Page last updated: 2024-12-10

ah 11110a

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

AH 11110A: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID9907616
MeSH IDM0397643

Synonyms (18)

Synonym
ah 11110, >98% (hplc), solid
ah 11110 hydrochloride
ah 11110
179388-65-9
4-imino-1-(2-phenylphenoxy)-4-piperidinebutan-2-ol hydrochloride
ah-11110
gtpl8461
4-imino-1-(2-phenylphenoxy)-4-piperidin-1-ylbutan-2-ol hydrochloride
AKOS024458726
DTXSID90432694
SR-01000597846-1
sr-01000597846
Q27074354
1-piperidinepropanol, alpha-[([1,1'-biphenyl]-2-yloxy)methyl]-gamma-imino-, hydrochloride (1:1)
ah 11110a
ah11110a;ah-11110a
4-imino-1-(2-phenylphenoxy)-4-piperidin-1-ylbutan-2-ol;hydrochloride
1-piperidinepropanol,a-[([1,1'-biphenyl]-2-yloxy)methyl]-g-imino-,hydrochloride(1:1)

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" Additionally, AH11110A enhanced the general contractility of rat vas deferens, produced a bell-shaped dose-response curve of vasodilation in perfused rat kidney, and its antagonism in most other tissues was not simply competitive."( Failure of AH11110A to functionally discriminate between alpha(1)-adrenoceptor subtypes A, B and D or between alpha(1)- and alpha(2)-adrenoceptors.
Eltze, M; Grebe, T; König, H; Ullrich, B, 2001
)
0.31
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID1346000Human alpha1B-adrenoceptor (Adrenoceptors)1996The Journal of pharmacology and experimental therapeutics, Jul, Volume: 278, Issue:1
Structure activity relationships of a series of buspirone analogs at alpha-1 adrenoceptors: further evidence that rat aorta alpha-1 adrenoceptors are of the alpha-1D-subtype.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]