Compounds > rhizobitoxine
Page last updated: 2024-12-11

rhizobitoxine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

rhizobitoxine: toxic substance found in extracts of R. japonicum; believed to be helpful in protecting soybean roots from M. phaseolina infection [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID6436603
SCHEMBL ID14753555
MeSH IDM0123349

Synonyms (13)

Synonym
rhizobitoxine
(e,2s)-2-amino-4-[(2r)-2-amino-3-hydroxypropoxy]but-3-enoic acid
unii-h4jex49o4k
37658-95-0
3-butenoic acid, 2-amino-4-(2-amino-3-hydroxypropoxy)-, (s-(r*,s*-(e)))-
h4jex49o4k ,
SCHEMBL14753555
(2s,3e)-2-amino-4-[(2r)-2-amino-3-hydroxypropoxy]but-3-enoate
rhizobitoxin
rhizobutoxine
(2s,3e)-2-amino-4-((2r)-2-amino-3-hydroxypropoxy)-3-butenoic acid
3-butenoic acid, 2-amino-4-((2r)-2-amino-3-hydroxypropoxy)-, (2s,3e)
C21887

Research Excerpts

Overview

Rhizobitoxine is a phytotoxin synthesized by some strains of the legume symbiont genus Bradyrhizobium and the plant pathogen Pseudomonas andropogonis.

ExcerptReferenceRelevance
"Rhizobitoxine is a phytotoxin synthesized by some strains of the legume symbiont genus Bradyrhizobium and the plant pathogen Pseudomonas andropogonis. "( Rapid and sensitive assay for the phytotoxin rhizobitoxine.
Peters, NK; Ruan, X, 1991)		1.98

Actions

ExcerptReferenceRelevance
"Rhizobitoxine did not cause cell death at a concentration sufficient to eliminate hydrogenase expression."( Rhizobitoxine inhibition of hydrogenase synthesis in free-living Bradyrhizobium japonicum.
Asami, T; Fukai, K; Minamisawa, K, 1990)		2.44

Dosage Studied

ExcerptRelevanceReference
" Dosage response curves with rhizobitoxine showed it to be antifungal."( Role of rhizobitoxine in protecting soybean roots from Macrophomina phaseolina infection.
Chakraborty, U; Purkayastha, RP, 1984)		0.99
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (17)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (5.88)18.7374
1990's4 (23.53)18.2507
2000's10 (58.82)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 22.63

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index22.63 (24.57)
Research Supply Index2.94 (2.92)
Research Growth Index4.99 (4.65)
Search Engine Demand Index21.17 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (22.63)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (11.11%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other16 (88.89%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
1-aminocyclopropane-1-carboxylic acid
1-aminocyclopropanecarboxylic acid : A non-proteinogenic alpha-amino acid consisting of cyclopropane having amino and carboxy substituents both at the 1-position.		210amino acid zwitterion;
monocarboxylic acid;
non-proteinogenic alpha-amino acid		ethylene releasers;
plant metabolite
hydrogen
Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.. dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.		2.0310elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
nitrates
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.		1.9810monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species
chloramphenicol
Amphenicol: Chloramphenicol and its derivatives.		1.9710C-nitro compound;
carboxamide;
diol;
organochlorine compound		antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor
methionine
Methionine: A sulfur-containing essential L-amino acid that is important in many body functions.. methionine : A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4.		7.0310aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid		antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical
ethylene
Plastipore: high density polyethylene sponge biocompatible material; used as posts in dental bridges		3.5120alkene;
gas molecular entity		plant hormone;
refrigerant
homoserine
homoserine : An alpha-amino acid that is glycine substituted at the alpha-position by a 2-hydroxyethyl group.. L-homoserine : The L-enantiomer of homoserine.		2.0310amino acid zwitterion;
homoserine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite
ConditionIndicatedRelationship StrengthStudiesTrials