| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
pteridines
[no description available] | 3.49 | 8 | 0 | azaarene;
mancude organic heterobicyclic parent;
ortho-fused heteroarene;
pteridines | |
sulfanilamide
[no description available] | 1.99 | 1 | 0 | substituted aniline;
sulfonamide antibiotic;
sulfonamide | antibacterial agent;
drug allergen;
EC 4.2.1.1 (carbonic anhydrase) inhibitor |
alanine
Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.. alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2. | 2.01 | 1 | 0 | alanine zwitterion;
alanine;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid | EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
fundamental metabolite |
arginine
Arginine: An essential amino acid that is physiologically active in the L-form.. arginine : An alpha-amino acid that is glycine in which the alpha-is substituted by a 3-guanidinopropyl group. | 7.42 | 2 | 0 | arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid | biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical |
2,4,6-triaminopyrimidine
2,4,6-triaminopyrimidine: see also 2,4,6-triaminopyridinium (cation). 2,4,6-triaminopyrimidine : An aminopyrimidine in which a pyrimidine core carries amino substituents at positions 2, 4 and 6. | 1.96 | 1 | 0 | aminopyrimidine | |
deuterium
Deuterium: The stable isotope of hydrogen. It has one neutron and one proton in the nucleus. | 1.96 | 1 | 0 | dihydrogen | |
nad
NAD(1-) : An anionic form of nicotinamide adenine dinucleotide arising from deprotonation of the two OH groups of the diphosphate moiety. | 1.96 | 1 | 0 | organophosphate oxoanion | cofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite |
6-hydroxymethyl-7,8-dihydropterin
2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-one : A dihydropterin that is 7,8-dihydropteridin-4-one substituted at positions 2 and 6 by amino and hydroxymethyl groups respectively.. 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol : A dihydropterin that is 7,8-dihydropteridin-4-ol substituted at positions 2 and 6 by amino and hydroxymethyl groups respectively. | 1.95 | 1 | 0 | dihydropterin | Saccharomyces cerevisiae metabolite |
sepiapterin
sepiapterin: A substrate of sepiapterin reductase | 7.44 | 2 | 0 | sepiapterin | |
7,8-dihydroneopterin
7,8-dihydroneopterin: an antioxidant. 7,8-dihydroneopterin : A neopterin where positions C-7 and C-8 have been hydrogenated. | 2.06 | 1 | 0 | dihydropterin;
neopterins | Escherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite |
dihydrofolate
dihydrofolic acid : A folic acid derivative acted upon by dihydrofolate reductase to produce tetrahydrofolic acid. It interacts with bacteria during cell division and is targeted by various drugs to prevent nucleic acid synthesis. | 1.97 | 1 | 0 | dihydrofolic acids | Escherichia coli metabolite;
mouse metabolite |
folic acid
folcysteine: used to promote fertility in chickens. vitamin B9 : Any B-vitamin that exhibits biological activity against vitamin B9 deficiency. Vitamin B9 refers to the many forms of folic acid and its derivatives, including tetrahydrofolic acid (the active form), methyltetrahydrofolate (the primary form found in blood), methenyltetrahydrofolate, folinic acid amongst others. They are present in abundance in green leafy vegetables, citrus fruits, and animal products. Lack of vitamin B9 leads to anemia, a condition in which the body cannot produce sufficient number of red blood cells. Symptoms of vitamin B9 deficiency include fatigue, muscle weakness, and pale skin. | 1.97 | 1 | 0 | folic acids;
N-acyl-amino acid | human metabolite;
mouse metabolite;
nutrient |
7,8-dihydrobiopterin
7,8-dihydrobiopterin: RN given refers to (S-(R*,S*))-isomer. 7,8-dihydrobiopterin : A dihydropterin that is biopterin dihydrogenated at positions 7 and 8.. L-erythro-7,8-dihydrobiopterin : A 7,8-dihydrobiopterin in which the 1,2-dihydroxypropyl group has (1R,2S)-configuration; naturally occurring form. | 2.4 | 2 | 0 | 7,8-dihydrobiopterin | |
dyspropterin
dyspropterin: intermediate in biosynthetic pathway of tetrahydrobiopterin; structure given in first source. dyspropterin : A tetrahydropterin that is 2-amino-5,6,7,8-tetrahydropteridin-4(3H)-one substituted by a 2-oxopropanoyl group at position 6. | 2.01 | 1 | 0 | biopterins;
tetrahydropterin | human metabolite;
metabolite;
mouse metabolite |
neopterin
[no description available] | 2.06 | 1 | 0 | | |
2-amino-4-hydroxy-6,7-dimethyl-5,6,7,8-tetrahydropteridine
2-amino-4-hydroxy-6,7-dimethyl-5,6,7,8-tetrahydropteridine: used as a synthetic cofactor in place of tetrahydrofolate; RN given refers to parent cpd; structure | 2.01 | 1 | 0 | pterins | |
6-hydroxymethylpterin
[no description available] | 2.02 | 1 | 0 | | |
tetrahydropterin
[no description available] | 1.97 | 1 | 0 | | |
drosopterin
drosopterin: eye pigments of Drosophila melanogaster; RN given refers to (trans)-(+-)-isomer; structure | 1.95 | 1 | 0 | | |
pyrimidinones
Pyrimidinones: Heterocyclic compounds known as 2-pyrimidones (or 2-hydroxypyrimidines) and 4-pyrimidones (or 4-hydroxypyrimidines) with the general formula C4H4N2O. | 1.96 | 1 | 0 | | |