3-cyanocoumarin: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 203763 |
| CHEMBL ID | 1767304 |
| SCHEMBL ID | 622794 |
| MeSH ID | M0444265 |
| Synonym |
|---|
| 3-cyanocoumarin |
| 2h-1-benzopyran-3-carbonitrile, 2-oxo- |
| 2-oxo-2h-1-benzopyran-3-carbonitrile |
| brn 0142122 |
| 3-cyano-coumarin |
| 3-cyanocoumarin, 97% |
| MAYBRIDGE1_000749 |
| OPREA1_612712 |
| HMS543K01 |
| 2-oxochromene-3-carbonitrile |
| AKOS002679478 |
| A809132 |
| CHEMBL1767304 |
| EN300-92215 |
| coumarin, 3-cyano- |
| 2-oxo-chromene-3-carbonitrile |
| 15119-34-3 |
| 2h-1-benzopyran-3-carbonitrile,2-oxo- |
| 2-oxo-2h-chromene-3-carbonitrile , |
| FT-0637185 |
| STL363562 |
| SCHEMBL622794 |
| c10h5no2 |
| Z276153038 |
| QKJALQPLNMEDAV-UHFFFAOYSA-N |
| coumarin-3-carbonitrile |
| C2830 |
| DTXSID10164728 |
| mfcd00115699 |
| sr-01000397985 |
| SR-01000397985-1 |
| J-008787 |
| CS-0181815 |
| AS-43894 |
| ?3-cyanocoumarin |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID592670 | Inhibition of amyloid beta (1 to 40) monomer aggregation assessed as reduction in plateau fluorescence by thioflavin T based fluorometric assay | 2011 | Bioorganic & medicinal chemistry, Apr-15, Volume: 19, Issue:8 | Inhibition of amyloid-β aggregation by coumarin analogs can be manipulated by functionalization of the aromatic center. |
| AID1460083 | Agonist activity at GPR35 in human HT-29 cells in presence of antagonist ML-145 by DMR assay | 2017 | Journal of medicinal chemistry, 01-12, Volume: 60, Issue:1 | Discovery of 2H-Chromen-2-one Derivatives as G Protein-Coupled Receptor-35 Agonists. |
| AID592669 | Inhibition of amyloid beta (1 to 40) monomer aggregation assessed as lag time extension by thioflavin T based fluorometric assay relative to control | 2011 | Bioorganic & medicinal chemistry, Apr-15, Volume: 19, Issue:8 | Inhibition of amyloid-β aggregation by coumarin analogs can be manipulated by functionalization of the aromatic center. |
| AID1460081 | Agonist activity at GPR35 in human HT-29 cells by DMR assay | 2017 | Journal of medicinal chemistry, 01-12, Volume: 60, Issue:1 | Discovery of 2H-Chromen-2-one Derivatives as G Protein-Coupled Receptor-35 Agonists. |
| AID1159607 | Screen for inhibitors of RMI FANCM (MM2) intereaction | 2016 | Journal of biomolecular screening, Jul, Volume: 21, Issue:6 | A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.51) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||