Page last updated: 2024-12-06
1,3-dithiolane
1,3-Dithiolane is a heterocyclic organic compound with the formula C3H6S2. It is a colorless liquid with a characteristic odor. 1,3-Dithiolane is a versatile building block in organic synthesis, particularly in the preparation of sulfur-containing compounds. It is also used as a reagent in the synthesis of polymers and pharmaceuticals. The compound is known to be a useful precursor to various sulfur-containing compounds, and its synthesis is often carried out by the reaction of 1,2-dibromoethane with sodium sulfide. 1,3-Dithiolane can act as a protecting group for carbonyl compounds, forming a stable cyclic thioacetal. This property is valuable in organic synthesis, as it allows for the selective modification of carbonyl groups while leaving other functional groups untouched.'
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 20970 |
| CHEBI ID | 38079 |
| SCHEMBL ID | 28510 |
| MeSH ID | M0060327 |
Synonyms (17)
| Synonym |
|---|
| nsc193357 |
| 1,3-dithiolane |
| 4829-04-3 |
| nsc-193357 |
| 1,3-dithiacyclopentane |
| CHEBI:38079 |
| dithiolane |
| nsc 193357 |
| inchi=1/c3h6s2/c1-2-5-3-4-1/h1-3h |
| 1,3-dithiolane, 97% |
| unii-341g58g6yl |
| 341g58g6yl , |
| AKOS025293915 |
| SCHEMBL28510 |
| mfcd00041425 |
| DTXSID90197473 |
| Q27117371 |
Drug Classes (1)
| Class | Description |
|---|
| dithiolane | |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Research
Studies (9)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 39.08
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 39.08 (24.57) | | Research Supply Index | 2.40 (2.92) | | Research Growth Index | 4.73 (4.65) | | Search Engine Demand Index | 53.49 (26.88) | | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 10 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |