beta-dolabrin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

beta-dolabrin: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	188981
CHEMBL ID	2270059
CHEBI ID	187575
SCHEMBL ID	13618770
SCHEMBL ID	465267
MeSH ID	M0366358

Synonyms (12)

Synonym
beta-dolabrin
LMPR0102110001
CHEBI:187575
2-hydroxy-6-prop-1-en-2-ylcyclohepta-2,4,6-trien-1-one
4570-11-0
AKOS006275857
2-hydroxy-4-prop-1-en-2-ylcyclohepta-2,4,6-trien-1-one
CHEMBL2270059
SCHEMBL13618770
SCHEMBL465267
DTXSID70196601
4-isopro-penyltropolone

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

Class	Description
cyclic ketone
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (26)

Assay ID	Title	Year	Journal	Article
AID1101101	Antifungal activity against Pycnoporus coccineus IFO-4924 assessed as growth inhibition after 7 days by agar dilution method	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101105	Antifungal activity against Daedalea dickinsii IFO-4979 assessed as growth inhibition after 7 days by agar dilution method	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101094	Insecticidal activity against Tyrophagus putrescentiae assessed as mortality at 0.01 g/m2 after 24 hr by clip method relative to control	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101102	Antifungal activity against Lenzites betulinus IFO-4964 assessed as growth inhibition after 7 days by agar dilution method	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101092	Insecticidal activity against Coptotermes formosanus assessed as mortality at 1 g/m2 after 24 hr relative to control	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101077	Insecticidal activity against Coptotermes formosanus assessed as mortality at 0.02 g/m2 after 48 hr relative to control	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101100	Insecticidal activity against Tyrophagus putrescentiae assessed as mortality at 1 g/m2 after 24 hr by clip method relative to control	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101090	Insecticidal activity against Coptotermes formosanus assessed as mortality at 0.1 g/m2 after 24 hr relative to control	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101075	Insecticidal activity against Coptotermes formosanus assessed as mortality at 0.01 g/m2 after 48 hr relative to control	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101093	Insecticidal activity against Tyrophagus putrescentiae assessed as mortality after 24 hr by clip method	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101091	Insecticidal activity against Coptotermes formosanus assessed as mortality at 0.2 g/m2 after 24 hr relative to control	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101099	Insecticidal activity against Tyrophagus putrescentiae assessed as mortality at 0.5 g/m2 after 24 hr by clip method relative to control	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101088	Insecticidal activity against Coptotermes formosanus assessed as mortality at 0.05 g/m2 after 24 hr relative to control	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101096	Insecticidal activity against Tyrophagus putrescentiae assessed as mortality at 0.05 g/m2 after 24 hr by clip method relative to control	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101103	Antifungal activity against Schizophyllum commune IFO-4928 assessed as growth inhibition after 7 days by agar dilution method	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101071	Insecticidal activity against Coptotermes formosanus assessed as mortality after 24 to 48 hr	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101078	Insecticidal activity against Coptotermes formosanus assessed as mortality at 0.05 g/m2 after 48 hr relative to control	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101089	Insecticidal activity against Coptotermes formosanus assessed as mortality at 0.02 g/m2 after 24 hr relative to control	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101080	Insecticidal activity against Coptotermes formosanus assessed as mortality at 0.2 g/m2 after 48 hr relative to control	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101104	Antifungal activity against Trametes versicolor IFO-4940 assessed as growth inhibition after 7 days by agar dilution method	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101079	Insecticidal activity against Coptotermes formosanus assessed as mortality at 0.1 g/m2 after 48 hr relative to control	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101081	Insecticidal activity against Coptotermes formosanus assessed as mortality at 1 g/m2 after 48 hr relative to control	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101095	Insecticidal activity against Tyrophagus putrescentiae assessed as mortality at 0.02 g/m2 after 24 hr by clip method relative to control	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101087	Insecticidal activity against Coptotermes formosanus assessed as mortality at 0.01 g/m2 after 24 hr relative to control	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101097	Insecticidal activity against Tyrophagus putrescentiae assessed as mortality at 0.1 g/m2 after 24 hr by clip method relative to control	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
AID1101098	Insecticidal activity against Tyrophagus putrescentiae assessed as mortality at 0.2 g/m2 after 24 hr by clip method relative to control	2000	Biological & pharmaceutical bulletin, Aug, Volume: 23, Issue:8	Antifungal activity of Hinokitiol-related compounds on wood-rotting fungi and their insecticidal activities.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	1 (20.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (80.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.74

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.74 (24.57)
Research Supply Index	1.79 (2.92)
Research Growth Index	4.54 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.74)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
chlorpyrifos Chlorpyrifos: An organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.. chlorpyrifos : An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.	2	1	chloropyridine; organic thiophosphate	acaricide; agrochemical; EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; environmental contaminant; insecticide; xenobiotic
beta-thujaplicin beta-thujaplicin: structure. beta-thujaplicin : A monoterpenoid that is cyclohepta-2,4,6-trien-1-one substituted by a hydroxy group at position 2 and an isopropyl group at position 4. Isolated from Thuja plicata and Chamaecyparis obtusa, it exhibits antimicrobial activities.	8.08	5	cyclic ketone; enol; monoterpenoid	antibacterial agent; antifungal agent; antineoplastic agent; antiplasmodial drug; plant metabolite
deet N,N-diethyl-m-toluamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of m-toluic acid with the nitrogen of diethylamine. First developed by the U.S. Army in 1946 for use by military personnel in insect-infested areas, it is the most widely used insect repellent worldwide.	2	1	benzamides; monocarboxylic acid amide	environmental contaminant; insect repellent; xenobiotic
tropolone Tropolone: A seven-membered aromatic ring compound. It is structurally related to a number of naturally occurring antifungal compounds (ANTIFUNGAL AGENTS).. tropolone : A cyclic ketone that is cyclohepta-2,4,6-trien-1-one substituted by a hydroxy group at position 2. It is a toxin produced by the agricultural pathogen Burkholderia plantarii.	7.89	4	alpha-hydroxy ketone; cyclic ketone; enol	bacterial metabolite; fungicide; toxin
gamma-thujaplicin 2-hydroxy-5-isopropyl- 2,4,6-cycloheptatrienone: a metal chelating agent	2.92	4	cyclic ketone
amphotericin b Amphotericin B: Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela.. amphotericin B : A macrolide antibiotic used to treat potentially life-threatening fungal infections.	2	1	antibiotic antifungal drug; macrolide antibiotic; polyene antibiotic	antiamoebic agent; antiprotozoal drug; bacterial metabolite

Condition	Relationship Strength	Studies
Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	2	1
Carcinoma, Ehrlich Tumor A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms.	2	1
Cancer of Stomach [description not available]	2	1
Stomach Neoplasms Tumors or cancer of the STOMACH.	2	1

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