Page last updated: 2024-11-05

1,4-diethylbenzene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

1,4-Diethylbenzene is an aromatic hydrocarbon with the chemical formula C10H14. It is a colorless liquid with a characteristic odor. 1,4-Diethylbenzene can be synthesized through various methods, including the Friedel-Crafts alkylation of benzene with ethyl chloride or ethyl bromide in the presence of a Lewis acid catalyst. It is also a byproduct of the catalytic cracking of petroleum. 1,4-Diethylbenzene is primarily used as a solvent and as an intermediate in the production of other chemicals. It is a component of gasoline and jet fuel, and it is also used in the manufacture of resins, polymers, and pharmaceuticals. The environmental effects of 1,4-diethylbenzene are not well-studied, but it is known to be a flammable and volatile compound. It is also known to be irritating to the skin, eyes, and respiratory tract. 1,4-Diethylbenzene is a relatively unreactive compound, but it can undergo oxidation, halogenation, and nitration reactions. It is studied for its potential use as a fuel additive and as a precursor to other valuable chemicals. Research on 1,4-diethylbenzene focuses on its synthesis, reactivity, environmental impact, and potential applications. The compound is also used in the synthesis of certain polymers and resins.'

Cross-References

ID SourceID
PubMed CID7734
CHEMBL ID3187283
CHEBI ID34062
MeSH IDM0178263

Synonyms (42)

Synonym
BIDD:ER0274
AKOS009031101
EN300-21456
einecs 203-265-2
p-ethylethylbenzene
hsdb 4083
benzene, p-diethyl-
benzene, 1,4-diethyl-
p-diethylbenzene
1,4-diethylbenzene
inchi=1/c10h14/c1-3-9-5-7-10(4-2)8-6-9/h5-8h,3-4h2,1-2h
105-05-5
1,4-diethylbenzene, 96%
D0479
NCGC00248539-01
cas-105-05-5
NCGC00257700-01
dtxsid4026711 ,
dtxcid706711
tox21_200146
0psm16x42d ,
unii-0psm16x42d
ec 203-265-2
FT-0606869
1,4-diethylbenzene-d14
1,4-diethylbenzene [hsdb]
diethylbenzene, 1,4-
diethylbenzene, p-
para-diethylbenzene
CHEBI:34062 ,
Q-200084
CHEMBL3187283
1219803-64-1
mfcd00009264
1,4-diethylbenzene, analytical standard
1,4-diethylbenzene 100 microg/ml in methanol
benzene, 1,4-diethyl-; benzene, p-diethyl- (8ci); p-xylene, ?,?'-dimethyl- (7ci); 1,4-diethylbenzene; p-diethylbenzene; p-ethylethylbenzene
1,4-diethyl-benzene
Q27115785
AS-13583
D88164
p-diethylbenzene 1,4-diethylbenzene

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" Fifteen metabolites were found in the urine of rats dosed with a single intraperitoneal injection of 1,4-diethenylbenzene (300 mg/kg)."( Biotransformation of diethenylbenzenes. II. Metabolic pattern of 1,4-diethenylbenzene.
Linhart, I; Novák, J, 1990
)
0.28
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
benzenesAny benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 33.45

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index33.45 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.20 (4.65)
Search Engine Demand Index42.09 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (33.45)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]