Page last updated: 2024-12-08

abt 491

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

ABT 491: a highly potent platelet-activating factor receptor antagonist; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID154086
SCHEMBL ID7943577
MeSH IDM0278815

Synonyms (25)

Synonym
abt-491 hydrochloride, >=98% (hplc)
abt-491
1h-indole-1-carboxamide, 4-ethynyl-3-(3-fluoro-4-((2-methyl-1h-imidazo(4,5-c)pyridin-1-yl)methyl)benzoyl)-n,n-dimethyl-, monohydrochloride
4-ethynyl-3-(3-fluoro-4-((2-methyl-1h-imidazo(4,5-c)pyridin-1-yl)methyl)benzoyl)-n,n-dimethyl-1h-indole-1-carboxamide monohydrochloride
abt 491 hydrochloride
unii-n7ig7z867j
4-ethynyl-n,n-dimethyl-3-(3-fluoro-4-((2-methyl-1h-imidazo-(4,5-c)pyridin-1-yl)methyl)benzoyl)-1h-indole-1-carboxamide hydrochloride
n7ig7z867j ,
abt 491
4-ethynyl-n,n-dimethyl-3-[3-fluoro-4-[(2-methyl-1h-imidazo-[4,5-c]pyridin-1-yl)methyl]benzoyl]-1h-indole-1-carboxamide hydrochloride
189689-94-9
abt-491 hydrochloride
a-137491
AKOS015889278
methyl-1h-imidazo(4,5-c)pyridin-1-yl)methyl)benzoyl)-n,n-dimethyl-, hydrochloride
(4-ethynyl-n,n-dimethyl-3-(3-fluoro-4-((2-methyl-1h-imidazo-(4,5-c)pyridin-1-yl)methyl)benzoyl)-1h-indole-1-carboxamide hydrochloride
SCHEMBL7943577
DTXSID90172381
J-012241
4-ethynyl-3-(3-fluoro-4-((2-methyl-1h-imidazo[4,5-c]pyridin-1-yl)methyl)benzoyl)-n,n-dimethyl-1h-indole-1-carboxamide hydrochloride
paf receptor antagonist, abt-491 - cas 189689-94-9
a 137491
4-ethynyl-3-[3-fluoro-4-[(2-methyl-3h-imidazo[4,5-c]pyridin-1-ium-1-yl)methyl]benzoyl]-n,n-dimethylindole-1-carboxamide;chloride
4-ethynyl-3-[3-fluoro-4-[(2-methylimidazo[4,5-c]pyridin-1-yl)methyl]benzoyl]-n,n-dimethylindole-1-carboxamide;hydrochloride
1h-indole-1-carboxamide, 4-ethynyl-3-[3-fluoro-4-[(2-methyl-1h-imidazo[4,5-c]pyridin-1-yl)methyl]benzoyl]-n,n-dimethyl-, hydrochloride (1:1)
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (33.33)18.2507
2000's1 (11.11)29.6817
2010's3 (33.33)24.3611
2020's2 (22.22)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 21.20

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index21.20 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index5.15 (4.65)
Search Engine Demand Index20.59 (26.88)
Search Engine Supply Index3.50 (0.95)

This Compound (21.20)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]