Phenyltriethoxysilane (PTES) is a colorless liquid organosilicon compound with the formula C12H18O3Si. It is a key precursor in the synthesis of various materials, including siloxanes, polymers, and ceramics. PTES is commonly synthesized through the reaction of phenylmagnesium bromide with tetraethyl orthosilicate. Its high reactivity makes it suitable for use in sol-gel processing, where it undergoes hydrolysis and condensation reactions to form silica-based materials. PTES has gained significant attention due to its ability to impart unique properties to materials, such as hydrophobicity, improved mechanical strength, and enhanced thermal stability. It is widely studied in fields like materials science, nanotechnology, and biomedical engineering. PTES is used in the production of coatings, sealants, adhesives, and composites. Its ability to form strong bonds with various substrates, including glass, metal, and plastic, makes it a versatile component in these applications. Research on PTES focuses on developing new and efficient synthesis methods, exploring its applications in various fields, and understanding its reaction mechanisms. '
| ID Source | ID |
|---|---|
| PubMed CID | 13075 |
| CHEMBL ID | 3182111 |
| SCHEMBL ID | 29900 |
| MeSH ID | M0533404 |
| Synonym |
|---|
| nsc 77115 |
| triethoxy(phenyl)silane |
| einecs 212-305-8 |
| triethoxyfenylsilan [czech] |
| AKOS008901273 |
| nsc-77115 |
| phenyltriethoxysilane , |
| 780-69-8 |
| triethoxyphenylsilane |
| benzeneorthosiliconic acid, triethyl ester |
| nsc77115 |
| silane, triethoxyphenyl- |
| silane, phenyltriethoxy- |
| wln: 2o-si-r&o2&o2 |
| triethoxyphenylsilane, deposition grade, >=98% |
| triethoxyphenylsilane, 98% |
| P0735 |
| A839324 |
| NCGC00255717-01 |
| dtxsid8044462 , |
| cas-780-69-8 |
| dtxcid6024462 |
| tox21_302168 |
| ec 212-305-8 |
| benzene, (triethoxysilyl)- |
| qi310t2x15 , |
| unii-qi310t2x15 |
| triethoxyfenylsilan |
| FT-0632953 |
| S13700 |
| phenyltri(ethoxy)silane |
| SCHEMBL29900 |
| c12h20o3si |
| cp0320 |
| silane, phenyltriethoxy-, |
| tri(ethoxo)(phenyl)silane |
| CHEMBL3182111 |
| STL453639 |
| mfcd00009065 |
| E75918 |
| phenyltriethoxysilane; ptes |
| triethoxyphenyl-silane |
| triethoxy-phenyl-silane |
| FS-3831 |
| Q27287276 |
| CS-W020904 |
| EN300-6499593 |
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 24.5412 | 0.0010 | 19.4141 | 70.9645 | AID743191 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 6.8590 | 0.0003 | 23.4451 | 159.6830 | AID743065 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 61.1306 | 0.0023 | 19.5956 | 74.0614 | AID651631 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (28.58) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||