halosulfuron methyl

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

halosulfuron methyl: an herbicide; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Flora	Rank	Flora Definition	Family	Family Definition
Sandea	genus	[no description available]	Conocephalaceae	[no description available]

Cross-References

ID Source	ID
PubMed CID	91763
CHEMBL ID	2140532
CHEBI ID	81750
SCHEMBL ID	55094
MeSH ID	M0525564

Synonyms (56)

Synonym
AC-18023
battalion
inpool
halosulfuron-methyl [iso:bsi]
permit 75wg
sempra
a 841101
nc 319
mon 12000
nc 311
sandea
1h-pyrazole-4-carboxylic acid, 3-chloro-5-(((((4,6-dimethoxy-2-pyrimidinyl)amino)carbonyl)amino)sulfonyl)-1-methyl-, methyl ester
NCGC00163811-01
100784-20-1
methyl 3-chloro-5-({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]amino}sulfonyl)-1-methyl-1h-pyrazole-4-carboxylate
halosulfuron-methyl
NCGC00163811-02
methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate
halosulfuron methyl
C18442
H1374
3-chloro-5-[[3-(4,6-dimethoxypyrimidin-2-yl)ureido]sulfonyl]-1-methyl-1h-pyrazole-4-carboxylic acid methyl ester
methyl 3-chloro-5-[[3-(4,6-dimethoxypyrimidin-2-yl)ureido]sulfonyl]-1-methyl-1h-pyrazole-4-carboxylate
unii-w1cp17gd87
w1cp17gd87 ,
FT-0642433
AKOS015900285
SCHEMBL55094
manage (monsanto)
methyl 3-chloro-5-(4,6-dimethoxypyrimidin-2-ylcarbamoylsulfamoyl)-1-methylpyrazole-4-carboxylate
permit (nissan)
halosulfuron-methyl [mi]
mon-12037
nc-319
halosulfuron methyl ester
mon-12000
3-chloro-5-(((((4,6-dimethoxy-2-pyrimidinyl)amino)carbonyl)amino)sulfonyl)-1-methyl-1h-pyrazole-4-carboxylic acid methyl ester
halosulfuron-methyl [iso]
CHEBI:81750 ,
CHEMBL2140532
1h-pyrazole-4-carboxylic acid, 3-chloro-5-[[[[(4,6-dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]-1-methyl-, methyl ester
FMGZEUWROYGLAY-UHFFFAOYSA-N
DTXSID9034650
J-000222
halosulfuron-methyl, pestanal(r), analytical standard
halosulfuron-methyl, bsi
mfcd01631160
methyl 3-chloro-5-(n-(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl)-1-methyl-1h-pyrazole-4-carboxylate
halosulfuron methyl ,3-chloro-5-(((((4,6-dimethoxy-2-pyrimidinyl)amino)carbonyl)amino)sulfonyl)-1-methyl-1h-pyrazole-4-carboxylic acid methyl ester
Q22808250
halosulfuron-methyl 100 microg/ml in acetonitrile
AS-15266
methyl 3-chloro-5-(n-((4,6-dimethoxypyrimidin-2-yl)carbamoyl)sulfamoyl)-1-methyl-1h-pyrazole-4-carboxylate
AMY3556
a-841101
T71523

Research Excerpts

Overview

Halosulfuron methyl (HSM) is a herbicide widely used to control sedge and broad-leaved weeds during crop production. Its environmental residue may damage non-target crops.

Excerpt	Reference	Relevance
"Halosulfuron methyl (HM) is a new, highly active sulfonylurea herbicide that has been widely used for weed control in agricultural production. "	( Halosulfuron methyl did not have a significant effect on diversity and community of sugarcane rhizosphere microflora. Du, L; Huang, M; Huang, S; Jin, D; Liu, H; Long, D; Wang, Y, 2020)	3.44
"Halosulfuron methyl (HSM) is a herbicide widely used to control sedge and broad-leaved weeds during crop production, but its environmental residue may damage non-target crops. "	( Integrated proteomics, metabolomics and physiological analyses for dissecting the toxic effects of halosulfuron-methyl on soybean seedlings (Glycine max merr.). Li, X; Li, Y; Tan, H; Yu, Y; Zhang, Q, 2020)	2

Dosage Studied

Excerpt	Relevance	Reference
" Cross resistance of HB08 and HB16 to AHAS herbicides of SU, imidazolinone (IMI), triazolopyrimidine (TP) and pyrimidinyl-thiobenozoate (PTB) families was investigated by dose-response experiments."	( Different cross-resistance patterns to AHAS herbicides of two tribenuron-methyl resistant flixweed (Descurainiasophia L.) biotypes in China. Cao, Y; Deng, W; Liu, MJ; Mei, Y; Yang, Q; Zheng, MQ, 2014)	0.4

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

Class	Description
pyrazoles
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (1)

