Page last updated: 2024-12-07

4-chloro-5-sulfamoylanthranilic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

4-chloro-5-sulfamoylanthranilic acid: hydrolysis product of furosemide [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID76523
CHEBI ID143338
SCHEMBL ID3040620
MeSH IDM0056119

Synonyms (35)

Synonym
cqe8131sf0 ,
unii-cqe8131sf0
einecs 221-408-7
4-chloro-5-sulfamoylanthranilic acid
2-amino-5-(aminosulphonyl)-4-chlorobenzoic acid
3086-91-7
2-amino-5-aminosulfonyl-4-chlorobenzoic acid
desfurylmethylfurosemide
4-chloro-5-sulfamoyl-anthranilic acid
saluamine
FT-0650659
CHEBI:143338
2-amino-4-chloro-5-sulfamoylbenzoic acid
2-amino-5-(aminosulfonyl)-4-chlorobenzoic acid
AKOS015995696
anthranilic acid, 4-chloro-5-sulfamoyl-
benzoic acid, 2-amino-5-(aminosulfonyl)-4-chloro-
4-chloro-5-sulfamylanthranilic acid
furosemide impurity c [ep impurity]
SCHEMBL3040620
STL481759
DTXSID60184875
J-018174
2-amino-4-chloro-5-sulphamoylbenzoic acid
furosemide imp. c (ep); furosemide usp related compound b; furosemide usp rc b; 2-amino-4-chloro-5-sulphamoylbenzoic acid; furosemide related compound b; furosemide impurity c
furosemide impurity c
Q27275645
2-amino-5-aminosulfonyl-4-chlorobenzoicacid
D94641
2-amino-4-chloro-5-sulfamoylbenzoic acid 100 microg/ml in acetonitrile
2-amino-4-chloro-5-sulfamoylbenzoicacid
AS-76514
EN300-6739398
CS-0323685
B2694-106506

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
"The objectives of this study were to qualitatively and quantitatively compare the metabolism, pharmacokinetics, and bioavailability of furosemide in healthy volunteers after intravenous and oral administration."( Absorption and disposition of furosemide in healthy volunteers, measured with a metabolite-specific assay.
Benet, LZ; Lin, ET; Smith, DE,
)
0.13
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (2)

ClassDescription
sulfonamideAn amide of a sulfonic acid RS(=O)2NR'2.
benzenesAny benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19909 (90.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 31.88

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index31.88 (24.57)
Research Supply Index2.71 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index25.55 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (31.88)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (7.69%)5.53%
Reviews1 (7.69%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (84.62%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]