Page last updated: 2024-12-10
thioformamide
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
thiocarboxamide : Any primary amide having its amide oxygen replaced by sulfur. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 3005587 |
| MeSH ID | M0054182 |
Synonyms (22)
| Synonym |
|---|
| methanethioamide |
| hcsnh2 |
| thioformamide , |
| 115-08-2 |
| A803369 |
| einecs 204-063-7 |
| g525tln0e7 , |
| unii-g525tln0e7 |
| AKOS006228709 |
| methanimidothioic acid |
| methanethioamide (9ci) |
| AB42997 |
| thioformamide [mi] |
| thiocarboxamide |
| CYEBJEDOHLIWNP-UHFFFAOYSA-N |
| thioforamide |
| DTXSID00150918 |
| J-521698 |
| is8 , |
| iminomethyl thiol |
| AMY33487 |
| Q27278759 |
Research Excerpts
Toxicity
| Excerpt | Reference | Relevance |
|---|---|---|
| " On the other hand, the target organ (the kidney or liver) and the toxic potency of 4-methylthiazoles were markedly altered with the type of substituents at the 2-position." | ( Possible role of thioformamide as a proximate toxicant in the nephrotoxicity of thiabendazole and related thiazoles in glutathione-depleted mice: structure-toxicity and metabolic studies. Kawazoe, S; Mizutani, T; Yoshida, K, ) | 0.47 |
Dosage Studied
| Excerpt | Relevance | Reference |
|---|---|---|
| " Evidence for this hypothesis was provided by the results that thioformamide and tert-butylglyoxal as the accompanying fragment were identified as urinary metabolites in mice dosed with 4-tert-butylthiazole and that thioformamide caused a marked increase in SUN concentration when administered to mice in combination with BSO." | ( Possible role of thioformamide as a proximate toxicant in the nephrotoxicity of thiabendazole and related thiazoles in glutathione-depleted mice: structure-toxicity and metabolic studies. Kawazoe, S; Mizutani, T; Yoshida, K, ) | 0.71 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Research
Studies (8)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 28.43
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (28.43) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (11.11%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (88.89%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||