Page last updated: 2024-12-06

1-indanol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

1-Indanol is a bicyclic organic compound with a fused benzene ring and cyclopentane ring. It is a colorless solid with a melting point of 45-47°C and a boiling point of 243°C. 1-Indanol has been studied for its potential therapeutic applications, particularly in the treatment of anxiety, depression, and epilepsy. Its effects are believed to be related to its interaction with the serotonin system in the brain. Studies have shown that 1-indanol has anxiolytic and antidepressant properties in animal models. Furthermore, it has been shown to inhibit the activity of certain enzymes, such as cyclooxygenase (COX), which are involved in inflammation. The synthesis of 1-indanol typically involves the reduction of indanone, a cyclic ketone. Its importance lies in its potential as a lead compound for the development of new therapeutic agents for various neurological and inflammatory disorders. '

Cross-References

ID SourceID
PubMed CID22819
CHEMBL ID4564909
CHEBI ID16697
SCHEMBL ID57132
SCHEMBL ID1747186
MeSH IDM0066556

Synonyms (53)

Synonym
1-hydroxyhydrindene
CHEBI:16697
2,3-dihydro-1h-inden-1-ol
1h-inden-1-ol, 2,3-dihydro-
1h-indenol, 2,3-dihydro-
indanol
6351-10-6
nsc31258
1-indanol ,
nsc-31258
1h-inden-1-ol,3-dihydro-
einecs 253-146-4
brn 2042960
inchi=1/c9h10o/c10-9-6-5-7-3-1-2-4-8(7)9/h1-4,9-10h,5-6h
indan-1-ol
C01710
1-indanol, 98%
1-hydroxyindan
H0516
AKOS000121032
AM804173
unii-lhg5bd7lor
nsc 31258
lhg5bd7lor ,
einecs 228-755-3
ai3-05996
4-06-00-03824 (beilstein handbook reference)
36643-74-0
FT-0604448
FT-0638529
FT-0632834
SCHEMBL57132
AKOS016050359
SCHEMBL1747186
(-)-indanol
1-indanole
DS-3145
mfcd00003797
CS-0017842
SY014889
rasagiline metabolite, indanol
(+/-)-1-indanol
Q27102031
1-hydroxyindane
indan-1-ol (1-indanol)
SY275070
A914723
I10213
CHEMBL4564909
DTXSID10871162
EN300-21659
SY289024
(+/-)-1-hydroxyindan
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
xenobioticA xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (3)

ClassDescription
indanes
aromatic alcoholAny alcohol in which the alcoholic hydroxy group is attached to a carbon which is itself bonded to an aromatic ring.
secondary alcoholA secondary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has two other carbon atoms attached to it.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (7.69)18.7374
1990's4 (30.77)18.2507
2000's4 (30.77)29.6817
2010's2 (15.38)24.3611
2020's2 (15.38)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 31.19

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index31.19 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index5.21 (4.65)
Search Engine Demand Index33.49 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (31.19)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]