Coumarin 314 is a fluorescent dye that has been widely used in various applications, including bioimaging, chemical sensing, and material science. It is a derivative of coumarin, a naturally occurring organic compound found in plants. The dye exhibits strong fluorescence in the blue-green region of the visible spectrum and has been shown to be highly sensitive to changes in its environment. This sensitivity has led to its use in various applications, such as detecting changes in pH, temperature, and the presence of specific molecules. Coumarin 314 is also used as a probe in biological studies to track the movement of molecules and to visualize cellular processes. The dye's relatively high photostability and its ability to be easily modified make it a valuable tool for researchers in a wide range of fields.'
coumarin 314: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 72653 |
| CHEMBL ID | 2000369 |
| CHEBI ID | 51940 |
| SCHEMBL ID | 194640 |
| MeSH ID | M0511150 |
| Synonym |
|---|
| NCI60_002992 |
| nsc338967 |
| 1h,11h-[1]benzopyrano[6,7,8-ij]quinolizine-10-carboxylic acid, 2,3,6,7-tetrahydro-11-oxo-, ethyl ester |
| nsc-338967 |
| coumarin 314 |
| 55804-66-5 |
| ethyl 11-oxo-2,3,6,7-tetrahydro-1h,5h,11h-pyrano[2,3-f]pyrido[3,2,1-ij]quinoline-10-carboxylate |
| OPREA1_687293 |
| coumarin 314, dye content 97 % |
| coumarin 504 |
| ethyl 2,3,6,7-tetrahydro-11-oxo-1h,5h,11h-(1)benzopyrano(6,7,8-ij)quinolizine-10-carboxylate |
| ccris 4963 |
| einecs 259-825-1 |
| nsc 338967 |
| 1h,5h,11h-(1)benzopyrano(6,7,8-ij)quinolizine-10-carboxylic acid, 2,3,6,7-tetrahydro-11-oxo-, ethyl ester |
| CHEBI:51940 , |
| STK409685 |
| C2268 |
| ethyl 2,3,6,7-tetrahydro-11-oxo-1h,5h,11h-[1]benzopyrano[6,7,8-ij]quinolizine-10-carboxylate |
| AKOS000813874 |
| wm5mo60ruo , |
| unii-wm5mo60ruo |
| FT-0624077 |
| F9995-0517 |
| 1h,5h,11h-[1]benzopyrano[6,7,8-ij]quinolizine-10-carboxylic acid, 2,3,6,7-tetrahydro-11-oxo-, ethyl ester |
| BBL028024 |
| SCHEMBL194640 |
| DTXSID4069052 |
| CHEMBL2000369 |
| mfcd00051334 |
| VU0549387-1 |
| ethyl 6,7,9,10-tetrahydro-8h,11h-quinolizino[9,9a, 1-gh]coumarin-3-carboxylate |
| 5-(4-nitrophenyl)isoxazole-3-carboxylicacid |
| VMJKUPWQKZFFCX-UHFFFAOYSA-N |
| ethyl 11-oxo-2,3,5,6,7,11-hexahydro-1h-pyrano[2,3-f]pyrido[3,2,1-ij]quinoline-10-carboxylate |
| coumarin-314 |
| ethyl 4-oxo-3-oxa-13-azatetracyclo[7.7.1.0(2),?.0(1)(3),(1)?]heptadeca-1,5,7,9(17)-tetraene-5-carboxylate |
| VS-08649 |
| Q27123014 |
| c-314 |
| ccris-4963 |
| ethyl 1,2,4,5-tetrahydro-3h,6h,10h-1-benzopyrano[9,9a,1-gh]quinolizin- 10-one-9-oate |
| ethyl 4-oxo-3-oxa-13-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1,5,7,9(17)-tetraene-5-carboxylate |
| T71057 |
| A913750 |
| ethyl11-oxo-2,3,5,6,7,11-hexahydro-1h-pyrano[2,3-f]pyrido[3,2,1-ij]quinoline-10-carboxylate |
| coumarin314 |
| EN300-240267 |
| ethyl 4-oxo-3-oxa-13-azatetracyclo[7.7.1.0^{2,7}.0^{13,17}]heptadeca-1(17),2(7),5,8-tetraene-5-carboxylate |
| ethyl 11-oxo-2,3,5,6,7,11-hexahydro-1h-pyrano[2,3-f] |
| pyrido[3,2,1-ij]quinoline-10-carboxylate |
| Role | Description |
|---|---|
| fluorochrome | A fluorescent dye used to stain biological specimens. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Class | Description |
|---|---|
| 7-aminocoumarins | Any member of the class of coumarins that contains a 7-amino-2H-chromen-2-one skeleton. |
| ethyl ester | Any carboxylic ester resulting from the formal condensation of the carboxy group of a carboxylic acid with ethanol. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (22.13) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||