Page last updated: 2024-10-15
repin
Description
repin: isolated from knapweed Acroptilon repens; causes equine nigropallidial encephalomacia; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
---|---|
PubMed CID | 146156429 |
MeSH ID | M0177241 |
Synonyms (2)
Synonym |
---|
repin |
11024-67-2 |
Research Excerpts
Overview
Repin is a sesquiterpene lactone found in Centaurea solstitialis, a plant responsible for Parkinson-like disease in horses.
Excerpt | Reference |
---|---|
"Repin is a sesquiterpene lactone found in Centaurea solstitialis, a plant responsible for Parkinson-like disease in horses. " | ( Effect of various pretreatments on the hypothermic activity of repin in naive rats. Akbar, S; Fries, DS; Malone, MH, 1995) |
Toxicity
Excerpt | Reference |
---|---|
" We show in this study that repin is highly toxic to C57BL/6J mice and Sprague-Dawley rats and acutely induces uncoordinated locomotion associated with postural tremors, hypothermia, and inability to respond to sonic and tactile stimuli." | ( Repin-induced neurotoxicity in rodents. Choi, BH; Han, B; Kim, RC; Robles, M; Santa Cruz, K, 1998) |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Research
Studies (13)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 4 (30.77) | 18.7374 |
1990's | 4 (30.77) | 18.2507 |
2000's | 3 (23.08) | 29.6817 |
2010's | 1 (7.69) | 24.3611 |
2020's | 1 (7.69) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 15 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |