hydrin 2: vasotocin C-terminally extented with glycine; not active on rat uterus or rat blood pressure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 3083001 |
| SCHEMBL ID | 15511428 |
| MeSH ID | M0167504 |
| Synonym |
|---|
| 122842-55-1 |
| oxytocin, 8-l-arginine-9a-glycine- |
| hydrin 2 |
| 2-[[(2s)-2-[[1-[(4r,7s,10s,16s,19r)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2s)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carbonyl]amino]-5-(di |
| SCHEMBL15511428 |
Hydrin 2 is a neurohypophysial peptide commonly implicated in rehydration of anurans.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Hydrin 2 is a neurohypophysial peptide commonly implicated in rehydration of anurans." | ( Effects of hydrin 2 on cutaneous electrical properties of Rana pipiens. Ford, NA; Robinson, GD, 2003) | 1.43 |
Hydrin 2 has not been found in neurosecretory granules of birds such as the goose. Hydrin 2 was found in the amphibian but not in the reptile.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Hydrin 2 has not been found in neurosecretory granules of birds such as the goose." | ( Occurrence of hydrin 2 (vasotocinyl-Gly), a new hydroosmotic neurohypophyseal peptide, in secretory granules isolated from the frog (Rana esculenta) neurointermediate pituitary. Acher, R; Chauvet, J; Chauvet, MT; Rouillé, Y, 1990) | 1.36 |
| "Hydrin 2 has been found in the amphibian but not in the reptile." | ( Evolutionary specificity of hydrins, new hydroosmotic neuropeptides: occurrence of hydrin 2 (vasotocinyl-Gly) in the toad Bufo marinus but not in the viper Vipera aspis. Acher, R; Chauvet, J; Chauvet, MT; Michel, G; Rouillé, Y, 1990) | 1.23 |
| "Hydrin 2 has been detected in several Ranidae (R." | ( Hydrins, hydroosmotic neurohypophysial peptides: osmoregulatory adaptation in amphibians through vasotocin precursor processing. Acher, R; Chauvet, J; Chauvet, MT; Michel, G; Rouillé, Y, 1989) | 1 |
| Excerpt | Relevance | Reference |
|---|---|---|
| " In a dose-response study, 10-fold increases in serosal hydrin 2 concentration triggered significant changes in TEP and Isc, with maximal responses observed at 10 ng/ml." | ( Effects of hydrin 2 on cutaneous electrical properties of Rana pipiens. Ford, NA; Robinson, GD, 2003) | 0.96 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 11 (68.75) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (17.73) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (6.25%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 15 (93.75%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||