Potency Measurements

Protein	Taxonomy	Measurement	Average (µ)	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
nuclear factor erythroid 2-related factor 2 isoform 1	Homo sapiens (human)	Potency	76.9588	0.0006	27.2152	1,122.0200	AID651741
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (15)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (6.67)	29.6817
2010's	9 (60.00)	24.3611
2020's	5 (33.33)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 38.19

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	38.19 (24.57)
Research Supply Index	2.77 (2.92)
Research Growth Index	5.26 (4.65)
Search Engine Demand Index	95.21 (26.88)
Search Engine Supply Index	3.84 (0.95)

This Compound (38.19)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	15 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
salicylic acid Scalp: The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendinous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL).	2.15	1	monohydroxybenzoic acid	algal metabolite; antifungal agent; antiinfective agent; EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor; keratolytic drug; plant hormone; plant metabolite
ethylene Plastipore: high density polyethylene sponge biocompatible material; used as posts in dental bridges	2.15	1	alkene; gas molecular entity	plant hormone; refrigerant
malondialdehyde Malondialdehyde: The dialdehyde of malonic acid.. malonaldehyde : A dialdehyde that is propane substituted by two oxo groups at the terminal carbon atoms respectively. A biomarker of oxidative damage to lipids caused by smoking, it exists in vivo mainly in the enol form.	2.15	1	dialdehyde	biomarker
phenyl acetate phenyl acetate: The ester formed between phenol and acetic acid. Don't confuse with phenylacetic acid derivatives listed under PHENYLACETATES.. phenyl acetate : An acetate ester obtained by the formal condensation of phenol with acetic acid.	2.31	1	benzenes; phenyl acetates
4,5-amino-3,5-dichloro-6-fluoro-2-pyridinyloxyacetic acid fluroxypyr : An aminopyridine that is pyridin-4-amine substituted by chloro groups at positions 3 and 5, a fluoro group at position 6 and a carboxymethoxy group at position 2.	2.31	1	aminopyridine; aromatic ether; monocarboxylic acid; organochlorine compound; organofluorine compound	environmental contaminant; herbicide; xenobiotic
metsulfuron methyl metsulfuron methyl : A N-sulfonylurea in which the sulfonyl group is attached to a 2-(methoxycarbonyl)phenyl group while a (4-methoxy-6-methyl-1,3,5-triazin-2-yl group replaces one of the amino hydrogens of the remaining urea group.	2.1	1	1,3,5-triazines; benzoate ester; N-sulfonylurea	environmental contaminant; herbicide; xenobiotic
triazoles Triazoles: Heterocyclic compounds containing a five-membered ring with two carbon atoms and three nitrogen atoms with the molecular formula C2H3N3.. triazoles : An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms.	2.1	1	1,2,3-triazole
triasulfuron triasulfuron : An N-sulfonylurea that is N-[o-(2-chloroethoxy)phenyl]sulfonylurea in which one of the hydrogens attached to the non-sulfonylated nitrogen has been replaced by a 4-methoxy-6-methyl-1,3,5-triazin-2-yl group. A herbicide used to control broad-leaved weeds in cereals, its use within the EU has been banned after September 2017 on the grounds of potential groundwater contamination and risks to aquatic life.	2.1	1	1,3,5-triazines; aromatic ether; N-sulfonylurea; organochlorine compound	agrochemical; herbicide
ethyl 5-(4,6-dimethoxypyrimidin-2-ylcarbamoylsulfamoyl)-1-methylpyrazole-4-carboxylate ethyl 5-(4,6-dimethoxypyrimidin-2-ylcarbamoylsulfamoyl)-1-methylpyrazole-4-carboxylate: structure in first source	2.04	1	pyrazoles
prizes acetamiprid: structure in first source. (E)-acetamiprid : The (E)-stereoisomer of acetamiprid.. acetamiprid : A carboxamidine that is acetamidine in which the amino hydrogens are substituted by a (6-chloropyridin-3-yl)methyl and a methyl group while the hydrogen attached to the imino nitrogen is replaced by a cyano group.	2.15	1	carboxamidine; monochloropyridine; nitrile	environmental contaminant; neonicotinoid insectide; xenobiotic
1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethoxyphenoxysulfonyl)urea 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethoxyphenoxysulfonyl)urea: herbicide; structure in first source	2.17	1	aromatic ether
mesosulfuron-methyl mesosulfuron-methyl: an herbicide	2.17	1
chlorophyll a Chlorophyll: Porphyrin derivatives containing magnesium that act to convert light energy in photosynthetic organisms.. chlorophyll : A family of magnesium porphyrins, defined by the presence of a fifth ring beyond the four pyrrole-like rings. The rings can have various side chains which usually include a long phytol chain.	2.15	1	chlorophyll; methyl ester	cofactor
pheophytin a pheophytin a: structure given in first source; RN given refers to (3S-(3alpha(2E,7S,11S),4beta,21beta))-isomer	2.25	1

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