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dafachronic acids
Any of a family of steroid acids derived from sterols by oxidation with a cytochrome p450 that bind and activate the orphan nuclear receptor DAF-12 in the nematode Caenorhabditis elegans. Note that the singular term 'dafachronic acid' has been used as a synonym for the (non-natural) fully saturated (5alpha,25S)-3-oxocholestan-26-oic acid.
ChEBI ID: 78698
Members (2)
| Member | Definition | Role |
|---|---|---|
| dafachronic acid | A cholestanoid that is (5alpha)-cholestan-26-oic acid in which the hydrogens at position 3 are replaced by an oxo group. | (5alpha)-3-oxocholestan-26-oic acid |
| delta4-dafachronic acid | A cholestanoid that is cholest-4-en-26-oic acid which is substituted at position 3 by an oxo group. | Delta(4)-dafachronic acid |
Research
Studies (41)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (17.07) | 29.6817 |
| 2010's | 29 (70.73) | 24.3611 |
| 2020's | 5 (12.20) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 2 (4.65%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 41 (95.35%) | 84.16% |