Page last updated: 2024-11-11
ym 758
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Description
YM 758: an If channel inhibitor; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Research Excerpts
Compound-Compound Interactions
Excerpt | Reference | Relevance |
---|---|---|
" The drug-drug interaction (DDI) potential of these drugs for the hOCT/rOct-mediated hepatic/renal uptake process was also assessed." | ( Effect of cationic drugs on the transporting activity of human and rat OCT/Oct 1-3 in vitro and implications for drug-drug interactions. Iwatsubo, T; Kamimura, H; Noguchi, K; Umehara, KI; Usui, T, 2008) | 0.35 |
Bioavailability
Excerpt | Reference | Relevance |
---|---|---|
" YM758 was well absorbed from all segments of the gastrointestinal tract except for the stomach." | ( Comparative evaluation of absorption, distribution, and excretion of YM758, a novel If channel inhibitor, between albino and non-albino rats. Kamimura, H; Nakamura, E; Noguchi, K; Seya, K; Sonoda, T; Umehara, KI; Usui, T, 2008) | 0.35 |
Dosage Studied
Excerpt | Relevance | Reference |
---|---|---|
" The recovery rates of radioactivity in urine and bile after oral dosing to bile duct-cannulated albino rats were 17." | ( Comparative evaluation of absorption, distribution, and excretion of YM758, a novel If channel inhibitor, between albino and non-albino rats. Kamimura, H; Nakamura, E; Noguchi, K; Seya, K; Sonoda, T; Umehara, KI; Usui, T, 2008) | 0.35 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Research
Studies (8)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 7 (87.50) | 29.6817 |
2010's | 1 (12.50) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 1 (11.11%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 8 (88.89%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |