armillaridin: isolated from Armillaria mellea mycelium I; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 51351607 |
| CHEMBL ID | 1762764 |
| CHEBI ID | 185923 |
| MeSH ID | M0128079 |
| Synonym |
|---|
| armillaridin |
| [(2r,2as,4as,7as,7br)-3-ormyl-2a-hydroxy-6,6,7b-trimethyl-1,2,4a,5,7,7a-hexahydrocyclobuta[e]inden-2-yl] 3-chloro-6-hydroxy-4-methoxy-2-methylbenzoate |
| CHEBI:185923 |
| CHEMBL1762764 |
| Class | Description |
|---|---|
| sesquiterpenoid | Any terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups). |
| benzoate ester | Esters of benzoic acid or substituted benzoic acids. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID589479 | Cytotoxicity against human Jurkat cells | 2011 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7 | In vitro cytotoxicity of melleolide antibiotics: structural and mechanistic aspects. |
| AID589480 | Cytotoxicity against human HeLa cells | 2011 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7 | In vitro cytotoxicity of melleolide antibiotics: structural and mechanistic aspects. |
| AID1183884 | Cytotoxicity against human MONO-MAC-6 cells after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Aug-01, Volume: 22, Issue:15 | Melleolides induce rapid cell death in human primary monocytes and cancer cells. |
| AID589481 | Cytotoxicity against human K562 cells | 2011 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7 | In vitro cytotoxicity of melleolide antibiotics: structural and mechanistic aspects. |
| AID1183883 | Cytotoxicity against human THP1 cells after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Aug-01, Volume: 22, Issue:15 | Melleolides induce rapid cell death in human primary monocytes and cancer cells. |
| AID1183885 | Cytotoxicity against human primary monocytes after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Aug-01, Volume: 22, Issue:15 | Melleolides induce rapid cell death in human primary monocytes and cancer cells. |
| AID589478 | Cytotoxicity against human MCF7 cells | 2011 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7 | In vitro cytotoxicity of melleolide antibiotics: structural and mechanistic aspects. |
| AID1183886 | Cytotoxicity against human K562 cells after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Aug-01, Volume: 22, Issue:15 | Melleolides induce rapid cell death in human primary monocytes and cancer cells. |
| AID1183887 | Cytotoxicity against human HeLa cells after 24 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry, Aug-01, Volume: 22, Issue:15 | Melleolides induce rapid cell death in human primary monocytes and cancer cells. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Substance | Description | Relationhip Strength | Studies | Trials | Classes | Roles |
|---|---|---|---|---|---|---|
| cycloheximide | [no description available] | medium | 2 | 0 | antibiotic fungicide; cyclic ketone; dicarboximide; piperidine antibiotic; piperidones; secondary alcohol | anticoronaviral agent; bacterial metabolite; ferroptosis inhibitor; neuroprotective agent; protein synthesis inhibitor |
| dactinomycin | [no description available] | medium | 2 | 0 | actinomycin | mutagen |
| carbonyl cyanide m-chlorophenyl hydrazone | [no description available] | medium | 1 | 0 | hydrazone; monochlorobenzenes; nitrile | antibacterial agent; geroprotector; ionophore |
| staurosporine | [no description available] | medium | 1 | 0 | indolocarbazole alkaloid; organic heterooctacyclic compound | apoptosis inducer; bacterial metabolite; EC 2.7.11.13 (protein kinase C) inhibitor; geroprotector |
| pretubulysin | [no description available] | medium | 1 | 0 | ||
| adenine | [no description available] | medium | 1 | 0 | 6-aminopurines; purine nucleobase | Daphnia magna metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite |
| 3-methyladenine | [no description available] | medium | 1 | 0 | ||
| sesquiterpenes | [no description available] | medium | 5 | 0 | ||
| diacetyldichlorofluorescein | [no description available] | medium | 1 | 0 | ||
| erythrosine | [no description available] | medium | 1 | 0 | ||
| chamazulene | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| mansonone c | [no description available] | low | 0 | 0 | 1,2-naphthoquinones; sesquiterpenoid | |
| artemether | [no description available] | low | 0 | 0 | artemisinin derivative; cyclic acetal; organic peroxide; semisynthetic derivative; sesquiterpenoid | antimalarial |
| elemol | [no description available] | low | 0 | 0 | olefinic compound; sesquiterpenoid; tertiary alcohol | fragrance; plant metabolite |
| spathulenol | [no description available] | low | 0 | 0 | carbotricyclic compound; olefinic compound; sesquiterpenoid; tertiary alcohol | anaesthetic; plant metabolite; vasodilator agent; volatile oil component |
| xanthorrhizol | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| phomenone | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| judaicin (eudesmane naphthofuran) | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| hernandulcin | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| ar-turmerone | [no description available] | low | 0 | 0 | enone; sesquiterpenoid | EC 3.1.1.7 (acetylcholinesterase) inhibitor; plant metabolite |
| frullanolide | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| albicanol | [no description available] | low | 0 | 0 | carbobicyclic compound; homoallylic alcohol; primary alcohol; sesquiterpenoid | antifeedant; antifungal agent; antineoplastic agent; fungal metabolite; mammalian metabolite; marine metabolite; plant metabolite |
| valeranone | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| aromadendrene | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| procurcumenol | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| fumagillol | [no description available] | low | 0 | 0 | secondary alcohol; sesquiterpenoid; spiro-epoxide | antimicrobial agent |
| illudin m | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| illudin s | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| o-(chloroacetylcarbamoyl)fumagillol | [no description available] | low | 0 | 0 | carbamate ester; organochlorine compound; semisynthetic derivative; sesquiterpenoid; spiro-epoxide | angiogenesis inhibitor; antineoplastic agent; EC 1.5.1.3 (dihydrofolate reductase) inhibitor; methionine aminopeptidase 2 inhibitor; retinoic acid receptor alpha antagonist |
| bakkenolide a | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| bisabolol | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| solavetivone | [no description available] | low | 0 | 0 | cyclic ketone; sesquiterpenoid; spiro compound | phytoalexin; plant metabolite |
| macrocarpal b | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| bucladesine | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| elatol | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| 7-hydroxycadalin | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| 2-[(4,4-dimethyl-2,6-dioxocyclohexyl)-(3-pyridinyl)methyl]-5,5-dimethylcyclohexane-1,3-dione | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| 2-hydroxy-2,2-bis(4-methylphenyl)-N'-(2-pyridinyl)acetohydrazide | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| nootkatone | [no description available] | low | 0 | 0 | carbobicyclic compound; enone; sesquiterpenoid | fragrance; insect repellent; plant metabolite |
| drimenol | [no description available] | low | 0 | 0 | homoallylic alcohol; octahydronaphthalenes; primary alcohol; sesquiterpenoid | |
| atractylon | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| zoapatanol | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| budlein a | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| petasin | [no description available] | low | 0 | 0 | alicyclic ketone; enoate ester; enone; sesquiterpenoid | anti-allergic agent; EC 2.7.11.31 {[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase} activator; plant metabolite; vasodilator agent |
| astrogorgiadiol | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| anhydrovitamin a | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| rotundone | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| 4-nerolidylcatechol | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| alpha-isomethylionone | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| grifolin | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| s-trans,trans-farnesylthiosalicylic acid | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| zerumbone | [no description available] | low | 0 | 0 | cyclic ketone; sesquiterpenoid | anti-inflammatory agent; glioma-associated oncogene inhibitor; plant metabolite |
| aurachin d | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| deoxyelephantopin | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| ascofuranone | [no description available] | low | 0 | 0 | dihydroxybenzaldehyde; meroterpenoid; monochlorobenzenes; olefinic compound; resorcinols; sesquiterpenoid; tetrahydrofuranone | angiogenesis inhibitor; antilipemic drug; antineoplastic agent; antiprotozoal drug; fungal metabolite |
| fusarin c | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| n-acetyl-s-farnesylcysteine | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| tautomycetin | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| valerenic acid | [no description available] | low | 0 | 0 | carbobicyclic compound; monocarboxylic acid; sesquiterpenoid | GABA modulator; plant metabolite; sedative; volatile oil component |
| artesunate | [no description available] | low | 0 | 0 | artemisinin derivative; cyclic acetal; dicarboxylic acid monoester; hemisuccinate; semisynthetic derivative; sesquiterpenoid | antimalarial; antineoplastic agent; ferroptosis inducer |
| dihydroartemisinin | [no description available] | low | 0 | 0 | sesquiterpenoid | antimalarial |
| xenovulene a | [no description available] | low | 0 | 0 | cyclic ether; enone; organic heterotetracyclic compound; sesquiterpenoid | GABA antagonist; metabolite |
| LSM-1328 | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| jaeschkeanadiol | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| hypnophilin | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| artemisic acid | [no description available] | low | 0 | 0 | carbobicyclic compound; monocarboxylic acid; octahydronaphthalenes; sesquiterpenoid | metabolite |
| dihydroartemisinic acid | [no description available] | low | 0 | 0 | carbobicyclic compound; monocarboxylic acid; octahydronaphthalenes; sesquiterpenoid | plant metabolite |
| ascochlorin | [no description available] | low | 0 | 0 | cyclohexanones; dihydroxybenzaldehyde; meroterpenoid; monochlorobenzenes; olefinic compound; resorcinols; sesquiterpenoid | angiogenesis inhibitor; antifungal agent; antineoplastic agent; antiprotozoal drug; fungal metabolite |
| cubebol | [no description available] | low | 0 | 0 | carbotricyclic compound; sesquiterpenoid; tertiary alcohol | |
| 5-methyl-2-(3-oxo-1,2,2-trimethylcyclopentyl)benzoquinone | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| laurinterol | [no description available] | low | 0 | 0 | organobromine compound; phenols; sesquiterpenoid | antibacterial agent; apoptosis inducer; EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor; metabolite |
| pyripyropene a | [no description available] | low | 0 | 0 | organic heterotetracyclic compound; sesquiterpenoid | acyl-CoA:cholesterol acyltransferase 2 inhibitor; metabolite |
| viridiflorol | [no description available] | low | 0 | 0 | carbotricyclic compound; sesquiterpenoid; tertiary alcohol | anti-inflammatory agent; antifeedant; antimycobacterial drug; plant metabolite; volatile oil component |
| cyperotundone | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| oplodiol | [no description available] | low | 0 | 0 | carbobicyclic compound; octahydronaphthalenes; secondary alcohol; sesquiterpenoid; tertiary alcohol | plant metabolite |
| curcumol | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| isotrichodermin | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| saliniketal a | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| saliniketal b | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| Pechueloic acid | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| atheronal-a | [no description available] | low | 0 | 0 | sesquiterpenoid | |
| albaflavenone | [no description available] | low | 0 | 0 | carbocyclic antibiotic; carbotricyclic compound; cyclic terpene ketone; enone; sesquiterpenoid | bacterial metabolite |
| (+)-(7S)-sydonic acid | [no description available] | low | 0 | 0 | aromatic alcohol; monohydroxybenzoic acid; sesquiterpenoid | Aspergillus metabolite |
| digallic acid | [no description available] | low | 0 | 0 | benzoate ester; gallate ester | |
| mdl 72222 | [no description available] | low | 0 | 0 | benzoate ester | |
| benfluorex | [no description available] | low | 0 | 0 | benzoate ester | |
| benzocaine | [no description available] | low | 0 | 0 | benzoate ester; substituted aniline | allergen; antipruritic drug; sensitiser; topical anaesthetic |
| benzyl benzoate | [no description available] | low | 0 | 0 | benzoate ester; benzyl ester | acaricide; plant metabolite; scabicide |
| butacaine | [no description available] | low | 0 | 0 | benzoate ester | |
| butamben | [no description available] | low | 0 | 0 | amino acid ester; benzoate ester; primary amino compound; substituted aniline | local anaesthetic |
| camostat | [no description available] | low | 0 | 0 | benzoate ester; carboxylic ester; diester; guanidines; tertiary carboxamide | anti-inflammatory agent; anticoronaviral agent; antifibrinolytic drug; antihypertensive agent; antineoplastic agent; antiviral agent; serine protease inhibitor |
| dilazep | [no description available] | low | 0 | 0 | benzoate ester; diazepane; diester; methoxybenzenes | cardioprotective agent; platelet aggregation inhibitor; vasodilator agent |
| ethyl piperidinoacetylaminobenzoate | [no description available] | low | 0 | 0 | benzoate ester; piperidines | |
| gabexate | [no description available] | low | 0 | 0 | benzoate ester | |
| benzoic acid [2-methyl-2-(propylamino)propyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| methyl salicylate | [no description available] | low | 0 | 0 | benzoate ester; methyl ester; salicylates | flavouring agent; insect attractant; metabolite |
| benoxinate | [no description available] | low | 0 | 0 | amino acid ester; benzoate ester; substituted aniline; tertiary amino compound | drug allergen; local anaesthetic; topical anaesthetic |
| Phenyliodoundecynoate | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| procaine | [no description available] | low | 0 | 0 | benzoate ester; substituted aniline; tertiary amino compound | central nervous system depressant; drug allergen; local anaesthetic; peripheral nervous system drug |
| proxymetacaine | [no description available] | low | 0 | 0 | benzoate ester | |
| salicylsalicylic acid | [no description available] | low | 0 | 0 | benzoate ester; benzoic acids; phenols; salicylates | antineoplastic agent; antirheumatic drug; EC 3.5.2.6 (beta-lactamase) inhibitor; hypoglycemic agent; non-narcotic analgesic; non-steroidal anti-inflammatory drug; prodrug |
| tetracaine | [no description available] | low | 0 | 0 | benzoate ester; tertiary amino compound | local anaesthetic |
| butyl phthalyl butyl glycolate | [no description available] | low | 0 | 0 | benzoate ester | |
| methyl n-methylanthranilate | [no description available] | low | 0 | 0 | benzoate ester; methyl ester; secondary amino compound; substituted aniline | animal metabolite; fungal metabolite; plant metabolite |
| propoxycaine | [no description available] | low | 0 | 0 | benzoate ester | |
| isoamyl salicylate | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| Ethyl 2-aminobenzoate | [no description available] | low | 0 | 0 | benzoate ester | |
| acetyleugenol | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| methyl benzoate | [no description available] | low | 0 | 0 | benzoate ester; methyl ester | insect attractant; metabolite |
| ethyl benzoate | [no description available] | low | 0 | 0 | benzoate ester; ethyl ester | flavouring agent; fragrance; volatile oil component |
| diphenylcarboxylate | [no description available] | low | 0 | 0 | benzoate ester | |
| propylparaben | [no description available] | low | 0 | 0 | benzoate ester; paraben; phenols | antifungal agent; antimicrobial agent |
| dimethocaine | [no description available] | low | 0 | 0 | benzoate ester | |
| benzylparaben | [no description available] | low | 0 | 0 | benzoate ester; benzyl ester | |
| parethoxycaine | [no description available] | low | 0 | 0 | benzoate ester | |
| benzonatate | [no description available] | low | 0 | 0 | benzoate ester; secondary amino compound; substituted aniline | anaesthetic; antitussive |
| oxyphenisatin acetate | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| phenyl salicylate | [no description available] | low | 0 | 0 | benzoate ester; phenols; salicylates | ultraviolet filter |
| homosalate | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| benzyl salicylate | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| 2-ethylhexyl salicylate | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| methyl 4-anisate | [no description available] | low | 0 | 0 | benzoate ester; monomethoxybenzene | |
| deserpidine | [no description available] | low | 0 | 0 | alkaloid ester; benzoate ester; methyl ester; organic heteropentacyclic compound; yohimban alkaloid | |
| chloroprocaine | [no description available] | low | 0 | 0 | benzoate ester; monochlorobenzenes | central nervous system depressant; local anaesthetic; peripheral nervous system drug |
| 2-Phenylethyl 2-aminobenzoate | [no description available] | low | 0 | 0 | benzoate ester | |
| methyl anthranilate | [no description available] | low | 0 | 0 | benzoate ester | flavouring agent; metabolite |
| resorcinol monobenzoate | [no description available] | low | 0 | 0 | benzoate ester | allergen |
| tetrracaine hydrochloride | [no description available] | low | 0 | 0 | benzoate ester | |
| p-cresyl acetate | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| amylocaine | [no description available] | low | 0 | 0 | benzoate ester | |
| hexylcaine | [no description available] | low | 0 | 0 | benzoate ester | |
| piperocaine | [no description available] | low | 0 | 0 | benzoate ester | |
| cyclomethycaine | [no description available] | low | 0 | 0 | benzoate ester | |
| benzoylcholine | [no description available] | low | 0 | 0 | benzoate ester | |
| propyl benzoate | [no description available] | low | 0 | 0 | benzoate ester | antimicrobial food preservative; flavouring agent; plant metabolite |
| tri-(2-ethylhexyl)trimellitate | [no description available] | low | 0 | 0 | benzoate ester | |
| cue-lure | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| metabutoxycaine | [no description available] | low | 0 | 0 | benzoate ester | |
| methyl vanillate | [no description available] | low | 0 | 0 | aromatic ether; benzoate ester; phenols | antioxidant; plant metabolite |
| hexyl salicylate | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-Propenyl 2-aminobenzoate | [no description available] | low | 0 | 0 | benzoate ester | |
| ethyl 4-dimethylaminobenzoate | [no description available] | low | 0 | 0 | benzoate ester; ethyl ester; tertiary amino compound | |
| padimate-o | [no description available] | low | 0 | 0 | benzoate ester | |
| etofenamate | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-aminosulfonyl-benzoic acid methyl ester | [no description available] | low | 0 | 0 | benzoate ester; methyl ester; sulfonamide | marine xenobiotic metabolite |
| bopindolol | [no description available] | low | 0 | 0 | aromatic ether; benzoate ester; methylindole; secondary amino compound | |
| sulfometuron methyl | [no description available] | low | 0 | 0 | benzoate ester; N-sulfonylurea; pyrimidines | EC 2.2.1.6 (acetolactate synthase) inhibitor; herbicide |
| metsulfuron methyl | [no description available] | low | 0 | 0 | 1,3,5-triazines; benzoate ester; N-sulfonylurea | environmental contaminant; herbicide; xenobiotic |
| baccatin iii | [no description available] | low | 0 | 0 | acetate ester; benzoate ester; tetracyclic diterpenoid | plant metabolite |
| cresatin | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| ibopamine | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| methyl syringate | [no description available] | low | 0 | 0 | benzoate ester; dimethoxybenzene; phenols | plant metabolite |
| methyl gentisate | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| benzoylmetronidazole | [no description available] | low | 0 | 0 | benzoate ester | antibacterial drug; antimicrobial agent; antiparasitic agent; antitrichomonal drug; prodrug |
| isoamyl 4-n,n-dimethylaminobenzoate | [no description available] | low | 0 | 0 | benzoate ester | |
| methyl 2-(((((4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl)amino)carbonyl)amino)sulfonyl)benzoate | [no description available] | low | 0 | 0 | aromatic ether; benzoate ester; diamino-1,3,5-triazine; methyl ester; N-sulfonylurea | EC 2.2.1.6 (acetolactate synthase) inhibitor; herbicide |
| triflusulfuron-methyl | [no description available] | low | 0 | 0 | 1,3,5-triazines; aromatic ether; benzoate ester; methyl ester; N-sulfonylurea; organofluorine compound; tertiary amino compound | agrochemical; EC 2.2.1.6 (acetolactate synthase) inhibitor; proherbicide |
| lecanoric acid | [no description available] | low | 0 | 0 | benzoate ester | |
| Meprylcaine hydrochloride | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-acetamidophenyl-2-thiophenecarboxylate | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| 8-hydroxynorcocaine | [no description available] | low | 0 | 0 | benzoate ester | |
| succinobucol | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| estradiol 3-benzoate | [no description available] | low | 0 | 0 | 17beta-hydroxy steroid; benzoate ester | estrogen receptor agonist; xenoestrogen |
| cochlearine | [no description available] | low | 0 | 0 | benzoate ester | |
| 3-(2-Methylpropanoyloxy)-8-(2-methylbutanoyloxy)-9,10-epoxy-p-mentha-1,3,5-triene | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| agnuside | [no description available] | low | 0 | 0 | benzoate ester; beta-D-glucoside; cyclopentapyran; iridoid monoterpenoid; monosaccharide derivative; phenols; terpene glycoside | anti-inflammatory agent; cyclooxygenase 2 inhibitor; plant metabolite; pro-angiogenic agent |
| cocaine | [no description available] | low | 0 | 0 | benzoate ester; methyl ester; tertiary amino compound; tropane alkaloid | adrenergic uptake inhibitor; central nervous system stimulant; dopamine uptake inhibitor; environmental contaminant; local anaesthetic; mouse metabolite; plant metabolite; serotonin uptake inhibitor; sodium channel blocker; sympathomimetic agent; vasoconstrictor agent; xenobiotic |
| benzoylecgonine | [no description available] | low | 0 | 0 | benzoate ester; tropane alkaloid | epitope; human xenobiotic metabolite; marine xenobiotic metabolite; plant metabolite |
| 4-[2-(4-methoxycarbonylphenyl)iminohydrazinyl]benzoic acid methyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| cocaethylene | [no description available] | low | 0 | 0 | benzoate ester | |
| norcocaine | [no description available] | low | 0 | 0 | benzoate ester | |
| 2,4-dichlorobenzoic acid 1,2,4-triazol-1-ylmethyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-[[[[8-[(1-tert-butyl-5-tetrazolyl)methyl]-8-azabicyclo[3.2.1]octan-3-yl]amino]-oxomethyl]amino]benzoic acid ethyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| benzoic acid [5-amino-1-(4-methoxyphenyl)sulfonyl-3-pyrazolyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| Methyl 2-[(methylsulfonyl)amino]benzoate | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-[[[2-(4-fluorophenyl)ethylamino]-sulfanylidenemethyl]amino]benzoic acid ethyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| acetic acid [4-[oxo-(2-phenylethylamino)methyl]phenyl] ester | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| 4-[[[2-(3-methylphenyl)ethylamino]-sulfanylidenemethyl]amino]benzoic acid methyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| acetic acid [2-(4-acetamido-6-phenyl-1,3,5-triazin-2-yl)phenyl] ester | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| benzoic acid (2-oxo-2-thiophen-2-ylethyl) ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-[5-[oxo-(3-pyridinylamino)methyl]-2-furanyl]benzoic acid ethyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-[[(cyclohexylamino)-oxomethyl]amino]benzoic acid methyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-[[(4-hydroxy-1-piperidinyl)-sulfanylidenemethyl]amino]benzoic acid ethyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-[[(1,3-benzodioxol-5-ylamino)-oxomethyl]amino]benzoic acid methyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-[[[(5-chloro-2-pyridinyl)amino]-oxomethyl]amino]benzoic acid methyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-[[(4-methoxyanilino)-oxomethyl]amino]benzoic acid methyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-[[[(2-methoxyphenyl)methylamino]-oxomethyl]amino]benzoic acid ethyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-[[1-azepanyl(oxo)methyl]amino]benzoic acid ethyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-[[(4-methyl-1-pyrazolyl)-oxomethyl]amino]benzoic acid methyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-[5-(2-phenylethyl)-2-sulfanylidene-1,3,5-triazinan-1-yl]benzoic acid ethyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-(4-methoxycarbonylphenyl)-1,2,6-trimethyl-4H-pyridine-3,5-dicarboxylic acid dimethyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 3-[[oxo-[3-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]methoxy]methyl]benzoic acid ethyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-[[diethylamino(oxo)methyl]amino]benzoic acid ethyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-(5-formyl-2-furanyl)benzoic acid propyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-[[(3,4-dimethoxyanilino)-oxomethyl]amino]benzoic acid butyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-(dimethylamino)benzoic acid (3,5-dimethyl-4-isoxazolyl)methyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-[4-(difluoromethylthio)anilino]benzoic acid [2-(cyclopropylamino)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-hydroxybenzoic acid [2-[[(1-methyl-2-pyrrolyl)-oxomethyl]amino]-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| 4-[(2-methoxyphenyl)-methylsulfamoyl]benzoic acid [2-[(5-methyl-3-isoxazolyl)amino]-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 3-[(2-methoxyphenyl)-prop-2-enylsulfamoyl]benzoic acid [2-(1H-indol-3-yl)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-chloro-3-(1-piperidinylsulfonyl)benzoic acid [2-(4-amino-1,3-dimethyl-2,6-dioxo-5-pyrimidinyl)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-[2-nitro-4-(trifluoromethyl)phenyl]sulfinylacetic acid (4-chlorophenyl) ester | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| 4-[[[(2-methoxy-1-oxoethyl)hydrazo]-sulfanylidenemethyl]amino]benzoic acid ethyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| acetic acid [4-[(1-oxo-2-phenylethyl)amino]phenyl] ester | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| 3-(dimethylamino)propyl benzoate | [no description available] | low | 0 | 0 | benzoate ester | |
| 2,4-difluorobenzoic acid [2-(cyclopropylamino)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| benzoic acid [2-(2-furanylmethylamino)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-(diethylsulfamoyl)benzoic acid [2-[4-(6-methyl-1,3-benzothiazol-2-yl)anilino]-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-methylbenzoic acid [2-(1H-indol-3-yl)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-ethoxy-3-pyridinecarboxylic acid (4-methoxycarbonylphenyl)methyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-(dimethylamino)benzoic acid [2-(cycloheptylamino)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-(thiophen-2-ylsulfonylamino)benzoic acid [2-(cyclohexylamino)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-(2-furanylmethylamino)benzoic acid [2-oxo-2-(3-oxo-2,4-dihydroquinoxalin-1-yl)ethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-hydroxy-4-methylbenzoic acid [2-(2-chloroanilino)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| 4-(dimethylsulfamoyl)benzoic acid [2-(2-furanylmethylamino)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-[[2-[(2-hydroxyphenyl)-oxomethoxy]-1-oxoethyl]amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid methyl ester | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| 4-chloro-3-(1-pyrrolidinylsulfonyl)benzoic acid [2-(butylamino)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 3-hydroxybenzoic acid [2-(1H-indol-3-yl)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| 3,4-diethoxybenzoic acid [2-[(5-methyl-3-isoxazolyl)amino]-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 3-[(3,4-difluorophenyl)sulfonylamino]benzoic acid [2-[[(2-methylpropylamino)-oxomethyl]amino]-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-(butylamino)benzoic acid [2-oxo-2-(4-sulfamoylanilino)ethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 3-(diethylsulfamoyl)benzoic acid [2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-(diethylsulfamoyl)benzoic acid 1,3-benzodioxol-5-yl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 3-(methanesulfonamido)benzoic acid methyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| ethyl 3-amino-4-(methylamino)benzoate | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-[[3-(methylthio)-1,2,4-thiadiazol-5-yl]thio]acetic acid (4-acetamidophenyl) ester | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| 3-amino-4-chlorobenzoic acid [2-oxo-2-(1-pyrrolidinyl)ethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonylamino)benzoic acid thiophen-2-ylmethyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-amino-4-chlorobenzoic acid [2-oxo-2-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)ethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 2,6-difluorobenzoic acid 2,3-dihydro-1,4-benzodioxin-3-ylmethyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 3-[(4-methylphenyl)sulfamoyl]benzoic acid [2-(2-furanylmethylamino)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| bentiamine | [no description available] | low | 0 | 0 | benzoate ester | |
| 3-[5-[bis(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-2-furanyl]benzoic acid methyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-[2-(cyclohexylamino)-2-oxo-1-[(1-oxo-2-thiophen-2-ylethyl)-(phenylmethyl)amino]ethyl]benzoic acid methyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-[[(2,3-dihydro-1H-inden-1-ylamino)-sulfanylidenemethyl]amino]benzoic acid methyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 3,4-dimethylbenzoic acid (6-methyl-3-pyridinyl) ester | [no description available] | low | 0 | 0 | benzoate ester | |
| benzoic acid [4-(6-amino-5-cyano-3-methyl-2,4-dihydropyrano[2,3-c]pyrazol-4-yl)-2-methoxyphenyl] ester | [no description available] | low | 0 | 0 | benzoate ester; pyranopyrazole | |
| 4-chlorobenzoic acid (5-methyl-2-pyridin-4-yl-4-thiazolyl) ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-[3-methyl-5-(4-methylphenyl)-6-oxo-2,4-dihydropyrrolo[3,4-c]pyrazol-4-yl]benzoic acid methyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 5-(diethylsulfamoyl)-2-hydroxybenzoic acid [2-oxo-2-[4-(trifluoromethoxy)anilino]ethyl] ester | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| 4-[[[2-(4-methoxyphenyl)-3-thiazolidinyl]-sulfanylidenemethyl]amino]benzoic acid ethyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-(carbamoylamino)benzoic acid [2-(3-chloro-4-methylanilino)-2-oxo-1-phenylethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-hydroxybenzoic acid [2-(2-ethoxyanilino)-2-oxo-1-phenylethyl] ester | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| 2-(2-furanylmethylamino)benzoic acid [2-[(3-cyano-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)amino]-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| acetic acid [2-[2-acetyl-3-(4-methoxyphenyl)-3,4-dihydropyrazol-5-yl]phenyl] ester | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| 3-pyridinecarboxylic acid [4-[heptoxy(oxo)methyl]phenyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-hydroxy-5-[(4-methoxyphenyl)sulfamoyl]benzoic acid [2-[1-(3-bicyclo[2.2.1]heptanyl)ethylamino]-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| 3,5-dimethyl-4-oxo-6-thieno[2,3-d]pyrimidinecarboxylic acid (4-methylphenyl) ester | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| 4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonylamino)benzoic acid [2-(cyclopropylamino)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-[4-(difluoromethylthio)anilino]benzoic acid [2-(dimethylamino)-2-oxoethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-ethylbenzoic acid [2-(2-ethoxyanilino)-2-oxo-1-phenylethyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-[[[[2-(3-pyridinyl)-1-piperidinyl]amino]-sulfanylidenemethyl]amino]benzoic acid methyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| cinnamyl anthranilate | [no description available] | low | 0 | 0 | benzoate ester | |
| gabexate methanesulfonate | [no description available] | low | 0 | 0 | benzoate ester; guanidines; methanesulfonate salt | |
| yunaconitine | [no description available] | low | 0 | 0 | acetate ester; aromatic ether; benzoate ester; bridged compound; diterpene alkaloid; organic heteropolycyclic compound; polyether; secondary alcohol; tertiary alcohol; tertiary amino compound | antifeedant; human urinary metabolite; phytotoxin; plant metabolite; xenobiotic |
| paeonilide | [no description available] | low | 0 | 0 | benzoate ester | metabolite |
| 10-isobutyryloxy-8,9-epoxythymol isobutyrate | [no description available] | low | 0 | 0 | benzoate ester; phenols | |
| butafenacil | [no description available] | low | 0 | 0 | benzoate ester; diester; monochlorobenzenes; olefinic compound; organofluorine compound | EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor; herbicide |
| 4-[3-(2-furanyl)-4-(3-nitrophenyl)-6-oxo-2,4-dihydropyrrolo[3,4-c]pyrazol-5-yl]benzoic acid ethyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-[[(4-methyl-1-piperidinyl)-sulfanylidenemethyl]amino]benzoic acid ethyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-methylbenzoic acid [6-[[[5-[[cyclopropyl(oxo)methyl]amino]-1,3,4-thiadiazol-2-yl]thio]methyl]-4-oxo-3-pyranyl] ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-[[4-cyclohexyl-3-(2-hydroxyethyl)-1-piperazinyl]methyl]benzoic acid methyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 4-[[[2-(1-azepanyl)ethyl-(2-furanylmethyl)amino]-sulfanylidenemethyl]amino]benzoic acid ethyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| 2-[[[(1-ethyl-3,5-dimethyl-4-pyrazolyl)methylamino]-oxomethyl]amino]benzoic acid methyl ester | [no description available] | low | 0 | 0 | benzoate ester | |
| avilamycin a | [no description available] | low | 0 | 0 | benzoate ester; cyclic acetal; dichlorobenzene; oligosaccharide derivative; ortho ester; oxaspiro compound; phenols; tertiary alpha-hydroxy ketone | antimicrobial agent; bacterial metabolite |
| benzoylaconine | [no description available] | low | 0 | 0 | benzoate ester; bridged compound; diterpene alkaloid; organic heteropolycyclic compound; polyether; secondary alcohol; tertiary alcohol; tertiary amino compound; tetrol | phytotoxin; plant metabolite |
| deoxyaconitine | [no description available] | low | 0 | 0 | acetate ester; benzoate ester; bridged compound; diol; diterpene alkaloid; organic heteropolycyclic compound; polyether; secondary alcohol; tertiary amino compound | plant metabolite |
| benzoylmesaconine | [no description available] | low | 0 | 0 | benzoate ester; bridged compound; diterpene alkaloid; organic heteropolycyclic compound; polyether; secondary alcohol; tertiary alcohol; tertiary amino compound; tetrol | analgesic; antiinfective agent; plant metabolite |
| albiflorin | [no description available] | low | 0 | 0 | benzoate ester; beta-D-glucoside; bridged compound; gamma-lactone; monoterpene glycoside; secondary alcohol | neuroprotective agent; plant metabolite |
| brartemicin | [no description available] | low | 0 | 0 | benzoate ester; glycosyl glycoside derivative; resorcinols | antimicrobial agent; metabolite |
| brasilicardin a | [no description available] | low | 0 | 0 | benzoate ester; carbotricyclic compound; diterpenoid; N-acetyl-D-glucosaminide; non-proteinogenic alpha-amino acid; phenols | antimicrobial agent; antineoplastic agent; bacterial metabolite; immunosuppressive agent |
| paeoniflorigenone | [no description available] | low | 0 | 0 | alicyclic ketone; benzoate ester; bridged compound; cyclic acetal; lactol; monoterpenoid | neuromuscular agent; plant metabolite |
| 4-[[(4-oxo-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-2-yl)thio]methyl]benzoic acid methyl ester | [no description available] | low | 0 | 0 | benzoate ester |
| Article | Year |
|---|---|
| In vitro cytotoxicity of melleolide antibiotics: structural and mechanistic aspects. Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue: 7 | 2011 |
| [information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | |