Page last updated: 2024-11-06

mandelamide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Mandelamide is a synthetic compound that has been studied for its potential therapeutic effects. It is an amide derivative of mandelic acid, a naturally occurring compound found in almonds and other fruits. Mandelamide is thought to have anti-inflammatory, analgesic, and antioxidant properties. Its mechanism of action is not fully understood, but it is believed to interact with certain receptors in the brain and immune system. Research on mandelamide is ongoing to explore its potential as a treatment for conditions such as pain, inflammation, and neurodegenerative diseases. However, it is important to note that mandelamide is not currently approved for medical use and further studies are needed to determine its safety and efficacy.'

mandelamide : A monocarboxylic acid amide that is phenylacetamide in which one of the benzylic hydrogens has been replaced by a hydroxy group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID73558
CHEBI ID136824
SCHEMBL ID159419
SCHEMBL ID13447497
MeSH IDM0055897

Synonyms (49)

Synonym
benzeneacetamide, alpha-hydroxy-
unii-i5m132opvn
i5m132opvn ,
nsc 16603
nsc-16603
mandelamide
4410-31-5
nsc16603
benzeneacetamide, .alpha.-hydroxy-
2-hydroxy-2-phenyl-acetamide
OPREA1_800185
mandelamide, 97%
AI-942/25034561
2-hydroxy-2-phenylacetamide
CHEBI:136824
FT-0654692
AKOS005254725
4358-86-5
A826487
(+/-)-mandelamide
dl-mandelamide
GEO-01646
FT-0625486
SCHEMBL159419
SCHEMBL13447497
mandelic acid amide
W-200373
2-phenylglycolamide
amygdalinamide
mandelamide, (+/-)-
dl-mandelic acid amide
.alpha.-hydroxybenzylcarboxamide
2-hydroxy-2-phenylacetamide #
mfcd00025495
dl-mandelamide 2-hydroxy-2-phenylacetamide
F17453
alpha-hydroxy-benzeneacetamide
FT-0773648
FT-0771772
DS-9906
AKOS032963157
Q27894789
benzeneacetamide, a-hydroxy-
(s)-a-hydroxybenzeneacetamide
(r)-a-hydroxybenzeneacetamide
SB45152
DTXSID901318287
CS-0149991
SY075683
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (3)

ClassDescription
monocarboxylic acid amideA carboxamide derived from a monocarboxylic acid.
benzyl alcoholsCompounds containing a phenylmethanol skeleton.
secondary alcoholA secondary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has two other carbon atoms attached to it.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (12)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (8.33)18.7374
1990's0 (0.00)18.2507
2000's8 (66.67)29.6817
2010's2 (16.67)24.3611
2020's1 (8.33)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 23.37

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index23.37 (24.57)
Research Supply Index2.56 (2.92)
Research Growth Index4.30 (4.65)
Search Engine Demand Index23.28 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (23.37)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other12 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]