| Assay ID | Title | Year | Journal | Article |
|---|
| AID223849 | Compound was evaluated for the inhibitory activity against purine nucleoside phosphorylase (PNP) as a function of time of dialysis after 6 hours at 0.4 uM concentration | 1992 | Journal of medicinal chemistry, May-01, Volume: 35, Issue:9
| Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th |
| AID223847 | Compound was evaluated for the inhibitory activity against purine nucleoside phosphorylase (PNP) as a function of time of dialysis after 24 hours at 0.4 uM concentration | 1992 | Journal of medicinal chemistry, May-01, Volume: 35, Issue:9
| Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th |
| AID164920 | Ability to inhibit purine nucleoside phosphorylase (PNP) | 1992 | Journal of medicinal chemistry, May-01, Volume: 35, Issue:9
| Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th |
| AID229272 | Ratio of IC50 ino and Ki ino against purine nucleoside phosphorylase (PNP) | 1999 | Journal of medicinal chemistry, Jul-01, Volume: 42, Issue:13
| Structure-activity relationships for a class of inhibitors of purine nucleoside phosphorylase. |
| AID105110 | Cytotoxic effect on the growth of human T-and B-lymphoblastoid cell lines(MOLT-4 and MGL-8) evaluated by measuring inhibition of thymidine intake in presence of 10 uM deoxyguanosine | 1992 | Journal of medicinal chemistry, Apr-17, Volume: 35, Issue:8
| Inhibitors of human purine nucleoside phosphorylase. Synthesis and biological activities of 8-amino-3-benzylhypoxanthine and related analogues. |
| AID229634 | Selectivity ratio is evaluated as (IC50(50 mM PO4) / IC50(1 mM PO4) | 1993 | Journal of medicinal chemistry, Jan-08, Volume: 36, Issue:1
| Structure-based design of inhibitors of purine nucleoside phosphorylase. 1. 9-(arylmethyl) derivatives of 9-deazaguanine. |
| AID223848 | Compound was evaluated for the inhibitory activity against purine nucleoside phosphorylase (PNP) as a function of time of dialysis after 3 hours at 0.4 uM concentration | 1992 | Journal of medicinal chemistry, May-01, Volume: 35, Issue:9
| Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th |
| AID223845 | Compound was evaluated for the inhibitory activity against purine nucleoside phosphorylase (PNP) as a function of time of dialysis after 0 hours at 0.4 uM concentration | 1992 | Journal of medicinal chemistry, May-01, Volume: 35, Issue:9
| Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th |
| AID223846 | Compound was evaluated for the inhibitory activity against purine nucleoside phosphorylase (PNP) as a function of time of dialysis after 1 hours at 0.4 uM concentration | 1992 | Journal of medicinal chemistry, May-01, Volume: 35, Issue:9
| Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th |
| AID156068 | Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from calf spleen in 50 mM phosphate | 1993 | Journal of medicinal chemistry, Jan-08, Volume: 36, Issue:1
| Structure-based design of inhibitors of purine nucleoside phosphorylase. 1. 9-(arylmethyl) derivatives of 9-deazaguanine. |
| AID164913 | Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assay | 1992 | Journal of medicinal chemistry, Apr-17, Volume: 35, Issue:8
| Inhibitors of human purine nucleoside phosphorylase. Synthesis and biological activities of 8-amino-3-benzylhypoxanthine and related analogues. |
| AID164764 | Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM. | 1999 | Journal of medicinal chemistry, Jul-01, Volume: 42, Issue:13
| Structure-activity relationships for a class of inhibitors of purine nucleoside phosphorylase. |
| AID229806 | Ratio of Ki ino and Kimesg against purine nucleoside phosphorylase (PNP) | 1999 | Journal of medicinal chemistry, Jul-01, Volume: 42, Issue:13
| Structure-activity relationships for a class of inhibitors of purine nucleoside phosphorylase. |
| AID156067 | Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphate | 1993 | Journal of medicinal chemistry, Jan-08, Volume: 36, Issue:1
| Structure-based design of inhibitors of purine nucleoside phosphorylase. 1. 9-(arylmethyl) derivatives of 9-deazaguanine. |
| AID1571174 | Inhibition of human PNP | 2018 | MedChemComm, Dec-01, Volume: 9, Issue:12
| The transition to magic bullets - transition state analogue drug design. |
| AID164763 | Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using 2-amino-6-mercapto-7-methyl purine ribonucleoside (MESG) as substrate. | 1999 | Journal of medicinal chemistry, Jul-01, Volume: 42, Issue:13
| Structure-activity relationships for a class of inhibitors of purine nucleoside phosphorylase. |
| AID164756 | Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM. | 1999 | Journal of medicinal chemistry, Jul-01, Volume: 42, Issue:13
| Structure-activity relationships for a class of inhibitors of purine nucleoside phosphorylase. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |