Page last updated: 2024-12-07

uk 21

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

UK 21: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID131785
SCHEMBL ID9768757
MeSH IDM0209524

Synonyms (11)

Synonym
134423-92-0
2',3',5'-tris-o-(n -(2-n-propyl-n-pentanoyl)glycyl)-5-fluorouridine
glycine, n-(1-oxo-2-propylpentyl)-, triester with 5-fluorouridine
uk 21
uk-21
[(2r,3r,4r,5r)-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3,4-bis[[2-(2-propylpentanoylamino)acetyl]oxy]oxolan-2-yl]methyl 2-(2-propylpentanoylamino)acetate
SCHEMBL9768757
DTXSID20158693
2',3',5'-tris-o-[n-(2-n-propyl-n-pentanoyl)glycyl]-5-fluorouridine
uk21
2',3',5'-tris-o-(n-(2-n-propyl-n-pentanoyl)glycyl)-5-fluorouridine

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
" However, the bioavailability of UK-21 given orally did not seem to be good."( Novel lowly immunosuppressive antitumor fluorouridine derivative, UK-21: antitumor activity and effect on humoral immune response in mice.
Kaku, Y; Kita, J; Koda, A; Maeda, D; Mori, H; Nagai, H; Nakayama, K, 1994
)
0.29
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's5 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 56.70

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index56.70 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index85.49 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (56.70)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]