Page last updated: 2024-12-07

viridicatol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Viridicatol is a natural product isolated from the fungus *Penicillium viridicatum*. It exhibits a wide range of biological activities, including antimicrobial, anti-inflammatory, and anticancer properties. Its unique chemical structure, characterized by a cyclopentenone ring and a spiro-fused lactone, has attracted significant interest in synthetic chemistry. Studies have focused on developing efficient synthetic routes to access viridicatol and its analogs, aiming to explore structure-activity relationships and identify potential therapeutic applications. Viridicatol's antiproliferative activity against various cancer cell lines has been particularly investigated, with potential applications in the treatment of leukemia and solid tumors. The compound's ability to inhibit the growth of bacteria and fungi has also been documented, making it a promising lead for developing new antimicrobial agents. Research on viridicatol is ongoing to understand its complex biological mechanisms and exploit its potential for drug development.'

Cross-References

ID SourceID
PubMed CID115033
MeSH IDM0282529

Synonyms (23)

Synonym
ACON0_001482
MEGXM0_000057
viridicatol
14484-44-7
3-hydroxy-4-(3-hydroxyphenyl)-1h-quinolin-2-one
2(1h)-quinolinone, 3-hydroxy-4-(3-hydroxyphenyl)-
45p12jne0l ,
3-hydroxy-4-(3-hydroxyphenyl)-2(1h)-quinolinone
unii-45p12jne0l
carbostyril, 3-hydroxy-4-(m-hydroxyphenyl)-
4-(3-hydroxyphenyl)-2,3-quinolinediol #
QIJIOTTYIGBOQA-UHFFFAOYSA-N
HY-116474
CS-0065593
3-hydroxy-4-(3-hydroxyphenyl)quinolin-2(1h)-one
nsc-794085
nsc794085
Q27258853
DTXSID60893995
3-hydroxy-4-(3-hydroxyphenyl) quinolin-2(1h)-one
F76730
3-hydroxy-4-(3-hydroxyphenyl)-1,2-dihydroquinolin-2-one
AKOS040740533

Research Excerpts

Overview

Viridicatol is a quinoline alkaloid isolated from the deep-sea-derived fungus.

ExcerptReferenceRelevance
"Viridicatol is a quinoline alkaloid isolated from the deep-sea-derived fungus "( Viridicatol Isolated from Deep-Sea
Cao, M; Liu, G; Liu, H; Liu, Q; Shu, Z; Xing, C; Yang, X; Zhang, J; Zhang, Y; Zhou, Y, 2020
)
3.44
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's2 (33.33)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]