Page last updated: 2024-11-12

altemicidin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

altemicidin: sulfamino given in first source; monoterpene alkaloid; isolated from Actinomycete [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID11036174
CHEMBL ID3586273
SCHEMBL ID1229355
MeSH IDM0171445

Synonyms (19)

Synonym
1h-2-pyrindine-7-carboxylic acid, 2,4a,5,6,7,7a-hexahydro-4-(aminocarbonyl)-7-(((aminosulfonyl)acetyl)amino)-6-hydroxy-2-methyl-, (4ar-(4a-alpha,6-beta,7-beta,7a-alpha))-
artemicidin
brn 4769528
artemicidine
altemicidin
125399-82-8
(-)-artemicidine
(-)-altemicidin
39e2x82jvd ,
unii-39e2x82jvd
SCHEMBL1229355
CHEMBL3586273
DTXSID20925120
(4ar,6s,7r,7as)-4-carbamoyl-6-hydroxy-2-methyl-7-[(2-sulfamoylacetyl)amino]-4a,5,6,7a-tetrahydro-1h-cyclopenta[c]pyridine-7-carboxylic acid
(4ar,6s,7r,7as)-4-(aminocarbonyl)-7-((2-(aminosulfonyl)acetyl)amino)-2,4a,5,6,7,7a-hexahydro-6-hydroxy-2-methyl-1h-cyclopenta(c)pyridine-7-carboxylic acid
1h-2-pyrindine-7-carboxylic acid, 4-(aminocarbonyl)-7-(((aminosulfonyl)acetyl)amino)-2,4a,5,6,7,7a-hexahydro-6-hydroxy-2-methyl-, (4ar-(4a.alpha.,6.beta.,7.beta.,7a.alpha.))-
1h-cyclopenta(c)pyridine-7-carboxylic acid, 4-(aminocarbonyl)-7-((2-(aminosulfonyl)acetyl)amino)-2,4a,5,6,7,7a-hexahydro-6-hydroxy-2-methyl-, (4ar,6s,7r,7as)-
1h-cyclopenta(c)pyridine-7-carboxylic acid, 4-(aminocarbonyl)-7-(((aminosulfonyl)acetyl)amino)-2,4a,5,6,7,7a-hexahydro-6-hydroxy-2-methyl-, (4ar-(4a.alpha.,6.beta.,7.beta.,7a.alpha.))-
AKOS040756398

Research Excerpts

Overview

Altemicidin is a monoterpene alkaloid.

ExcerptReferenceRelevance
"Altemicidin is a monoterpene alkaloid."( Altemicidin, a new acaricidal and antitumor substance. II. Structure determination.
Ikeda, D; Kurasawa, S; Naganawa, H; Nakamura, H; Okami, Y; Takahashi, A; Takeuchi, T, 1989
)
2.44
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (7)

Assay IDTitleYearJournalArticle
AID1230318Cytotoxicity against mouse L1210 cells assessed as growth inhibition after 48 hrs by coulter counter analysis2015Journal of natural products, Jun-26, Volume: 78, Issue:6
Natural Product Primary Sulfonamides and Primary Sulfamates.
AID1230316Toxicity in brine shrimp after 48 hrs2015Journal of natural products, Jun-26, Volume: 78, Issue:6
Natural Product Primary Sulfonamides and Primary Sulfamates.
AID1230317Acaricidal activity against Tetranychus urticae infected on kidney bean leaves assessed as prevention of infection at 10 ppm after 14 days by green house pot test relative to control2015Journal of natural products, Jun-26, Volume: 78, Issue:6
Natural Product Primary Sulfonamides and Primary Sulfamates.
AID1230320Acute toxicity in iv dose mouse2015Journal of natural products, Jun-26, Volume: 78, Issue:6
Natural Product Primary Sulfonamides and Primary Sulfamates.
AID1849863Antiproliferative activity against human IMC cells assessed as inhibition of cell proliferation incubated for 48 hrs by Coulter counter method2021European journal of medicinal chemistry, Jan-15, Volume: 210Chemistry, biosynthesis and biological activity of terpenoids and meroterpenoids in bacteria and fungi isolated from different marine habitats.
AID1230319Cytotoxicity against mouse invasive mammary carcinoma cells assessed as growth inhibition after 48 hrs by coulter counter analysis2015Journal of natural products, Jun-26, Volume: 78, Issue:6
Natural Product Primary Sulfonamides and Primary Sulfamates.
AID1849862Antiproliferative activity against mouse L1210 cells assessed as inhibition of cell proliferation incubated for 48 hrs by Coulter counter method2021European journal of medicinal chemistry, Jan-15, Volume: 210Chemistry, biosynthesis and biological activity of terpenoids and meroterpenoids in bacteria and fungi isolated from different marine habitats.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (20.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's3 (30.00)24.3611
2020's2 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 23.20

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index23.20 (24.57)
Research Supply Index2.40 (2.92)
Research Growth Index5.01 (4.65)
Search Engine Demand Index21.17 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (23.20)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (20.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (80.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]