Page last updated: 2024-09-23

erionite

Description

erionite: erionite was SY to zeolite (NM); use zeolites (NM) to search through 1993; RN given is for cpd with unknown MF [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID61565
MeSH IDM0221374

Synonyms (5)

Synonym
erionite
12510-42-8
erionite ((k0-1na0-1ca0-0.5)10(al10si26o72).30h2o)
hsdb 7765
Q26841277

Research Excerpts

Overview

ExcerptReference
"Erionite is a non-asbestos fibrous zeolite classified by the International Agency for Research on Cancer (IARC) as a Group 1 carcinogen and is considered today similar to or even more carcinogenic than the six regulated asbestos minerals. "( Ballirano, P; Di Giuseppe, D; Fornasini, L; Giacobbe, C; Giannini, C; Gualtieri, AF; Malferrari, D; Mattioli, M; Moliterni, A; Mugnaioli, E; Raneri, S; Wright, JP, 2023)
"Erionite is a zeolite representing a well-known health hazard. "( Ballirano, P; Boscardin, M; Cenni, M; Giordani, M; Mattioli, M; Pacella, A; Valentini, L, 2017)
"Erionite is a naturally occurring fibrous mineral found in many parts of the world, including the western United States. "( Beaucham, C; Dozier, A; Feldmann, K; Harper, M; King, B, 2018)
"Erionite is a fibrous zeolite, morphologically similar to asbestos and it is assumed to be even more carcinogenic."( Barbone, D; Bertino, P; Bruni, BM; Dogan, AU; Gaudino, G; Germano, S; Marconi, A; Mutti, L; Palumbo, L; Porta, C; Tassi, GF, 2007)
"Erionite is a human and animal carcinogen and one of the most toxic minerals known. "( Dogan, AU; Dogan, M; Hoskins, JA, 2008)
"Erionite is a zeolite mineral of volcanic origin which contains no asbestos. "( Gräsel, B; Kaya, A; Kuntz, C; Rauber, K; Stahl, U, 2008)

Effects

ExcerptReference
"Erionite has a higher degree of carcinogenicity with possible genetic transmission of erionite susceptibility in an autosomal dominant fashion."( Demirer, E; Elamin, EM; Ghattas, CF; Radwan, MO, 2015)
"Erionite has a higher potency in the lung than asbestos and familial clustering of malignant mesothelioma suggests a genetic predisposition to this cancer among affected individuals."( Demir, AU; Emri, S, 2004)
"Erionite has similar chemical and physical properties to amphibole asbestos, which induces autoantibodies in mice. "( Davis, C; Ng, KW; Peña, C; Pfau, JC; Zebedeo, CN, 2014)
"Erionite has been the culprit of numerous malignant mesothelioma cases in Europe and even in North America."( Demirer, E; Elamin, EM; Ghattas, CF; Radwan, MO, 2015)
"Erionite has emerged as the most important example of nonasbestos-mediated cause of mesothelioma in regions such as Turkey where exposure to this type of fiber is highly prevalent. "( Gibbs, A; Jasani, B, 2012)
"Erionite has a higher potency in the lung than asbestos and familial clustering of malignant mesothelioma suggests a genetic predisposition to this cancer among affected individuals."( Demir, AU; Emri, S, 2004)
"Erionite deposits have been reported in many countries; however, it is only in the area of three villages of Cappadocia, Turkey, that environmental exposure to erionite has been demonstrated to be the cause of an epidemic of the disease mesothelioma."( Dogan, AU; Dogan, M; Hoskins, JA, 2008)

Research

Studies (82)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's14 (17.07)18.2507
2000's30 (36.59)29.6817
2010's34 (41.46)24.3611
2020's4 (4.88)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews12 (13.95%)6.00%
Case Studies1 (1.16%)4.05%
Observational0 (0.00%)0.25%
Other73 (84.88%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research Highlights

Safety/Toxicity (4)

ArticleYear
Acute cytotoxicity of mineral fibres observed by time-lapse video microscopy.
Toxicology, 01-30, Volume: 466
2022
New insights into the toxicity of mineral fibres: A combined in situ synchrotron μ-XRD and HR-TEM study of chrysotile, crocidolite, and erionite fibres found in the tissues of Sprague-Dawley rats.
Toxicology letters, May-15, Volume: 274
2017
Biological effects of naturally occurring and man-made fibres: in vitro cytotoxicity and mutagenesis in mammalian cells.
British journal of cancer, Volume: 79, Issue: 9-10
1999
Cytotoxicity of aluminum silicates in primary neuronal cultures.
Neuroscience, Volume: 57, Issue: 2
1993
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (3)

ArticleYear
Assessment of asbestos body formation by high resolution FEG-SEM after exposure of Sprague-Dawley rats to chrysotile, crocidolite, or erionite.
Journal of hazardous materials, Apr-05, Volume: 306
2016
The effect of iron on the biological activities of erionite and mordenite.
Environment international, Volume: 29, Issue: 4
2003
Malignant mesothelioma due to environmental exposure to erionite: follow-up of a Turkish emigrant cohort.
The European respiratory journal, Volume: 13, Issue: 3
1999
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]