Page last updated: 2024-12-07
sauristolactam
Description
sauristolactam: lactam of 10-aminomethyl-3-hydroxy-4-methoxyphenanthrene-1-carboxylic acid isolated from Saururus cernuus; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Flora | Rank | Flora Definition | Family | Family Definition |
Saururus | genus | [no description available] | Saururaceae | A plant family of the order Piperales, subclass Magnoliidae class Magnoliopsida. Members contain sauristolactam, and aristololactam BII.[MeSH] |
Cross-References
ID Source | ID |
PubMed CID | 131002 |
CHEMBL ID | 512443 |
MeSH ID | M0178113 |
Synonyms (14)
Synonym |
2-hydroxy-1-methoxy-5-methyldibenz(cd,f)indol-4(5h)-one |
128533-02-8 |
dibenz(cd,f)indol-4(5h)-one, 2-hydroxy-1-methoxy-5-methyl- |
sauristolactam |
CHEMBL512443 |
DTXSID80155921 |
2-hydroxy-1-methoxy-5-methyldibenzo[cd,f]indol-4(5h)-one |
CS-0066103 |
HY-118482 |
14-hydroxy-15-methoxy-10-methyl-10-azatetracyclo[7.6.1.02,7.012,16]hexadeca-1(16),2,4,6,8,12,14-heptaen-11-one |
sauristolactam (saurolactam) |
dibenz[cd,f]indol-4(5h)-one, 2-hydroxy-1-methoxy-5-methyl- |
14-hydroxy-15-methoxy-10-methyl-10-azatetracyclo[7.6.1.0?,?.0??,??]hexadeca-1(16),2(7),3,5,8,12,14-heptaen-11-one |
AKOS040742614 |
Bioassays (4)
Assay ID | Title | Year | Journal | Article |
AID351331 | Antiproliferative activity against multidrug resistant human HCT15/CLO2 cells by SRB assay | 2009 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 19, Issue:11
| Synthesis of aristolactam analogues and evaluation of their antitumor activity. |
AID351329 | Antiproliferative activity against multidrug resistant human MES-SA/Dx5 cells by SRB assay | 2009 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 19, Issue:11
| Synthesis of aristolactam analogues and evaluation of their antitumor activity. |
AID351330 | Antiproliferative activity against human HCT15 cells by SRB assay | 2009 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 19, Issue:11
| Synthesis of aristolactam analogues and evaluation of their antitumor activity. |
AID351328 | Antiproliferative activity against human MESSA cells by SRB assay | 2009 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 19, Issue:11
| Synthesis of aristolactam analogues and evaluation of their antitumor activity. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (5)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (20.00) | 18.2507 |
2000's | 3 (60.00) | 29.6817 |
2010's | 1 (20.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.87
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
Metric | This Compound (vs All) |
---|
Research Demand Index | 12.87 (24.57) | Research Supply Index | 1.95 (2.92) | Research Growth Index | 4.82 (4.65) | Search Engine Demand Index | 0.00 (26.88) | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 1 (16.67%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (83.33%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |