| Assay ID | Title | Year | Journal | Article |
|---|
| AID1246547 | Selectivity index, ratio of Ki for human 5HT1B receptor to Ki for human 5HT1F receptor | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19
| Discovery of selective N-[3-(1-methyl-piperidine-4-carbonyl)-phenyl]-benzamide-based 5-HT₁ F receptor agonists: Evolution from bicyclic to monocyclic cores. |
| AID1246546 | Selectivity index, ratio of Ki for human 5HT1A receptor to Ki for human 5HT1F receptor | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19
| Discovery of selective N-[3-(1-methyl-piperidine-4-carbonyl)-phenyl]-benzamide-based 5-HT₁ F receptor agonists: Evolution from bicyclic to monocyclic cores. |
| AID238743 | In vitro binding affinity for human 5-hydroxytryptamine 1F receptor | 2004 | Bioorganic & medicinal chemistry letters, Dec-20, Volume: 14, Issue:24
| Design, synthesis and evaluation of bicyclic benzamides as novel 5-HT1F receptor agonists. |
| AID4985 | In vitro binding affinity for human 5-hydroxytryptamine 1F receptor | 2004 | Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
| Substituted furo[3,2-b]pyridines: novel bioisosteres of 5-HT 1F receptor agonists. |
| AID404703 | Displacement of [3H]5-hydroxytryptamine from human cloned 5HT1D receptor expressed in CHOK1 cells by liquid scintillation counting | 2008 | Journal of medicinal chemistry, Jun-26, Volume: 51, Issue:12
| Designing selective, high affinity ligands of 5-HT1D receptor by covalent dimerization of 5-HT1F ligands derived from 4-fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]benzamide. |
| AID233111 | Ratio of the Ki value for human 5-HT1A receptor versus human 5-HT1F receptor | 2004 | Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
| Substituted furo[3,2-b]pyridines: novel bioisosteres of 5-HT 1F receptor agonists. |
| AID4986 | In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor | 2003 | Journal of medicinal chemistry, Jul-03, Volume: 46, Issue:14
| Novel potent 5-HT(1F) receptor agonists: structure-activity studies of a series of substituted N-[3-(1-methyl-4-piperidinyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]amides. |
| AID233112 | Ratio of the Ki value for human 5-HT1B receptor versus human 5-HT1F receptor | 2004 | Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
| Substituted furo[3,2-b]pyridines: novel bioisosteres of 5-HT 1F receptor agonists. |
| AID54913 | Inhibition of cytochrome P450 3A4 | 2002 | Bioorganic & medicinal chemistry letters, Feb-11, Volume: 12, Issue:3
| A neural network based virtual screening of cytochrome P450 3A4 inhibitors. |
| AID3848 | In vitro binding affinity by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1A receptor | 2003 | Journal of medicinal chemistry, Jul-03, Volume: 46, Issue:14
| Novel potent 5-HT(1F) receptor agonists: structure-activity studies of a series of substituted N-[3-(1-methyl-4-piperidinyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]amides. |
| AID238741 | In vitro binding affinity for human 5-hydroxytryptamine 1B receptor | 2004 | Bioorganic & medicinal chemistry letters, Dec-20, Volume: 14, Issue:24
| Design, synthesis and evaluation of bicyclic benzamides as novel 5-HT1F receptor agonists. |
| AID404702 | Displacement of [3H]5-hydroxytryptamine from human cloned 5HT1B receptor expressed in CHOK1 cells by liquid scintillation counting | 2008 | Journal of medicinal chemistry, Jun-26, Volume: 51, Issue:12
| Designing selective, high affinity ligands of 5-HT1D receptor by covalent dimerization of 5-HT1F ligands derived from 4-fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]benzamide. |
| AID1246548 | Selectivity index, ratio of Ki for human 5HT1D receptor to Ki for human 5HT1F receptor | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19
| Discovery of selective N-[3-(1-methyl-piperidine-4-carbonyl)-phenyl]-benzamide-based 5-HT₁ F receptor agonists: Evolution from bicyclic to monocyclic cores. |
| AID4254 | In vitro binding affinity by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1B receptor | 2003 | Journal of medicinal chemistry, Jul-03, Volume: 46, Issue:14
| Novel potent 5-HT(1F) receptor agonists: structure-activity studies of a series of substituted N-[3-(1-methyl-4-piperidinyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]amides. |
| AID238740 | In vitro binding affinity for human 5-hydroxytryptamine 1A receptor | 2004 | Bioorganic & medicinal chemistry letters, Dec-20, Volume: 14, Issue:24
| Design, synthesis and evaluation of bicyclic benzamides as novel 5-HT1F receptor agonists. |
| AID1246539 | Binding affinity to human 5HT1F receptor by radioligand binding assay | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19
| Discovery of selective N-[3-(1-methyl-piperidine-4-carbonyl)-phenyl]-benzamide-based 5-HT₁ F receptor agonists: Evolution from bicyclic to monocyclic cores. |
| AID233113 | Ratio of the Ki value for human 5-HT1D receptor versus human 5-HT1F receptor | 2004 | Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
| Substituted furo[3,2-b]pyridines: novel bioisosteres of 5-HT 1F receptor agonists. |
| AID1246538 | Binding affinity to 5HT1A receptor (unknown origin) | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19
| Discovery of selective N-[3-(1-methyl-piperidine-4-carbonyl)-phenyl]-benzamide-based 5-HT₁ F receptor agonists: Evolution from bicyclic to monocyclic cores. |
| AID4625 | In vitro binding affinity by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1D receptor | 2003 | Journal of medicinal chemistry, Jul-03, Volume: 46, Issue:14
| Novel potent 5-HT(1F) receptor agonists: structure-activity studies of a series of substituted N-[3-(1-methyl-4-piperidinyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]amides. |
| AID404716 | Selectivity for rhesus monkey 5HT1F receptor over human 5HT1D receptor | 2008 | Journal of medicinal chemistry, Jun-26, Volume: 51, Issue:12
| Designing selective, high affinity ligands of 5-HT1D receptor by covalent dimerization of 5-HT1F ligands derived from 4-fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]benzamide. |
| AID404717 | Binding affinity at human 5HT1F receptor | 2008 | Journal of medicinal chemistry, Jun-26, Volume: 51, Issue:12
| Designing selective, high affinity ligands of 5-HT1D receptor by covalent dimerization of 5-HT1F ligands derived from 4-fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]benzamide. |
| AID404704 | Displacement of [3H]5-hydroxytryptamine from rhesus monkey cloned 5HT1F receptor expressed in African green monkey COS7 cells by liquid scintillation counting | 2008 | Journal of medicinal chemistry, Jun-26, Volume: 51, Issue:12
| Designing selective, high affinity ligands of 5-HT1D receptor by covalent dimerization of 5-HT1F ligands derived from 4-fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]benzamide. |
| AID404715 | Selectivity for rhesus monkey 5HT1F receptor over human 5HT1B receptor | 2008 | Journal of medicinal chemistry, Jun-26, Volume: 51, Issue:12
| Designing selective, high affinity ligands of 5-HT1D receptor by covalent dimerization of 5-HT1F ligands derived from 4-fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]benzamide. |
| AID238742 | In vitro binding affinity for human 5-hydroxytryptamine 1D receptor | 2004 | Bioorganic & medicinal chemistry letters, Dec-20, Volume: 14, Issue:24
| Design, synthesis and evaluation of bicyclic benzamides as novel 5-HT1F receptor agonists. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346739 | Human 5-HT1F receptor (5-Hydroxytryptamine receptors) | 2005 | Naunyn-Schmiedeberg's archives of pharmacology, Mar, Volume: 371, Issue:3
| [3H]LY334370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties. |
| AID624233 | Agonists at Human 5-Hydroxytryptamine receptor 5-HT1F | 2005 | Naunyn-Schmiedeberg's archives of pharmacology, Mar, Volume: 371, Issue:3
| [3H]LY334370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties. |
| AID624210 | Agonists at Human 5-Hydroxytryptamine receptor 5-HT1A | 2005 | Naunyn-Schmiedeberg's archives of pharmacology, Mar, Volume: 371, Issue:3
| [3H]LY334370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties. |
| AID1345615 | Human 5-HT1A receptor (5-Hydroxytryptamine receptors) | 2005 | Naunyn-Schmiedeberg's archives of pharmacology, Mar, Volume: 371, Issue:3
| [3H]LY334370, a novel radioligand for the 5-HT1F receptor. I. In vitro characterization of binding properties. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |