| Assay ID | Title | Year | Journal | Article |
|---|
| AID164934 | Compound was evaluated for the inhibitory activity against purine nucleoside phosphorylase (PNP) as a function of time of dialysis after 24 hours at 5 uM concentration | 1992 | Journal of medicinal chemistry, May-01, Volume: 35, Issue:9
| Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th |
| AID164932 | Compound was evaluated for the inhibitory activity against purine nucleoside phosphorylase (PNP) as a function of time of dialysis after 0 hours at 5 uM concentration | 1992 | Journal of medicinal chemistry, May-01, Volume: 35, Issue:9
| Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th |
| AID223844 | Compound was evaluated for the inhibitory activity against purine nucleoside phosphorylase (PNP) as a function of time of dialysis after 6 hours at 5 uM concentration | 1992 | Journal of medicinal chemistry, May-01, Volume: 35, Issue:9
| Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th |
| AID23553 | Solubility in water | 1992 | Journal of medicinal chemistry, May-01, Volume: 35, Issue:9
| Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th |
| AID164912 | Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP) | 1992 | Journal of medicinal chemistry, May-01, Volume: 35, Issue:9
| Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th |
| AID164920 | Ability to inhibit purine nucleoside phosphorylase (PNP) | 1992 | Journal of medicinal chemistry, May-01, Volume: 35, Issue:9
| Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th |
| AID105654 | Compound was tested for the cytotoxic activity against MOLT-4 lymphoblasts | 1992 | Journal of medicinal chemistry, May-01, Volume: 35, Issue:9
| Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th |
| AID16054 | Apparent bioavailability in dogs at 15 mg/kg in an iv vs po dosing regimen | 1992 | Journal of medicinal chemistry, May-01, Volume: 35, Issue:9
| Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th |
| AID164935 | Compound was evaluated for the inhibitory activity against purine nucleoside phosphorylase (PNP) as a function of time of dialysis after 3 hours at 5 uM concentration | 1992 | Journal of medicinal chemistry, May-01, Volume: 35, Issue:9
| Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th |
| AID23441 | Partition coefficient in octanol/water system was determined at pH 7.4, as a measure of lipophilicity. | 1992 | Journal of medicinal chemistry, May-01, Volume: 35, Issue:9
| Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th |
| AID106500 | Compound was tested for the cytotoxic activity against MGL-8(B-cell) lymphoblasts | 1992 | Journal of medicinal chemistry, May-01, Volume: 35, Issue:9
| Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th |
| AID164933 | Compound was evaluated for the inhibitory activity against purine nucleoside phosphorylase (PNP) as a function of time of dialysis after 1 hours at 5 uM concentration | 1992 | Journal of medicinal chemistry, May-01, Volume: 35, Issue:9
| Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |