Page last updated: 2024-11-11

vintoperol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

vintoperol: structure given in first source; no information given that it is a vinca alkaloid; RN refers to (3alpha, 16alpha)-isomer; RN for compound without isomeric designation not available 12/90 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
VincagenusA plant genus of the family Apocynaceae.[MeSH]ApocynaceaeThe dogbane family of the order Gentianales. Members of the family have milky, often poisonous juice, smooth-margined leaves, and flowers in clusters.[MeSH]

Cross-References

ID SourceID
PubMed CID6917973
CHEMBL ID2105559
SCHEMBL ID332109
MeSH IDM0182125

Synonyms (24)

Synonym
rt-3003
rgh-2981
vintoperol
(3-alpha,16-alpha)-14,15-dihydro-21-nor-1,14-secoeburnamenin-20-ol
(-)-(1s,12bs)-1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo(2,3-a)quinolizine-1-methanol
rgh 2981
vintoperol [inn]
21-nor-1,14-secoeburnamenin-20-ol, 14,15-dihydro-, (3-alpha,16-alpha)-
vintoperolum [inn-latin]
rt 3003
(-)-(1s,12bs)-1-ethyl-1-hydroxymethyl-1,2,3,4,6,7,12,12b-octahydroindolo(1,3-a)quinolizine
brn 4786095
[(1s,12bs)-1-ethyl-3,4,6,7,12,12b-hexahydro-2h-indolo[2,3-a]quinolizin-1-yl]methanol
is7c3gtw01 ,
unii-is7c3gtw01
vintoperolum
106498-99-1
CHEMBL2105559
SCHEMBL332109
rt3003 ,
((1s,12bs)-1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-1-yl)methanol
Q27280878
DTXSID001030624
AKOS040749752

Research Excerpts

Toxicity

ExcerptReferenceRelevance
"Myoblastic toxicity is a major adverse effect caused by reactive oxygen species (ROS) when exercising heavily."( Antioxidative effects of whey protein on peroxide-induced cytotoxicity.
Kong, B; Liu, N; Xu, R; Xu, X, 2011
)
0.37
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.13

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.13 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.13)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]