Compounds > 2-hydroxylaminopropane
Page last updated: 2024-12-07

2-hydroxylaminopropane

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2-hydroxylaminopropane: RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID78763
CHEMBL ID140282
MeSH IDM0105000

Synonyms (31)

Synonym
3nt440v34t ,
2-propanamine, n-hydroxy-
unii-3nt440v34t
5080-22-8
einecs 225-791-1
n-hydroxyisopropylamine
ec 225-791-1
n-isopropylhydroxylamine
2-hydroxylaminopropane
CHEMBL140282
n-isopropyl-hydroxylamine
n-hydroxypropan-2-amine
n-propan-2-ylhydroxylamine
AKOS006230300
n-(propan-2-yl)hydroxylamine
isopropylhydroxylamine
n-isopropylhydroxylamine #
DTXSID6063694 ,
hydroxylamine, n-isopropyl-
n-hydroxy-2-propanamine
isopropyl hydroxyamine
mfcd02874394
FT-0719142
n-isopropylhydroxylamine;n-hydroxypropan-2-amine;2-propanamine, n-hydroxy-;2-hydroxylaminopropane;n-isopropylhydroxylamine n-hydroxypropan-2-amine 2-propanamine, n-hydroxy- 2-hydroxylaminopropane
EN300-112062
n-isopropylhydroxylamine (15% solution in water)
AT14836
Q27257766
SY277405
n-isopropylhydroxylamine, 15wt.% in h2o
Z1198161074
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID191494Toxicity (Ames Salmonella Test) in the presence of rat liver S-9 fraction in TA-100 strain (4*10e6 dilution)1983Journal of medicinal chemistry, Mar, Volume: 26, Issue:3
Derivatives of beta-adrenergic antagonists. N-Nitrosopropranolol and N-hydroxypropranolol and its aldonitrone.
AID184705Mutagenic activity (Ames Salmonella Test) in the presence of rat liver S-9 fraction in TA-98 strain1983Journal of medicinal chemistry, Mar, Volume: 26, Issue:3
Derivatives of beta-adrenergic antagonists. N-Nitrosopropranolol and N-hydroxypropranolol and its aldonitrone.
AID184702Mutagenic activity (Ames Salmonella Test) in the presence of rat liver S-9 fraction in TA-100 strain1983Journal of medicinal chemistry, Mar, Volume: 26, Issue:3
Derivatives of beta-adrenergic antagonists. N-Nitrosopropranolol and N-hydroxypropranolol and its aldonitrone.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.66

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.66 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.66)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
2-nitropropane
2-nitropropane: RN given refers to cpd with locant for nitro moiety in 2 position. 2-nitropropane : A secondary nitroalkane that is propane in which a hydrogen at position 2 has been replaced by a nitro group. Mainly used as a solvent (b.p. 120degreeC).		2.4120secondary nitroalkanecarcinogenic agent;
hepatotoxic agent;
polar aprotic solvent;
xenobiotic
3-methylcholanthrene
Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.. 3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.		1.9610ortho- and peri-fused polycyclic arenearyl hydrocarbon receptor agonist;
carcinogenic agent
deferoxamine
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.. desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.		210acyclic desferrioxaminebacterial metabolite;
ferroptosis inhibitor;
iron chelator;
siderophore
phenobarbital
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.. phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.		1.9610barbituratesanticonvulsant;
drug allergen;
excitatory amino acid antagonist;
sedative
edetic acid
Edetic Acid: A chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive.		210ethylenediamine derivative;
polyamino carboxylic acid;
tetracarboxylic acid		anticoagulant;
antidote;
chelator;
copper chelator;
geroprotector
propane
Propane: A three carbon alkane with the formula H3CCH2CH3.		2.4120alkane;
gas molecular entity		food propellant
propranolol hydrochloride
Inderex: combination of above cpds; used in treatment of hypertension		1.9610hydrochloride
hydroxylamine-o-sulfonic acid
hydroxylamine-O-sulfonic acid: structure		210
n-nitrosopropranolol
N-nitrosopropranolol: structure for (E)-isomer & RN given in first source		1.9610
heme
Heme: The color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins.. ferroheme : Any iron(II)--porphyrin coordination complex.. ferroheme b : Heme b in which the iron has oxidation state +2.. heme : A heme is any tetrapyrrolic chelate of iron.		210
deoxyguanosine
[no description available]		210purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
8-hydroxy-2'-deoxyguanosine
8-Hydroxy-2'-Deoxyguanosine: Common oxidized form of deoxyguanosine in which C-8 position of guanine base has a carbonyl group.. 8-hydroxy-2'-deoxyguanosine : Guanosine substituted at the purine 8-position by a hydroxy group. It is used as a biomarker of oxidative DNA damage.		210guanosinesbiomarker
ConditionIndicatedRelationship StrengthStudiesTrials