Compounds > delta7-dafachronic acid
Page last updated: 2024-11-13

delta7-dafachronic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

delta7-dafachronic acid: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

(25S)-Delta(7)-dafachronic acid : A Delta(7)-dafachronic acid that has S configuration at position 25 (the carbon attached to the carboxy group). [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID23583984
CHEBI ID71556
MeSH IDM0527818

Synonyms (29)

Synonym
c27h42o3
(5beta,14beta,17alpha,25s)-3-oxocholest-7-en-26-oic acid
d7s ,
CHEBI:71556
(25s)-delta(7)-dafachronic acid
(+)-(25s)-3-oxo-5alpha-cholest-7-en-26-oic acid
949004-12-0
(+)-(25s)-3-keto-5alpha-cholest-7-en-26-oic acid
(+)-(5alpha,25s)-3-oxocholest-7-en-26-oic acid
(25s)-3-oxo-5alpha-cholest-7-en-26-oic acid
(25s)-3-keto-5alpha-cholest-7-en-26-oic acid
(25s),26-3-keto-7-cholestenoic acid
(5alpha,25s)-3-oxocholest-7-en-26-oic acid
LMST04030222
(25s)-3-oxocholest-7-en-26-oic acid
(25s)-delta7-dafachronic acid
(5?,25s)-3-oxo-cholest-7-en-26-oic acid
HB3693
C21077
delta7-dafachronic acid
3-keto-7,(5alpha)-cholestenoic acid
(5|a,25s)-3-oxocholest-7-en-26-oic acid
Q27139706
(5alpha,25s)-3-oxo-cholest-7-en-26-oicacid
(2s,6r)-6-[(5s,9r,10s,13r,14r,17r)-10,13-dimethyl-3-oxo-1,2,4,5,6,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-methylheptanoic acid
(5alpha,25s)-3-oxo-cholest-7-en-26-oic acid
DTXSID601284427
(25s)-?7-dafachronic acid
AKOS040747618
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
Caenorhabditis elegans metaboliteA nematode metabolite produced by Caenorhabditis elegans.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
Delta(7)-dafachronic acidA member of the class of dafachronic acids that is (5alpha)-3-oxocholest-7-ene in which the methyl group at position 26 has been oxidised to the correponding carboxylic acid. Found in Caenorhabditis elegans.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (1)

PathwayProteinsCompounds
Dauer formation02

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's8 (72.73)24.3611
2020's1 (9.09)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.61

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.61 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index5.10 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.61)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source		2.0810chromones;
morpholines;
organochlorine compound		autophagy inhibitor;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
geroprotector
methylprednisolone acetate
Methylprednisolone Acetate: Methylprednisolone derivative that is used as an anti-inflammatory agent for the treatment of ALLERGY and ALLERGIC RHINITIS; ASTHMA; and BURSITIS; and for the treatment of ADRENAL INSUFFICIENCY.. methylprednisolone acetate : An acetate ester resulting from the formal condensation of the 21-hydroxy function of 6alpha-methylprednisolone compound with acetic acid.		2.171011beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
acetate ester;
glucocorticoid;
steroid ester;
tertiary alpha-hydroxy ketone		anti-inflammatory drug
methylprednisolone
Methylprednisolone: A PREDNISOLONE derivative with similar anti-inflammatory action.. 6alpha-methylprednisolone : The 6alpha-stereoisomer of 6-methylprednisolone.		2.17106-methylprednisolone;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		adrenergic agent;
anti-inflammatory drug;
antiemetic;
environmental contaminant;
neuroprotective agent;
xenobiotic
isoxazoles
Isoxazoles: Azoles with an OXYGEN and a NITROGEN next to each other at the 1,2 positions, in contrast to OXAZOLES that have nitrogens at the 1,3 positions.. isoxazole : A monocyclic heteroarene with a structure consisting of a 5-membered ring containing three carbon atoms and an oxygen and nitrogen atom adjacent to each other. It is the parent of the class of isoxazoles.. isoxazoles : Oxazoles in which the N and O atoms are adjacent.		2.2110isoxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
ergosterol
[no description available]		2.04103beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
ergostanoid;
phytosterols		fungal metabolite;
Saccharomyces cerevisiae metabolite
delta4-dafachronic acid
delta4-dafachronic acid: structure in first source. Delta(4)-dafachronic acid : A cholestanoid that is cholest-4-en-26-oic acid which is substituted at position 3 by an oxo group.		8403-oxo-Delta(4) steroid;
C27-steroid;
dafachronic acids
3-hydroxy-5-cholestenoic acid, (3beta,25r)-isomer
cholestenoic acid: structure in first source. (25R)-3beta-hydroxycholest-5-en-26-oic acid : A 3beta-hydroxycholest-5-en-26-oic acid in which the stereocentre at position 25 has R-configuration.		2.04103beta-hydroxycholest-5-en-26-oic acid
piperidines
Piperidines: A family of hexahydropyridines.		2.2110
dafachronic acid
dafachronic acid: structure in first source. (5alpha)-3-oxocholestan-26-oic acid : A cholestanoid that is (5alpha)-cholestan-26-oic acid in which the hydrogens at position 3 are replaced by an oxo group.		7.04103-oxo-5alpha-steroid;
cholestanoid;
dafachronic acids
ConditionIndicatedRelationship StrengthStudiesTrials
Anguilluliasis
[description not available]		02.1710
Strongyloidiasis
Infection with nematodes of the genus STRONGYLOIDES. The presence of larvae may produce pneumonitis and the presence of adult worms in the intestine could lead to moderate to severe diarrhea.		02.1710
Ovine Diseases
[description not available]		02.2110
Haemonchiasis
Infection with nematodes of the genus HAEMONCHUS, characterized by digestive abnormalities and anemia similar to that from hookworm infestation.		02.2110