Classes > dihydrofolic acids
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dihydrofolic acids

A group of heterocyclic compounds based on the 7,8-dihydropteroic acid skeleton conjugated with one or more L-glutamic acid units.

ChEBI ID: 23743

Members (2)

MemberDefinitionRole
10-formyldihydrofolateThe 10-formyl derivative of dihydrofolic acid.10-formyldihydrofolic acid
dihydrofolateA folic acid derivative acted upon by dihydrofolate reductase to produce tetrahydrofolic acid. It interacts with bacteria during cell division and is targeted by various drugs to prevent nucleic acid synthesis.dihydrofolic acid

Research

Studies (179)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199056 (31.28)18.7374
1990's52 (29.05)18.2507
2000's50 (27.93)29.6817
2010's19 (10.61)24.3611
2020's2 (1.12)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews9 (4.89%)6.00%
Case Studies2 (1.09%)4.05%
Observational0 (0.00%)0.25%
Other173 (94.02%)84.16%