tyropanoate profile

Tyropanoate: A diagnostic aid as a radiopaque medium in cholecystography. [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	5611
CHEMBL ID	1201261
CHEBI ID	135862
SCHEMBL ID	2788021
MeSH ID	M0022199

Synonyms (34)

Synonym
27293-82-9
tyropanoic acid
benzenepropanoic acid, .alpha.-ethyl-2,4, {6-triiodo-3-[(1-oxobutyl)amino]-,} monosodium salt
tyropanoate sodium(usan
hydrocinnamic acid, 3-butyramido-.alpha.-ethyl-2,4, 6-triiodo-, monosodium salt
hydrocinnamic acid, 3-butyramido-.alpha.-ethyl-2,4,6-triiodo-
hydrocinnamic acid, 3-butyramido-.alpha.-ethyl-2,4,6-triiodo-, sodium salt
2-(3-(butyrylamino)-2,4,6-triiodobenzyl)butanoic acid
2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methyl]butanoic acid
sodium 3-butyramido-.alpha.-ethyl-2,4,6-triiodohydrocinnamate
sodium tyropanoate (usan)
tyropanoate
CHEBI:135862
2-[[3-(butanoylamino)-2,4,6-triiodophenyl]methyl]butanoic acid
CHEMBL1201261
einecs 248-389-8
unii-4f05v145yr
4f05v145yr ,
2-(3-(butyrylamino)-2,4,6-triiodobenzyl)butyric acid
tyropanic acid
benzenepropanoic acid, alpha-ethyl-2,4,6-triiodo-3-((1-oxobutyl)amino)-
acidum tyropanoicum
benzenepropanoic acid, a-ethyl-2,4,6-triiodo-3-[(1-oxobutyl)amino]-
tyropanoate [vandf]
tyropanoic acid [who-dd]
benzenepropanoic acid, .alpha.-ethyl-2,4,6-triiodo-3-((1-oxobutyl)amino)-
DTXSID5048269
SCHEMBL2788021
DB09340
Q6587055
2-(3-butyramido-2,4,6-triiodobenzyl)butanoic acid
STARBLD0000838
EN300-18568448
2-[(3-butanamido-2,4,6-triiodophenyl)methyl]butanoic acid

Class	Description
monocarboxylic acid	An oxoacid containing a single carboxy group.
benzenes	Any benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	25 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	5 (15.63%)	5.53%
Reviews	1 (3.13%)	6.00%
Case Studies	1 (3.13%)	4.05%
Observational	0 (0.00%)	0.25%
Other	25 (78.13%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
iodine Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.. diiodine : Molecule comprising two covalently bonded iodine atoms with overall zero charge..	2.36	2	0	diatomic iodine	nutrient
iopanoic acid Iopanoic Acid: Radiopaque medium used as diagnostic aid.	7.3	13	3	monocarboxylic acid
iodipamide Iodipamide: A water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.. adipiodone : An organoiodine compound that is 3-amino-2,4,6-triiodobenzoic acid in which one of the amino hydrogens is substituted by a 6-(3-carboxy-2,4,6-triiodoanilino)-6-oxohexanoyl group. It is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.	1.95	1	0	benzoic acids; organoiodine compound; secondary carboxamide	radioopaque medium
ipodate Ipodate: Ionic monomeric contrast media. Usually the sodium or calcium salts are used for examination of the gall bladder and biliary tract. (From Martindale, The Extra Pharmacopoeia, 30th ed, p704)	3.57	9	0
sulfobromophthalein Sulfobromophthalein: A phenolphthalein that is used as a diagnostic aid in hepatic function determination.	2.65	3	0	2-benzofurans; organobromine compound; organosulfonic acid; phenols	dye
thyroxine Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.. thyroxine : An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.	2.65	3	0	2-halophenol; iodophenol; L-phenylalanine derivative; non-proteinogenic L-alpha-amino acid; thyroxine zwitterion; thyroxine	antithyroid drug; human metabolite; mouse metabolite; thyroid hormone
triiodothyronine Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.. 3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.	2.36	2	0	2-halophenol; amino acid zwitterion; iodophenol; iodothyronine	human metabolite; mouse metabolite; thyroid hormone
acetrizoic acid Acetrizoic Acid: An iodinated radiographic contrast medium used as acetrizoate sodium in HYSTEROSALPINGOGRAPHY.	1.96	1	0	aminobenzoic acid
ioglycamic acid Ioglycamic Acid: A radiopaque medium. It is a mixture of its meglumine and sodium salts and is used to visualize the biliary tract.	1.95	1	0	amidobenzoic acid
methimazole Methimazole: A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme.. methimazole : A member of the class of imidazoles that it imidazole-2-thione in which a methyl group replaces the hydrogen which is attached to a nitrogen.	1.96	1	0	1,3-dihydroimidazole-2-thiones	antithyroid drug
thyronines Thyronines: A group of metabolites derived from THYROXINE and TRIIODOTHYRONINE via the peripheral enzymatic removal of iodines from the thyroxine nucleus. Thyronine is the thyroxine nucleus devoid of its four iodine atoms.. thyronine : A tyrosine derivative where the phenolic hydrogen of tyrosine is substituted by 4-hydroxyphenyl.	1.96	1	0	thyronine
buniodyl buniodyl: RN given refers to parent cpd	2.34	2	0	cinnamic acids
3',5'-diiodothyronine 3',5'-diiodothyronine: RN given refers to (DL)-isomer	1.96	1	0	phenylalanine derivative

Condition	Relationship Strength	Studies
Gall Bladder Diseases [description not available]	2.65	3
Biliary Tract Diseases Diseases in any part of the BILIARY TRACT including the BILE DUCTS and the GALLBLADDER.	1.96	1
Bile Duct Obstruction, Extrahepatic [description not available]	1.96	1
Empyema, Gall Bladder [description not available]	1.96	1
Cholecystitis Inflammation of the GALLBLADDER; generally caused by impairment of BILE flow, GALLSTONES in the BILIARY TRACT, infections, or other diseases.	1.96	1
Acute Edematous Pancreatitis [description not available]	1.96	1
Acute Disease Disease having a short and relatively severe course.	1.96	1
Pancreatitis INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.	6.96	1
Acute Kidney Failure [description not available]	1.95	1
Acute Kidney Injury Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.	1.95	1
Basedow Disease [description not available]	1.96	1
Graves Disease A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).	1.96	1

tyropanoate

Description

Cross-References

Synonyms (34)

Research Excerpts

Drug Classes (2)

Research

Studies (25)

Study Types

tyropanoate

Description

Cross-References

Synonyms (34)

Research Excerpts

Drug Classes (2)

Research

Studies (25)

Study Types

Related Drugs (13)

Related Conditions (12)