vaticanol C: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 49866362 |
| CHEMBL ID | 1224887 |
| MeSH ID | M0430791 |
| Synonym |
|---|
| CHEMBL1224887 , |
| vaticanol c |
| bdbm50362646 |
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 (µMol) | 21.2000 | 0.0004 | 1.8773 | 10.0000 | AID641150 |
| Sucrase-isomaltase, intestinal | Rattus norvegicus (Norway rat) | IC50 (µMol) | 94.2000 | 0.0400 | 1.8483 | 10.0000 | AID641148 |
| Lysosomal alpha-glucosidase | Rattus norvegicus (Norway rat) | IC50 (µMol) | 140.0000 | 0.0800 | 2.5061 | 9.8500 | AID641146 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID641148 | Inhibition of alpha-glucosidase activity of sucrase in rat small intestinal brush border membrane fraction using maltose as substrate after 30 mins | 2012 | Bioorganic & medicinal chemistry, Jan-15, Volume: 20, Issue:2 | Antidiabetogenic oligostilbenoids and 3-ethyl-4-phenyl-3,4-dihydroisocoumarins from the bark of Shorea roxburghii. |
| AID504234 | Cytotoxicity against human foreskin fibroblast at 1 uM | 2010 | Journal of natural products, Sep-24, Volume: 73, Issue:9 | Resveratrol oligomers from Vatica albiramis. |
| AID641150 | Inhibition of rat lens aldose reductase using DL-glyceraldehyde as substrate after 30 mins by fluorescence microplate reader analysis | 2012 | Bioorganic & medicinal chemistry, Jan-15, Volume: 20, Issue:2 | Antidiabetogenic oligostilbenoids and 3-ethyl-4-phenyl-3,4-dihydroisocoumarins from the bark of Shorea roxburghii. |
| AID641146 | Inhibition of alpha-glucosidase activity of maltase in rat small intestinal brush border membrane fraction using maltose as substrate after 30 mins | 2012 | Bioorganic & medicinal chemistry, Jan-15, Volume: 20, Issue:2 | Antidiabetogenic oligostilbenoids and 3-ethyl-4-phenyl-3,4-dihydroisocoumarins from the bark of Shorea roxburghii. |
| AID504233 | Antiinflammatory activity in human foreskin fibroblast assessed as inhibition of IL-1-beta-induced MMP1 production at 1 uM treated for 24 hrs before IL1-beta challenge measured after 24 hrs by Western blot analysis | 2010 | Journal of natural products, Sep-24, Volume: 73, Issue:9 | Resveratrol oligomers from Vatica albiramis. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.15) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||