ck-0944666 has been researched along with fura-2-am* in 1 studies
1 other study(ies) available for ck-0944666 and fura-2-am
| Article | Year |
|---|---|
Involvement of the Arp2/3 complex and WASP proteins in the effect of glutoxim and molixan on intracellular Ca(2+) concentration in macrophages.
The Fura-2AM fluorescent Ca(2+) probe was used to study the possibility that the Arp2/3 complex and WASP proteins are involved in the effects of glutoxim and molixan on the intracellular Ca(2+) concentration in macrophages. It has been demonstrated that preincubation of macrophages with inhibitors of the Arp2/3 complex or WASP proteins (CK-0944666 or wiskostatin, respectively) results in a significant suppression of Ca(2+)-responses induced by glutoxim or molixan. This suggests that polymerization of actin filaments is a process involved in the effect of glutoxim or molixan on intracellular Ca(2+) concentration in macrophages. Topics: Actin-Related Protein 2-3 Complex; Animals; Calcium; Carbazoles; Cations, Divalent; Cells, Cultured; Drug Combinations; Fluorescent Dyes; Fura-2; Glutathione; Indoles; Inosine; Macrophages, Peritoneal; Oligopeptides; Propanolamines; Rats, Wistar; Voltage-Sensitive Dye Imaging; Wiskott-Aldrich Syndrome Protein Family | 2015 |