Assay ID | Title | Year | Journal | Article |
AID164770 | Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP) | 1994 | Journal of medicinal chemistry, Jul-22, Volume: 37, Issue:15
| Structure-based design of inhibitors of purine nucleoside phosphorylase. 5. 9-Deazahypoxanthines. |
AID23441 | Partition coefficient in octanol/water system was determined at pH 7.4, as a measure of lipophilicity. | 1992 | Journal of medicinal chemistry, May-01, Volume: 35, Issue:9
| Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th |
AID156075 | PNP activity in human RBC | 1993 | Journal of medicinal chemistry, Apr-16, Volume: 36, Issue:8
| Nucleosides. 5. Synthesis of guanine and formycin B derivatives as potential inhibitors of purine nucleoside phosphorylase. |
AID1571174 | Inhibition of human PNP | 2018 | MedChemComm, Dec-01, Volume: 9, Issue:12
| The transition to magic bullets - transition state analogue drug design. |
AID23553 | Solubility in water | 1992 | Journal of medicinal chemistry, May-01, Volume: 35, Issue:9
| Inhibitors of human purine nucleoside phosphorylase. Synthesis of pyrrolo[3,2-d]pyrimidines, a new class of purine nucleoside phosphorylase inhibitors as potentially T-cell selective immunosuppressive agents. Description of 2,6-diamino-3,5-dihydro-7-(3-th |
AID164913 | Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assay | 1992 | Journal of medicinal chemistry, Apr-17, Volume: 35, Issue:8
| Inhibitors of human purine nucleoside phosphorylase. Synthesis and biological activities of 8-amino-3-benzylhypoxanthine and related analogues. |
AID230017 | Ratio of Ki values for guanine and related hypoxanthines in PNP inhibition assay | 1994 | Journal of medicinal chemistry, Jul-22, Volume: 37, Issue:15
| Structure-based design of inhibitors of purine nucleoside phosphorylase. 5. 9-Deazahypoxanthines. |
AID105110 | Cytotoxic effect on the growth of human T-and B-lymphoblastoid cell lines(MOLT-4 and MGL-8) evaluated by measuring inhibition of thymidine intake in presence of 10 uM deoxyguanosine | 1992 | Journal of medicinal chemistry, Apr-17, Volume: 35, Issue:8
| Inhibitors of human purine nucleoside phosphorylase. Synthesis and biological activities of 8-amino-3-benzylhypoxanthine and related analogues. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |