pentafluoroethane profile

Pentafluoroethane, also known as R-125, is a colorless, odorless, and non-flammable gas. It is a synthetic compound used as a refrigerant, blowing agent, and propellant. Pentafluoroethane is produced through the fluorination of ethane or by the reaction of tetrafluoroethylene with hydrogen fluoride. Its primary use is as a refrigerant in refrigeration and air conditioning systems, due to its high refrigerating capacity and low global warming potential compared to some other refrigerants. It is also used as a blowing agent in the production of foams, and as a propellant in aerosols. Studies on pentafluoroethane often focus on its environmental impact, including its atmospheric lifetime and contribution to global warming. Researchers investigate its potential use in sustainable refrigerants and the development of alternative technologies to reduce its environmental footprint.'

ID Source	ID
PubMed CID	9633
SCHEMBL ID	5439
MeSH ID	M0209827

Synonym
ethane, pentafluoro-
c2f5h
khladon 125
un3220
hcfc 125
hfc 125
fc 125
einecs 206-557-8
fron 125
r 125
hsdb 6755
ccris 7630
1,1,2,2,2-pentafluoroethane
hfc-125
inchi=1/c2hf5/c3-1(4)2(5,6)7/h1
1,1,1,2,2-pentafluoroethane
354-33-6
pentafluoroethane
FT-0658782
AKOS006230211
ecolo ace 125
hfa 125
ethane, 1,1,1,2,2-pentafluoro-
pentafluoroethane or refrigerant gas r 125 [un3220] [nonflammable gas]
ec 206-557-8
pentafluoroethane or refrigerant gas r 125
hfo 125
unii-6tq8593lrq
6tq8593lrq ,
freon 125
SCHEMBL5439
chf2cf3
pentafluoroethane [hsdb]
fc-125
r-125
genetron hfc 125
DTXSID1024251
mfcd00042101
pentafluoroethane 99%
Q419065
AMY37170
ethyl, 1,1,2,2,2-pentafluoro-

Excerpt	Reference	Relevance
" The acute toxic endpoint of concern for these agents is cardiac sensitization."	( Setting safe acute exposure limits for halon replacement chemicals using physiologically based pharmacokinetic modeling. Brock, WJ; Cisneros, M; Jepson, GW; Rubenstein, R; Vinegar, A, 2000)	0.31

Excerpt	Reference	Relevance
" Linkage was made using a physiologically based pharmacokinetic (PBPK) model."	( Setting safe acute exposure limits for halon replacement chemicals using physiologically based pharmacokinetic modeling. Brock, WJ; Cisneros, M; Jepson, GW; Rubenstein, R; Vinegar, A, 2000)	0.31

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	2 (11.76)	18.2507
2000's	5 (29.41)	29.6817
2010's	9 (52.94)	24.3611
2020's	1 (5.88)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	2 (11.11%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	16 (88.89%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
1-butanol 1-Butanol: A four carbon linear hydrocarbon that has a hydroxy group at position 1.. butan-1-ol : A primary alcohol that is butane in which a hydrogen of one of the methyl groups is substituted by a hydroxy group. It it produced in small amounts in humans by the gut microbes.	2.03	1	alkyl alcohol; primary alcohol; short-chain primary fatty alcohol	human metabolite; mouse metabolite; protic solvent
methanol Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.. primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.. methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.	2.31	1	alkyl alcohol; one-carbon compound; primary alcohol; volatile organic compound	amphiprotic solvent; Escherichia coli metabolite; fuel; human metabolite; mouse metabolite; Mycoplasma genitalium metabolite
2,2'-dipyridyl 2,2'-Dipyridyl: A reagent used for the determination of iron.. 2,2'-bipyridine : A bipyridine in which the two pyridine moieties are linked by a bond between positions C-2 and C-2'.	2.21	1	bipyridine	chelator; ferroptosis inhibitor
chloroform Chloroform: A commonly used laboratory solvent. It was previously used as an anesthetic, but was banned from use in the U.S. due to its suspected carcinogenicity.. chloroform : A one-carbon compound that is methane in which three of the hydrogens are replaced by chlorines.	2.03	1	chloromethanes; one-carbon compound	carcinogenic agent; central nervous system drug; inhalation anaesthetic; non-polar solvent; refrigerant
n-pentanol n-pentanol: RN given refers to parent cpd. pentan-1-ol : A short-chain primary fatty alcohol that is pentane in which a hydrogen of one of the methyl groups is substituted by a hydroxy group. It has been isolated from Melicope ptelefolia.	2.03	1	pentanol; short-chain primary fatty alcohol	human metabolite; plant metabolite
bromotrifluoromethane [no description available]	2	1
trichlorofluoromethane trichlorofluoromethane: refrigerant, aerosol propellant; RN given refers to parent cpd; structure. trichlorofluoromethane : A one-carbon compound that is methane in which the hydrogens have been replaced by three chlorine and one fluorine atom.	3.27	1	chlorofluorocarbon; halomethane	environmental contaminant; NMR chemical shift reference compound; NMR solvent; refrigerant
dichlorodifluoromethane dichlorodifluoromethane: refrigerant,aerosol propellant	3.27	1
tetrafluoromethane tetrafluoromethane: structure in first source	2.06	1	fluorocarbon; fluoromethanes	refrigerant
1,1,2-trichloro-1,2,2-trifluoroethane [no description available]	3.27	1	chlorofluorocarbon; haloalkane	NMR solvent; refrigerant
freon 114 Freon 114: InChIKey: DDMOUSALMHHKOS-UHFFFAOYSA-N	3.27	1
2-butanol 2-butanol: RN given is for parent cpd without isomeric designation. butan-2-ol : A secondary alcohol that is butane substituted by a hydroxy group at position 2.	2.03	1	secondary alcohol
octafluorocyclobutane perfluorocyclobutane: structure in first source. octafluorocyclobutane : A fluorocarbon that is cyclobutane in which all eight hydrogens are replaced by fluorines.	2.06	1	cyclobutanes; fluorocarbon	food packaging gas; food propellant
hexafluoropropene [no description available]	2.06	1
2,2-dichloro-1,1,1-trifluoroethane 2,2-dichloro-1,1,1-trifluoroethane: structure given in first source. hydrochlorofluorocarbon : An organochlorine compound derived from methane, ethane or propane that contains atoms of hydrogen, chlorine, fluorine, and carbon only.	4.05	2
1,1,1-trichloro-2,2,2-trifluoroethane [no description available]	3.27	1
1,1,1-trifluoroethane [no description available]	8.6	2
norflurane norflurane: may replace R 12 as air-conditioning refrigerant; structure given in first source	3.6	2
1,1-dichloro-1-fluoroethane [no description available]	4.05	2
trifluoroiodomethane [no description available]	2.42	2
sulfur hexafluoride Sulfur Hexafluoride: Sulfur hexafluoride. An inert gas used mainly as a test gas in respiratory physiology. Other uses include its injection in vitreoretinal surgery to restore the vitreous chamber and as a tracer in monitoring the dispersion and deposition of air pollutants.. sulfur hexafluoride : A sulfur coordination entity consisting of six fluorine atoms attached to a central sulfur atom. It is the most potent greenhouse gas currently known, with a global warming potential of 23,900 times that of CO2 over a 100 year period (SF6 has an estimated lifetime in the atmosphere of between 800 and 3,000 years).	2.06	1	sulfur coordination entity	greenhouse gas; NMR chemical shift reference compound; ultrasound contrast agent
1,1,1,2-tetrafluoro-2-chloroethane 1,1,1,2-tetrafluoro-2-chloroethane: refrigerant	3.27	1
apaflurane [no description available]	2.44	2
1,1,1,3,3-pentafluoropropane [no description available]	8.6	2
1-butyl-3-methylimidazolium hexafluorophosphate 1-butyl-3-methylimidazolium hexafluorophosphate: structure in first source	2.03	1
2,3,3,3-tetrafluoropropene 2,3,3,3-tetrafluoropropene: structure in first source	3.27	1

Condition	Relationship Strength	Studies
Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	1.98	1
Abnormalities, Drug-Induced Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.	1.98	1
Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	1.98	1

pentafluoroethane

Cross-References

Synonyms (42)

Research Excerpts

Toxicity

Pharmacokinetics

Research

Studies (17)

Market Indicators

Research Demand Index: 49.69

Study Types