fukiic acid: RN given for (S-(R*,S*))-isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 161871 |
| CHEBI ID | 166659 |
| MeSH ID | M0298600 |
| Synonym |
|---|
| fukiic acid |
| 35388-56-8 |
| CHEBI:166659 |
| (2r,3s)-2-[(3,4-dihydroxyphenyl)methyl]-2,3-dihydroxybutanedioic acid |
| racemic fukiic acid |
| (2r,3s)-2-[(3,4-dihydroxyphenyl)methyl]-2,3-dihydroxy-butanedioic acid |
| unii-97f6dhv594 |
| butanedioic acid, 2-((3,4-dihydroxyphenyl)methyl)-2,3-dihydroxy-, (2r,3s)- |
| 97f6dhv594 , |
| butanedioic acid, 2-((3,4-dihydroxyphenyl)methyl)-2,3-dihydroxy-, (s-(r*,s*))- |
| 2-[(3,4-dihydroxyphenyl)methyl]-2,3-dihydroxybutanedioic acid, 9ci |
| 3,4-dihydroxybenzyltartaric acid |
| Q27272009 |
| DTXSID90956805 |
| 2-[(3,4-dihydroxyphenyl)methyl]-2,3-dihydroxybutanedioic acid |
rac-Fukiic acid was found to be a potent inhibitor of HIV-1 integrase but did not reveal any antiviral activity in the MT-4 cells assay.
| Excerpt | Reference | Relevance |
|---|---|---|
| "rac-Fukiic acid was found to be a potent inhibitor of HIV-1 integrase but did not reveal any antiviral activity in the MT-4 cells assay." | ( The total synthesis of fukiic acid, an HIV-1 integrase inhibitor. Bailly, F; Cotelle, P; Debyser, Z; Mbemba, G; Mouscadet, JF; Queffélec, C; Witvrouw, M, 2008) | 1.14 |
| Class | Description |
|---|---|
| benzenes | Any benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives. |
| monocarboxylic acid | An oxoacid containing a single carboxy group. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (19.99) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||