isobornyl acrylate: causes contact dermatitis in some individuals; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 544160 |
| SCHEMBL ID | 26704 |
| MeSH ID | M0592490 |
| Synonym |
|---|
| isobornyl acrylate |
| acrylic acid isobornyl ester |
| 5888-33-5 |
| I0638 |
| FT-0627338 |
| AKOS022186219 |
| SCHEMBL26704 |
| 111821-21-7 |
| PSGCQDPCAWOCSH-UHFFFAOYSA-N |
| 2-propenoic acid, 1,7,7-trimethylbicyclo[2.2.1]hept-2-yl ester |
| sipomer iboa |
| 1,7,7-trimethylbicyclo[2.2.1]hept-2-yl acrylate # |
| ageflex iboa |
| 128946-20-3 |
| DTXSID00859939 |
| 1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol acrylate |
| isobornylacrylate |
| [(1s,4s)-1,7,7-trimethyl-6-bicyclo[2.2.1]heptanyl]prop-2-enoate |
Isobornyl acrylate is a chemical used in the glue of some of these devices and has been implicated as a frequent culprit allergen in patients.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Isobornyl acrylate is a chemical used in the glue of some of these devices and has been implicated as a frequent culprit allergen in patients who become sensitized to their device." | ( Isobornyl acrylate and diabetic devices steal the Show for the 2020 American Contact Dermatitis Society Allergen of the Year. Atwater, AR; Nath, N; Reeder, M, 2020) | 2.72 |
Isobornyl acrylate (IBOA) has recently been identified as one sensitizer in the FreeStyle Libre glucose sensor. Isobornly acrylated sensitization has been reported in only 2 cases.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Isobornyl acrylate (IBOA) has recently caused a number of cases of allergic contact dermatitis (ACD) from its use in medical devices. " | ( Solution using Stomahesive® wafers for allergic contact dermatitis caused by isobornyl acrylate in glucose monitoring sensors. Grills, C; Ng, KL; Nixon, RL; Tam, MM, 2022) | 2.39 |
| "Isobornyl acrylate (IBOA) has recently been identified as one sensitizer in the FreeStyle Libre glucose sensor. " | ( N,N-dimethylacrylamide-A new sensitizer in the FreeStyle Libre glucose sensor. Antelmi, A; Baeck, M; Bruze, M; Hamnerius, N; Herman, A; Isaksson, M; Mowitz, M; Pontén, A, 2019) | 1.96 |
| "Isobornyl acrylate sensitization has been reported in only 2 cases." | ( Two decades of occupational (meth)acrylate patch test results and focus on isobornyl acrylate. Christoffers, WA; Coenraads, PJ; Schuttelaar, ML, 2013) | 1.34 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 19 (38.00) | 24.3611 |
| 2020's | 31 (62.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.
| This Compound (45.02) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (1.96%) | 6.00% |
| Case Studies | 21 (41.18%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 29 (56.86%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||