cetoleic acid profile

cetoleic acid: RN given refers to cpd with specified locant & without isomeric designation [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

cetoleic acid : A docosenoic acid having a cis-double bond at position 11. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

ID Source	ID
PubMed CID	5282771
CHEMBL ID	3103072
CHEBI ID	32428
SCHEMBL ID	198161
MeSH ID	M0064052

Synonym
cis-docos-11-enoic acid
docos-11c-enoic acid
cis-delta(11)-docosenoic acid
docos-11c-ensaeure
(z)-docos-11-enoic acid
cetoleic acid
cis-11-docosenoic acid
c22:1, n-11 cis
(z)-11-docosenoic acid
(11z)-docos-11-enoic acid
1002-96-6
CHEBI:32428 ,
cetoleinsaeure
22:1, n-11 cis
cis-cetoleic acid
LMFA01030088
11z-docosenoic acid
unii-62ezi2c5se
11-docosenoic acid, (z)-
62ezi2c5se ,
SCHEMBL198161
CHEMBL3103072
cetolic acid
22:1(n-11)
j12.483d ,
(11z)-11-docosenoic acid
11-docosenoic acid, cis-
KJDZDTDNIULJBE-QXMHVHEDSA-N
cis-cetoleate
11z-docosenoate
cis-cetoleic acid (cis-22:1n-11)
DTXSID00920491
Q27114930
11-docosenoic acid, (11z)-
PD150669
fatty acid cis 22:1 n-11
c22:1.n-11 cis
fatty acid 22:1 n-11 cis

Excerpt	Reference	Relevance
"Cetoleic acid (22:1n-11) is a good indicator of diet in marine predators and has proven to be an important fatty acid (FA) when using adipose tissue FA composition to study diet in marine mammals and seabirds. "	( Metabolism of dietary cetoleic acid (22:1n-11) in mink (Mustela vison) and gray seals (Halichoerus grypus) studied using radiolabeled fatty acids. Cooper, MH; Iverson, SJ; Rouvinen-Watt, K, )	1.89

Role	Description
Daphnia tenebrosa metabolite	A Daphnia metabolite produced by the species Daphnia tenebrosa.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Class	Description
docosenoic acid	A C22, monounsaturated fatty acid carrying a C=C double bond at any position.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Assay ID	Title	Year	Journal	Article
AID1063391	Induction of dendrite extension in rat cortical neurons assessed as inhibition of amyloid beta (25 to 35)-induced neuronal degeneration at 1 uM after 4 days by fluorescence microscopic analysis	2014	Bioorganic & medicinal chemistry letters, Jan-15, Volume: 24, Issue:2	Synthesis of long-chain fatty acid derivatives as a novel anti-Alzheimer's agent.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	3 (42.86)	18.7374
1990's	1 (14.29)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (42.86)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	1 (12.50%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	7 (87.50%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
beta-alanine [no description available]	4.41	1	1	amino acid zwitterion; beta-amino acid	agonist; fundamental metabolite; human metabolite; inhibitor; neurotransmitter
2-aminoadipic acid 2-Aminoadipic Acid: A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).. 2-aminoadipic acid : An alpha-amino acid that is adipic acid bearing a single amino substituent at position 2. An intermediate in the formation of lysine.	9.41	1	1	amino dicarboxylic acid; dicarboxylic fatty acid; non-proteinogenic alpha-amino acid	Caenorhabditis elegans metabolite; mammalian metabolite
hydroxyproline Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.. hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.	9.41	1	1	4-hydroxyproline; L-alpha-amino acid zwitterion	human metabolite; mouse metabolite; plant metabolite
behenic acid behenic acid: RN given refers to parent cpd; structure. docosanoic acid : A straight-chain, C22, long-chain saturated fatty acid.	2.1	1	0	long-chain fatty acid; straight-chain saturated fatty acid	plant metabolite
octacosanoic acid octacosanoic acid: RN given refers to parent. octacosanoic acid : A straight-chain saturated fatty acid that is octacosane in which one of the terminal methyl groups has been oxidised to the corresponding carboxy group.	2.1	1	0	straight-chain saturated fatty acid; ultra-long-chain fatty acid	plant metabolite
eicosapentaenoic acid icosapentaenoic acid : Any straight-chain, C20 polyunsaturated fatty acid having five C=C double bonds.. all-cis-5,8,11,14,17-icosapentaenoic acid : An icosapentaenoic acid having five cis-double bonds at positions 5, 8, 11, 14 and 17.	2.42	2	0	icosapentaenoic acid; omega-3 fatty acid	anticholesteremic drug; antidepressant; antineoplastic agent; Daphnia galeata metabolite; fungal metabolite; micronutrient; mouse metabolite; nutraceutical
palmitoyl coenzyme a Palmitoyl Coenzyme A: A fatty acid coenzyme derivative which plays a key role in fatty acid oxidation and biosynthesis.. palmitoyl-CoA : A long-chain fatty acyl-CoA resulting from the formal condensation of the carboxy group of hexadecanoic acid with the thiol group of coenzyme A.	1.95	1	0	11,12-saturated fatty acyl-CoA; 3-substituted propionyl-CoA; long-chain fatty acyl-CoA; palmitoyl bioconjugate	Escherichia coli metabolite; mouse metabolite
docosapentaenoic acid docosapentaenoic acid : Any straight-chain, C22 fatty acid having five C=C double bonds.. (7Z,10Z,13Z,16Z,19Z)-docosapentaenoic acid : The all-cis-isomer of a C22 polyunsaturated fatty acid having five double bonds in the 7-, 10-, 13-, 16- and 19-positions.	2.21	1	0	docosapentaenoic acid; omega-3 fatty acid	algal metabolite; human metabolite

Condition	Relationship Strength	Studies	Trials
Acute Confusional Senile Dementia [description not available]	2.1	1	0
Alzheimer Disease A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)	2.1	1	0
Overweight A status with BODY WEIGHT that is above certain standards. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal over fat.	9.41	1	1
Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	1.96	1	0
Lipidoses Conditions characterized by abnormal lipid deposition due to disturbance in lipid metabolism, such as hereditary diseases involving lysosomal enzymes required for lipid breakdown. They are classified either by the enzyme defect or by the type of lipid involved.	1.96	1	0
Cardiomyopathies, Primary [description not available]	1.96	1	0
Carditis [description not available]	1.96	1	0
Cardiomyopathies A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS).	1.96	1	0
Myocarditis Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies.	1.96	1	0

cetoleic acid

Description

Cross-References

Synonyms (38)

Research Excerpts

Overview

Roles (1)

Drug Classes (1)

Bioassays (1)

Research

Studies (7)

Market Indicators

Research Demand Index: 30.23

Study Types