| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
iodine
Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.. diiodine : Molecule comprising two covalently bonded iodine atoms with overall zero charge.. | 2.03 | 1 | 0 | diatomic iodine | nutrient |
amitrole
Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.. amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties. | 2.03 | 1 | 0 | aromatic amine;
triazoles | carotenoid biosynthesis inhibitor;
EC 1.11.1.6 (catalase) inhibitor;
herbicide |
erythrosine
Fluoresceins: A family of spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one derivatives. These are used as dyes, as indicators for various metals, and as fluorescent labels in immunoassays. | 2.03 | 1 | 0 | | |
dithiothreitol
1,4-dimercaptobutane-2,3-diol : A glycol that is butane-2,3-diol in which a hydrogen from each of the methyl groups is replaced by a thiol group.. 1,4-dithiothreitol : The threo-diastereomer of 1,4-dimercaptobutane-2,3-diol. | 2.03 | 1 | 0 | 1,4-dimercaptobutane-2,3-diol;
butanediols;
dithiol;
glycol;
thiol | chelator;
human metabolite;
reducing agent |
bromine
Bromine: A halogen with the atomic symbol Br, atomic number 35, and atomic weight 79.904. It is a volatile reddish-brown liquid that gives off suffocating vapors, is corrosive to the skin, and may cause severe gastroenteritis if ingested. | 2.03 | 1 | 0 | diatomic bromine | |
chrysomycin a
chrysomycin A: Streptomyces arenae; differs only in sugar moiety from gilvocarcin V | 3.17 | 1 | 0 | glycoside | |
diacetyldichlorofluorescein
diacetyldichlorofluorescein: stable storage form of dichlorofluorescein | 2.03 | 1 | 0 | | |
ay 25545
ravidomycin: isolated from mycelium of Streptomyces ravidus; structure given in first source. ravidomycin : A C-glycosylated naphthoisochromene derivative obtained from Streptomyces ravidus; exhibits antibiotic and anticancer properties. | 3.17 | 1 | 0 | acetate ester;
aromatic ether;
C-glycosyl compound;
naphthoisochromene;
olefinic compound;
phenols;
tertiary amine | antimicrobial agent;
antineoplastic agent;
bacterial metabolite |
pre-kinamycin
pre-kinamycin: intermediate in the biosynthetic pathway of kinamycin D; isolated from Streptomyces murayamaensis | 6.97 | 1 | 0 | | |
glycosides
[no description available] | 3.17 | 1 | 0 | | |
naphthoquinones
Naphthoquinones: Naphthalene rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups. | 3.55 | 2 | 0 | | |
landomycin a
landomycin A: structure given in first source; isolated from Streptomyces sp. | 3.17 | 1 | 0 | oligosaccharide | metabolite |
gilvocarcin v
gilvocarcin V: from Actinomycete DO-38; structure given in first source | 3.17 | 1 | 0 | | |
jadomycin a
jadomycin A: the aglycone of jadomycin B; structure in first source. jadomycin A : A organic heteropentacyclic compound that is 1,2,8,13-tetrahydro-3aH-benzo[b][1,3]oxazolo[3,2-f]phenanthridine which carries oxo groups at positions 2, 8 and 13, methyl group at position 5, hydroxy groups at positions 7 and 12, and a (2R)-butan-2-yl group at position 1. It is a mixture of epimers at the hemiaminal carbon (position 3a). | 3.17 | 1 | 0 | | |
jadomycin b
jadomycin B: structure given in first source; isolated from Streptomyces venezuelae. jadomycin B : A jadomycin that is jadomycin A in which the phenolic hydroxy group at position 12 has been converted to the corresponding 2,6-dideoxy-alpha-L-ribo-hexopyranoside, isolated from Streptomyces venezuelae. It exists as a diastereoisomeric mixture consisting of both 3aS and 3aR isomers. | 3.17 | 1 | 0 | glycoside;
jadomycin;
organic heteropentacyclic compound | antibacterial agent;
antineoplastic agent;
apoptosis inducer;
Aurora kinase inhibitor;
bacterial metabolite |
landomycin e
landomycin E: structure given in first source; isolated from Streptomyces sp. | 3.17 | 1 | 0 | oligosaccharide | |
warfarin
Warfarin: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.. warfarin : A racemate comprising equal amounts of (R)- and (S)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice.. 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one : A member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group. | 3.17 | 1 | 0 | benzenes;
hydroxycoumarin;
methyl ketone | |
chrysomycin b
chrysomycin B: structure given in first source | 3.17 | 1 | 0 | | |
kinamycin c
kinamycin C: an antineoplastic antibiotic that inhibits topoisomerase IIalpha; isolated from Streptomyces murayamaensis | 2.03 | 1 | 0 | kinamycin | |
kinamycin d
kinamycin D: structure given in first source | 1.99 | 1 | 0 | kinamycin | |
kinamycin a
kinamycin A: isolated from Streptomyces muragamaensis; RN in Chemline for Kinamycin B: 35303-13-0; RN for Kinamycin C: 35303-08-3; RN for Kinamycin D: 35303-14-1; RN given refers to parent cpd; structure | 3.17 | 1 | 0 | kinamycin | |
angucyclinone
angucyclinone: structure in first source | 3.17 | 1 | 0 | | |