Compounds > avicequinone c
Page last updated: 2024-11-12

avicequinone c

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

avicequinone C: isolated from Avicennia marina; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
AvicenniagenusA plant genus of the family Acanthaceae. Members contain NAPHTHOQUINONES. Black mangroves (common name for the genus) are distinguished from other mangroves by their spike-like aerial roots called pneumatophores that project from the soil or water surrounding the plants.[MeSH]AcanthaceaeA plant family of the order Lamiales. It is characterized by simple leaves in opposite pairs, cystoliths (enlarged cells containing crystals of calcium carbonate), and bilaterally symmetrical and bisexual flowers that are usually crowded together. The common name for Ruellia of wild petunia is easily confused with PETUNIA.[MeSH]

Cross-References

ID SourceID
PubMed CID10563004
CHEMBL ID226175
MeSH IDM000605725

Synonyms (5)

Synonym
avicequinone c
CHEMBL226175
256341-14-7
2-(2-hydroxypropan-2-yl)naphtho[2,3-b]furan-4,9-dione
2-(2-hydroxypropan-2-yl)benzo[f][1]benzofuran-4,9-dione
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (10)

Assay IDTitleYearJournalArticle
AID288741Antimicrobial activity against Mycobacterium aurum SB 66 by micro-broth dilution method2007Journal of natural products, Jun, Volume: 70, Issue:6
Unusual naphthoquinone derivatives from the twigs of Avicennia marina.
AID288739Antimicrobial activity against Candida albicans BMSY 212 by micro-broth dilution method2007Journal of natural products, Jun, Volume: 70, Issue:6
Unusual naphthoquinone derivatives from the twigs of Avicennia marina.
AID288737Antiproliferative activity against human K562 cells2007Journal of natural products, Jun, Volume: 70, Issue:6
Unusual naphthoquinone derivatives from the twigs of Avicennia marina.
AID288742Antimicrobial activity against Mycobacterium vaccae IMET 10670 by microbroth dilution method2007Journal of natural products, Jun, Volume: 70, Issue:6
Unusual naphthoquinone derivatives from the twigs of Avicennia marina.
AID288744Antimicrobial activity against methicillin-resistant Staphylococcus aureus 134/93 by micro-broth dilution method2007Journal of natural products, Jun, Volume: 70, Issue:6
Unusual naphthoquinone derivatives from the twigs of Avicennia marina.
AID288743Antimicrobial activity against Mycobacterium fortuitum B by micro-broth dilution method2007Journal of natural products, Jun, Volume: 70, Issue:6
Unusual naphthoquinone derivatives from the twigs of Avicennia marina.
AID288736Antiproliferative activity against mouse L929 cells2007Journal of natural products, Jun, Volume: 70, Issue:6
Unusual naphthoquinone derivatives from the twigs of Avicennia marina.
AID288745Antimicrobial activity against vancomycin-resistant Enterococcus faecalis 1528 by micro-broth dilution method2007Journal of natural products, Jun, Volume: 70, Issue:6
Unusual naphthoquinone derivatives from the twigs of Avicennia marina.
AID288740Antimicrobial activity against Mycobacterium smegmatis SG 987 by microbroth dilution method2007Journal of natural products, Jun, Volume: 70, Issue:6
Unusual naphthoquinone derivatives from the twigs of Avicennia marina.
AID288738Cytotoxicity against human HeLa cells2007Journal of natural products, Jun, Volume: 70, Issue:6
Unusual naphthoquinone derivatives from the twigs of Avicennia marina.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (4)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 20.83

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index20.83 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.86 (4.65)
Search Engine Demand Index23.28 (26.88)
Search Engine Supply Index3.00 (0.95)

This Compound (20.83)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
ciprofloxacin
Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.. ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.		2.0310aminoquinoline;
cyclopropanes;
fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone;
zwitterion		antibacterial drug;
antiinfective agent;
antimicrobial agent;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
environmental contaminant;
topoisomerase IV inhibitor;
xenobiotic
dihydrotestosterone
Dihydrotestosterone: A potent androgenic metabolite of TESTOSTERONE. It is produced by the action of the enzyme 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE.. 17beta-hydroxyandrostan-3-one : A 17beta-hydroxy steroid that is testosterone in which the 4-5 double bond has been reduced to a single bond with unspecified configuration at position 5.. 17beta-hydroxy-5alpha-androstan-3-one : A 17beta-hydroxy steroid that is testosterone in which the 4,5 double bond has been reduced to a single bond with alpha-configuration at position 5.		2.592017beta-hydroxy steroid;
17beta-hydroxyandrostan-3-one;
3-oxo-5alpha-steroid		androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite
paclitaxel
Taxus: Genus of coniferous yew trees or shrubs, several species of which have medicinal uses. Notable is the Pacific yew, Taxus brevifolia, which is used to make the anti-neoplastic drug taxol (PACLITAXEL).		2.0310taxane diterpenoid;
tetracyclic diterpenoid		antineoplastic agent;
human metabolite;
metabolite;
microtubule-stabilising agent
amphotericin b
Amphotericin B: Macrolide antifungal antibiotic produced by Streptomyces nodosus obtained from soil of the Orinoco river region of Venezuela.. amphotericin B : A macrolide antibiotic used to treat potentially life-threatening fungal infections.		2.0310antibiotic antifungal drug;
macrolide antibiotic;
polyene antibiotic		antiamoebic agent;
antiprotozoal drug;
bacterial metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Alopecia Cicatrisata
[description not available]		02.5920
Alopecia
Absence of hair from areas where it is normally present.		02.5920