dafachronic acids

Any of a family of steroid acids derived from sterols by oxidation with a cytochrome p450 that bind and activate the orphan nuclear receptor DAF-12 in the nematode Caenorhabditis elegans. Note that the singular term 'dafachronic acid' has been used as a synonym for the (non-natural) fully saturated (5alpha,25S)-3-oxocholestan-26-oic acid.

ChEBI ID: 78698

Members (2)

Member	Definition	Role
dafachronic acid	A cholestanoid that is (5alpha)-cholestan-26-oic acid in which the hydrogens at position 3 are replaced by an oxo group.	(5alpha)-3-oxocholestan-26-oic acid
delta4-dafachronic acid	A cholestanoid that is cholest-4-en-26-oic acid which is substituted at position 3 by an oxo group.	Delta(4)-dafachronic acid

Research

Studies (41)

Timeframe	Studies, Drugs in This Class (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	7 (17.07)	29.6817
2010's	29 (70.73)	24.3611
2020's	5 (12.20)	2.80

Study Types

Publication Type	Studies, Drugs in This Class (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	2 (4.65%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	41 (95.35%)	84.16%