Page last updated: 2024-09-03

uk 21 and glycine

uk 21 has been researched along with glycine in 5 studies

*Glycine: A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter. [MeSH]

*Glycine: A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter. [MeSH]

Compound Research Comparison

Studies
(uk 21)
Trials
(uk 21)
Recent Studies (post-2010)
(uk 21)
Studies
(glycine)
Trials
(glycine)
Recent Studies (post-2010) (glycine)
50035,1637568,415

Protein Interaction Comparison

ProteinTaxonomyuk 21 (IC50)glycine (IC50)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)1.4852
Sodium- and chloride-dependent glycine transporter 1Homo sapiens (human)106
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)0.3253
Sodium- and chloride-dependent glycine transporter 2Homo sapiens (human)128

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kato, T; Kitaichi, K; Koda, A; Mori, H; Sakamoto, O1
Kaku, Y; Kita, J; Koda, A; Maeda, D; Mori, H; Nagai, H; Nakayama, K1
Kitaichi, K; Koda, A; Mori, H; Sakamoto, O1
Abe, K; Hanafi, M; Shibata, K; Tanaka, T; Taniguchi, M; Ueki, M1
Ishida, R; Ito, S; Koda, A; Mori, H; Nagai, H; Nakayama, K1

Other Studies

5 other study(ies) available for uk 21 and glycine

ArticleYear
Antitumor activity of two novel low immunosuppressive fluoropyrimidines UK-21 and UK-25.
    Japanese journal of pharmacology, 1992, Volume: 59, Issue:4

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Body Weight; Fluorouracil; Glycine; Leukemia L1210; Leukemia P388; Lung Neoplasms; Methylcholanthrene; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Neoplasms, Experimental; Organ Size; Sarcoma 180; Spleen; Tegafur; Thymus Gland; Uridine

1992
Novel lowly immunosuppressive antitumor fluorouridine derivative, UK-21: antitumor activity and effect on humoral immune response in mice.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34, Issue:3

    Topics: Analysis of Variance; Animals; Antibody Formation; Antineoplastic Agents; Carcinoma; Female; Glycine; Immunosuppressive Agents; Leukemia, Experimental; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Uridine

1994
Novel low immunosuppressive derivatives of the antitumor drug fluoropyrimidine, UK-21 and UK-25: effect on delayed type hypersensitivity and tumor immunity.
    Japanese journal of pharmacology, 1993, Volume: 61, Issue:3

    Topics: Animals; Antineoplastic Agents; Erythrocytes; Female; Fluorouracil; Glycine; Hypersensitivity, Delayed; Immunity; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Sheep; Spleen; Uridine

1993
UK-2A, B, C and D, novel antifungal antibiotics from Streptomyces sp. 517-02. I. Fermentation, isolation, and biological properties.
    The Journal of antibiotics, 1996, Volume: 49, Issue:7

    Topics: Animals; Antibiotics, Antineoplastic; Antifungal Agents; Cell Division; Fermentation; Glycine; Humans; Lactones; Mice; Microbial Sensitivity Tests; Oxygen Consumption; Pyridines; Saccharomyces cerevisiae; Streptomyces; Tumor Cells, Cultured; Uridine

1996
Irreversible cytotoxic effect of a novel lowly immunosuppressive antitumor fluorouridine derivative, UK-21.
    Anti-cancer drugs, 1997, Volume: 8, Issue:5

    Topics: Antimetabolites, Antineoplastic; Cell Cycle; Cell Survival; Flow Cytometry; Floxuridine; Fluorouracil; Glycine; Humans; Immunosuppressive Agents; KB Cells; Neoplastic Stem Cells; Thymidine; Uridine

1997