Compounds > pentylone
Page last updated: 2024-11-13

pentylone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

pentylone: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID60208608
SCHEMBL ID17644174
MeSH IDM000599899

Synonyms (21)

Synonym
dea no. 7542
ign39wgh0q ,
beta-keto-methylbenzodioxolylpentanamine
nrg-3
bk-methyl-k
methylbenzodioxolylpentanamine
unii-ign39wgh0q
bk-mbdp
698963-77-8
pentylone
DFMLULIEUUXXSA-UHFFFAOYSA-N
1-pentanone, 1-(1,3-benzodioxol-5-yl)-2-(methylamino)-
1-(1,3-benzodioxol-5-yl)-2-(methylamino)pentan-1-one
J3.293.464A ,
SCHEMBL17644174
1-(benzo[d][1,3]dioxol-5-yl)-2-(methylamino)pentan-1-one
(+/-)-1-(1,3-benzodioxol-5-yl)-2-(methylamino)pentan-1-one
BCP21171
Q7165334
mfcd28015752
DTXSID401014183

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
" The pharmacokinetic profiles of the synthetic cathinones vary based on the substitutions to the core scaffold."( A review of the influence of functional group modifications to the core scaffold of synthetic cathinones on drug pharmacokinetics.
Calinski, DM; Kisor, DF; Sprague, JE, 2019)		0.51
"To provide a summary of the literature regarding the pharmacokinetic characteristics of the synthetic cathinones, with a focus on the impact of the structural modifications to the pharmacokinetics."( A review of the influence of functional group modifications to the core scaffold of synthetic cathinones on drug pharmacokinetics.
Calinski, DM; Kisor, DF; Sprague, JE, 2019)		0.51
"In many, but not all, instances the pharmacokinetic characteristics of the synthetic cathinones can be reasonably predicted based on the substitutions to the core scaffold."( A review of the influence of functional group modifications to the core scaffold of synthetic cathinones on drug pharmacokinetics.
Calinski, DM; Kisor, DF; Sprague, JE, 2019)		0.51
"Continued research will lead to a better understanding of the pharmacokinetic changes associated with structural modifications to the cathinone scaffold, and potentially in the long range, enhanced overdose and addiction therapy."( A review of the influence of functional group modifications to the core scaffold of synthetic cathinones on drug pharmacokinetics.
Calinski, DM; Kisor, DF; Sprague, JE, 2019)		0.51
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (62.50)24.3611
2020's3 (37.50)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 46.85

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index46.85 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.56 (4.65)
Search Engine Demand Index69.20 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (46.85)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (11.11%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (88.89%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
acetone
methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).		2.2510ketone body;
methyl ketone;
propanones;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
human metabolite;
polar aprotic solvent
3,4-methylenedioxyamphetamine
3,4-Methylenedioxyamphetamine: An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons and has been used for that purpose experimentally.		2.2110benzodioxoles
amphetamine
Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.. 1-phenylpropan-2-amine : A primary amine that is isopropylamine in which a hydrogen attached to one of the methyl groups has been replaced by a phenyl group.. amphetamine : A racemate comprising equimolar amounts of (R)-amphetamine (also known as levamphetamine or levoamphetamine) and (S)-amphetamine (also known as dexamfetamine or dextroamphetamine.		2.610primary amine
methamphetamine
Methamphetamine: A central nervous system stimulant and sympathomimetic with actions and uses similar to DEXTROAMPHETAMINE. The smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed.. methamphetamine : A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.		4.3850amphetamines;
secondary amine		central nervous system stimulant;
environmental contaminant;
neurotoxin;
psychotropic drug;
xenobiotic
cathinone
cathinone: alkaloid from khat shrub, Catha edulis; RN given refers to parent cpd without isomeric designation. cathinone : The S stereoisomer of 2-aminopropiophenone.		9.39502-aminopropiophenone;
monoamine alkaloid		central nervous system stimulant;
psychotropic drug
4-methoxymethcathinone
4-methoxymethcathinone: structure in first source		2.110
cocaine
Cocaine: An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.. cocaine : A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.		2.1110benzoate ester;
methyl ester;
tertiary amino compound;
tropane alkaloid		adrenergic uptake inhibitor;
central nervous system stimulant;
dopamine uptake inhibitor;
environmental contaminant;
local anaesthetic;
mouse metabolite;
plant metabolite;
serotonin uptake inhibitor;
sodium channel blocker;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
mephedrone
mephedrone: a beta-keto (bk) designer drug; Central Nervous System Stimulants. mephedrone : An aromatic ketone that is propiophenone substituted at C-4 and at C-beta with methyl and methylamino groups respectively. It is a synthetic stimulant and entactogen drug of the amphetamine and cathinone classes.		3.3110amphetamines;
aromatic ketone;
secondary amino compound		environmental contaminant;
xenobiotic
methylone
[no description available]		9.2240benzodioxoles
4-methylethcathinone
4-methylethcathinone: structure in first source		2.110aromatic ketone
buphedrone
buphedrone: structure in first source		2.110
3-fluoromethcathinone
3-fluoromethcathinone: structure in first source		2.110
2-methylamino-1-(3,4-methylenedioxyphenyl)butan-1-one
2-methylamino-1-(3,4-methylenedioxyphenyl)butan-1-one: Hallucinogen		2.2110butanone
2-ethylammonio-1-(3,4-methylenedioxyphenyl)propane-1-one chloride
2-ethylammonio-1-(3,4-methylenedioxyphenyl)propane-1-one chloride: structure in first source		2.2510
pentedrone
pentedrone: structure in first source		7.5320
ConditionIndicatedRelationship StrengthStudiesTrials
Chemical Dependence
[description not available]		03.1210
Substance-Related Disorders
Disorders related to substance use or abuse.		03.1210