Compounds > 5-bromosalicylaldehyde
Page last updated: 2024-11-06

5-bromosalicylaldehyde

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

5-bromosalicylaldehyde is an organic compound that serves as a versatile building block in organic synthesis. It is often used as a precursor to various pharmaceuticals, agrochemicals, and other fine chemicals. Its unique structure, containing both an aldehyde and a bromine substituent on the salicylaldehyde scaffold, allows for diverse chemical transformations and functionalizations. Synthesis methods typically involve bromination of salicylaldehyde using appropriate reagents and reaction conditions. 5-bromosalicylaldehyde's importance lies in its potential to access a range of bioactive compounds and its role as a key intermediate in various chemical processes. Research on 5-bromosalicylaldehyde focuses on exploring its synthetic applications, biological activity, and potential use in the development of novel therapeutic agents and functional materials.'

5-bromosalicylaldehyde: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID72863
CHEMBL ID207194
SCHEMBL ID79219
MeSH IDM000609397

Synonyms (54)

Synonym
1761-61-1
benzaldehyde, 5-bromo-2-hydroxy-
5-bromo-salicyclaldehyde
nsc-7310
5-bromo-2-hydroxybenzaldehyde
2-hydroxy-5-bromobenzaldehyde
salicylaldehyde, 5-bromo-
5-bromosalicylaldehyde
nsc7310
nsc9258
nsc-9258
5-bromo-2-hydroxy-benzaldehyde
inchi=1/c7h5bro2/c8-6-1-2-7(10)5(3-6)4-9/h1-4,10
5-bromosalicylaldehyde, 98%
nsc 9258
ai3-31310
einecs 217-167-2
nsc 7310
STK198695
AC-4361
B0893
AC-907/34104064
AKOS000118780
CHEMBL207194
FT-0695659
A3911
0z65a0a8ce ,
unii-0z65a0a8ce
BP-12732
PS-4147
AM20030167
F3099-6597
3-bromo-6-hydroxybenzaldehyde
4-bromo-2-formylphenol
FT-0620170
SCHEMBL79219
bdbm111013
us8614253, .3-44
2-hydroxy-5-bromo benzaldehyde
5-bromo-salicylaldehyde
5-bromo salicylaldehyde
5-bromo-2-hydroxy benzaldehyde
STR00148
DTXSID8022165
J-516942
mfcd00003330
J-011167
CS-D1395
SY001440
17691-61-1
AC8025
Q27251066
EN300-18186
Z57313901
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID266443Inhibition of human recombinant PRL-3 up to 50 uM2006Bioorganic & medicinal chemistry letters, Jun-01, Volume: 16, Issue:11
Synthesis and biological evaluation of rhodanine derivatives as PRL-3 inhibitors.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's2 (33.33)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 36.49

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index36.49 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index5.12 (4.65)
Search Engine Demand Index41.67 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (36.49)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
taurine
[no description available]		2.5420amino sulfonic acid;
zwitterion		antioxidant;
Escherichia coli metabolite;
glycine receptor agonist;
human metabolite;
mouse metabolite;
nutrient;
radical scavenger;
Saccharomyces cerevisiae metabolite
vanillin
Vanilla: A plant genus of the family ORCHIDACEAE that is the source of the familiar flavoring used in foods and medicines (FLAVORING AGENTS).		2.1110benzaldehydes;
monomethoxybenzene;
phenols		anti-inflammatory agent;
anticonvulsant;
antioxidant;
flavouring agent;
plant metabolite
pentamidine
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.. pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.		2.0310aromatic ether;
carboxamidine;
diether		anti-inflammatory agent;
antifungal agent;
calmodulin antagonist;
chemokine receptor 5 antagonist;
EC 2.3.1.48 (histone acetyltransferase) inhibitor;
NMDA receptor antagonist;
S100 calcium-binding protein B inhibitor;
trypanocidal drug;
xenobiotic
2-vanillin
ortho-vanillin : A member of the class of benzaldehydes that is salicylaldehyde substituted by a methoxy group at position 3.		2.1110benzaldehydes;
guaiacols		antimutagen;
plant metabolite
hydrazine
diamine : Any polyamine that contains two amino groups.		2.1110azane;
hydrazines		EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
5-chloro-salicylaldehyde
5-chloro-salicylaldehyde: structure in first source		2.1110
palladium
Palladium: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.. palladium : Chemical element (nickel group element atom) with atomic number 46.		2.2510metal allergen;
nickel group element atom;
platinum group metal atom
bromine
Bromine: A halogen with the atomic symbol Br, atomic number 35, and atomic weight 79.904. It is a volatile reddish-brown liquid that gives off suffocating vapors, is corrosive to the skin, and may cause severe gastroenteritis if ingested.		2.1110diatomic bromine
4-methoxybenzohydrazide
4-methoxybenzohydrazide: structure in first source		2.1110
melphalan
Melphalan: An alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - MELPHALAN, the racemic mixture - MERPHALAN, and the dextro isomer - MEDPHALAN; toxic to bone marrow, but little vesicant action; potential carcinogen.. melphalan : A phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-position on the phenyl ring.		2.4110L-phenylalanine derivative;
nitrogen mustard;
non-proteinogenic L-alpha-amino acid;
organochlorine compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent
gallium
Gallium: A rare, metallic element designated by the symbol, Ga, atomic number 31, and atomic weight 69.72.. gallium atom : A metallic element predicted as eka-aluminium by Mendeleev in 1870 and discovered by Paul-Emile Lecoq de Boisbaudran in 1875. Named in honour of France (Latin Gallia) and perhaps also from the Latin gallus cock, a translation of Lecoq.		7.4110boron group element atom
ConditionIndicatedRelationship StrengthStudiesTrials