (5.88%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 16 (94.12%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||