sauristolactam: lactam of 10-aminomethyl-3-hydroxy-4-methoxyphenanthrene-1-carboxylic acid isolated from Saururus cernuus; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Saururus | genus | [no description available] | Saururaceae | A plant family of the order Piperales, subclass Magnoliidae class Magnoliopsida. Members contain sauristolactam, and aristololactam BII.[MeSH] |
| ID Source | ID |
|---|---|
| PubMed CID | 131002 |
| CHEMBL ID | 512443 |
| MeSH ID | M0178113 |
| Synonym |
|---|
| 2-hydroxy-1-methoxy-5-methyldibenz(cd,f)indol-4(5h)-one |
| 128533-02-8 |
| dibenz(cd,f)indol-4(5h)-one, 2-hydroxy-1-methoxy-5-methyl- |
| sauristolactam |
| CHEMBL512443 |
| DTXSID80155921 |
| 2-hydroxy-1-methoxy-5-methyldibenzo[cd,f]indol-4(5h)-one |
| CS-0066103 |
| HY-118482 |
| 14-hydroxy-15-methoxy-10-methyl-10-azatetracyclo[7.6.1.02,7.012,16]hexadeca-1(16),2,4,6,8,12,14-heptaen-11-one |
| sauristolactam (saurolactam) |
| dibenz[cd,f]indol-4(5h)-one, 2-hydroxy-1-methoxy-5-methyl- |
| 14-hydroxy-15-methoxy-10-methyl-10-azatetracyclo[7.6.1.0?,?.0??,??]hexadeca-1(16),2(7),3,5,8,12,14-heptaen-11-one |
| AKOS040742614 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID351331 | Antiproliferative activity against multidrug resistant human HCT15/CLO2 cells by SRB assay | 2009 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 19, Issue:11 | Synthesis of aristolactam analogues and evaluation of their antitumor activity. |
| AID351329 | Antiproliferative activity against multidrug resistant human MES-SA/Dx5 cells by SRB assay | 2009 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 19, Issue:11 | Synthesis of aristolactam analogues and evaluation of their antitumor activity. |
| AID351330 | Antiproliferative activity against human HCT15 cells by SRB assay | 2009 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 19, Issue:11 | Synthesis of aristolactam analogues and evaluation of their antitumor activity. |
| AID351328 | Antiproliferative activity against human MESSA cells by SRB assay | 2009 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 19, Issue:11 | Synthesis of aristolactam analogues and evaluation of their antitumor activity. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.87) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (16.67%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (83.33%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||